Novel Expression of Neuropeptide Y (NPY) mRNA in Hypothalamic Regions during Development: Region-Specific Effects of Maternal Deprivation on NPY and Agouti-Related Protein mRNA [PDF]
, 2001 Kelly Grove +2 more
openalex +1 more source
Estrogen synthesized in the central nervous system enhances MC4R expression and reduces food intake
The FEBS Journal, Volume 292, Issue 15, Page 3900-3909, August 2025.Estrogen is regulated by the rate‐limiting enzyme aromatase. This study examines how neuroestrogens, estrogen produced in the brain, regulate appetite through the hypothalamus. Using ovariectomized, aromatase knockout, and brain‐specific aromatase‐restored mice, the study found that neuroestrogens suppress appetite by influencing genes like Mc4r.
Takanori Hayashi +8 more
wiley +1 more source
GH-Releasing Peptide-2 Increases Fat Mass in Mice Lacking NPY: Indication for a Crucial Mediating Role of Hypothalamic Agouti-Related Protein [PDF]
, 2002 Matthias H. Tschöp +3 more
openalex +2 more sources
Genetic Biomarkers for Periodontal Diseases: A Systematic Review
Journal of Clinical Periodontology, Volume 52, Issue S29, Page 182-210, August 2025.ABSTRACT Aims To identify genetic biomarkers that may be used in the diagnosis, prevention or management of different forms of periodontal disease. Materials and Methods Following protocol registration and PICOTS (patient, intervention, comparison, outcome, time, studies) questions, a systematic search of the literature was conducted (PudMed, Ovid ...
H. Dommisch +6 more
wiley +1 more source
Mechanisms of enteric neuropathy in diverse contexts of gastrointestinal dysfunction
Neurogastroenterology &Motility, Volume 37, Issue 8, August 2025.Abstract The enteric nervous system (ENS) commands moment‐to‐moment gut functions through integrative neurocircuitry housed in the gut wall. The functional continuity of ENS networks is disrupted in enteric neuropathies and contributes to major disturbances in normal gut activities including abnormal gut motility, secretions, pain, immune dysregulation,
Julia R. Jamka, Brian D. Gulbransen
wiley +1 more source
Leptin Differentially Regulates NPY and POMC Neurons Projecting to the Lateral Hypothalamic Area
Neuron, 1999 C. Elias +8 more
semanticscholar +1 more source
Veterinary Dermatology, Volume 36, Issue 4, Page 401-411, August 2025.Background – Itch is a common symptom in skin disorders. While the neural pathways of itch transmission from the skin to the brain are well‐understood in rodents, the same pathways in dogs remain unclear. The knowledge gap hinders the development of effective treatments for canine itch‐related disorders.
Chie Tamamoto‐Mochizuki +1 more
wiley +1 more source
Cerebrospinal Fluid and Plasma Concentrations of Leptin, NPY, andα -MSH in Obese Women and Their Relationship to Negative Energy Balance [PDF]
, 2001 Su-Youn Nam +5 more
openalex +1 more source