Results 241 to 250 of about 57,297 (272)
Some of the next articles are maybe not open access.
2006
Genetic models such as Y receptor knockout and leptin knockout mice have begun to reveal some of the individual functions of the different Y receptors. The finding that some of these receptors appear to be involved in the regulation of bone formation via a hypothalamic relay, has revealed not only a previously unknown and novel function of the Y ...
Susan J, Allison, Herbert, Herzog
openaire +2 more sources
Genetic models such as Y receptor knockout and leptin knockout mice have begun to reveal some of the individual functions of the different Y receptors. The finding that some of these receptors appear to be involved in the regulation of bone formation via a hypothalamic relay, has revealed not only a previously unknown and novel function of the Y ...
Susan J, Allison, Herbert, Herzog
openaire +2 more sources
Current Topics in Medicinal Chemistry, 2007
Hypertension-induced left ventricular hypertrophy (LVH), along with ischemic heart disease, result in LV remodeling as part of a continuum that often leads to congestive heart failure. The neurohormonal model has been used to underpin many treatment strategies, but optimal outcomes have not been achieved.
McDermott, Barbara, Bell, David
openaire +2 more sources
Hypertension-induced left ventricular hypertrophy (LVH), along with ischemic heart disease, result in LV remodeling as part of a continuum that often leads to congestive heart failure. The neurohormonal model has been used to underpin many treatment strategies, but optimal outcomes have not been achieved.
McDermott, Barbara, Bell, David
openaire +2 more sources
Parasites flicking the NPY gene on the host's switchboard: why NPY?
The FASEB Journal, 1999ABSTRACT It was investigated whether up‐regulation of the NPY gene by the schistosome Trichobilharzia ocellata in its snail host Lymnaea stagnalis redirects the host's energy flows.
de Jong-Brink, M. +3 more
openaire +4 more sources
Interactions between NPY and its receptor: assessment using anti-NPY antibodies
Regulatory Peptides, 1994The present data show that monoclonal antibodies (NPY02, NPY03, NPY04, NPY05) directed against 4 distinct epitopes on NPY may have different actions on NPY binding and NPY-induced cellular responses. NPY02 and NPY05 recognize the 11-24 and 32-36 amidated form of NPY, respectively.
Grouzmann, E. +5 more
openaire +2 more sources
Neuropeptide Y (Npy) and Npy Receptors in The Rat Pineal Gland
2005NPY is considered to play an important role in pineal function, because it is co-stored with the dominant pineal transmitter noradrenaline. However, little evidence from the literature suggests that NPY alone is a strong regulator of melatonin synthesis or secretion and it is therefore more likely that NPY modulates noradrenergic neurotransmission in ...
Mikkelsen, J. D., Hauser, F., Olcese, J.
openaire +2 more sources
Distinction of NPY receptors in vitro and in vivo. II. Differential effects of NPY and NPY-(18-36)
American Journal of Physiology-Heart and Circulatory Physiology, 1990We have studied the hemodynamic effects of neuropeptide Y (NPY) and its COOH-terminal fragment NPY-(18–36) in conscious rats. Intra-arterial injection of NPY rapidly elevated systemic vascular resistance (SVR), which remained high for greater than 30 min. Cardiac output (CO) decreased, and it remained low for greater than 30 min.
Scott, N. A. +7 more
openaire +3 more sources
NPY regulation of bone remodelling
Neuropeptides, 2009Neuropeptide Y (NPY), a classic neuronal regulator of energy homeostasis, is now also known to be involved in the control of bone homeostasis. Of the five known Y receptors through which the NPY family of ligands signals, the Y1 and Y2 receptors have so far been implicated in the control of osteoblast activity and thus bone formation. Analysis of brain
Nicola J, Lee, Herbert, Herzog
openaire +2 more sources
Spinal mechanisms of NPY analgesia
Peptides, 2007We review previously published data, and present some new data, indicating that spinal application of neuropeptide Y (NPY) reduces behavioral and neurophysiological signs of acute and chronic pain. In models of acute pain, early behavioral studies showed that spinal (intrathecal) administration of NPY and Y2 receptor agonists decrease thermal ...
Peter A, Smith +4 more
openaire +2 more sources
Neuropeptide Y (NPY) and NPY Y1 receptor in periodontal health and disease
Archives of Oral Biology, 2009Neuropeptide Y (NPY) coordinates inflammation and bone metabolism which are central to the pathogenesis of periodontitis. The present study was designed to determine whether NPY was quantifiable in human gingival crevicular fluid (GCF) and to test the null hypothesis that GCF levels of NPY were the same in periodontal health and disease.
Lundy, Fionnuala T. +2 more
openaire +3 more sources