α2‐Adrenoceptor and NPY receptor‐mediated contractions of porcine isolated blood vessels: evidence for involvement of the vascular endothelium [PDF]
, 1999 R. E. Roberts, Dave Kendal, V.G. Wilson
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Journal of Neuroendocrinology, EarlyView.Alterations in the expression levels of D2S and D2L resulted in obesity and metabolic syndrome such as abdominal fat accumulation and hyperglycemia in D2L KO mice fed with a high‐fat diet, compared to WT mice. This may be partly due to increased food intake.
Hanna Gonzalez +5 more
wiley +1 more source
Neuropeptide Y (NPY) as a therapeutic target for neurodegenerative diseases
Neurobiology of Disease, 2016 Neuropeptide Y (NPY) and NPY receptors are widely expressed in the mammalian central nervous system. Studies in both humans and rodent models revealed that brain NPY levels are altered in some neurodegenerative disorders, such as Alzheimer's disease ...
Joana Duarte-Neves +2 more
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Morphological Evidence for Direct Interaction between Arcuate Nucleus Neuropeptide Y (NPY) Neurons and Gonadotropin-Releasing Hormone Neurons and the Possible Involvement of NPY Y1 Receptors [PDF]
, 1999 C. Li
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Journal of Neuroendocrinology, EarlyView.Abstract Recent studies have shown a link between disrupted circadian rhythms and the development of chronic opioid‐induced negative effects. Both animal and human studies show a significant bidirectional relationship between the circadian system and opioid effects.
Nasrin Mehranfard +2 more
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Mediators of Inflammation, 2014 Smoking deregulates neuroendocrine responses to pain supporting production of neuropeptide Y (NpY) by direct stimulation of nicotinic receptors or by inhibiting adipokine leptin.
Maria I. Bokarewa +4 more
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Stress alters hypothalamic gene expression in adolescent male Golden hamsters
Journal of Neuroendocrinology, EarlyView.Abstract In Golden hamsters (Mesocricetus auratus), a two‐week exposure to chronic social stress in adolescence causes acceleration of agonistic behavior, enhanced adult aggression, impaired waiting impulsivity, and higher food intake, body fat, and long‐term increased body weight.
Kevin M. Moran +3 more
wiley +1 more source
The pharmacotherapeutic potential of neuropeptide Y for chronic pain
Journal of Internal Medicine, EarlyView.Abstract Chronic pain is a major medical problem that requires new therapeutic options. Discovered by Victor Mutt in 1982, neuropeptide Y (NPY) is rapidly emerging as a master regulator of pain relief. Genetic knockdown of NPY or pharmacological inhibition of its receptors demonstrates that NPY signaling tonically inhibits indices of chronic ...
Al A. Nie, Bradley K. Taylor
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Development of neuropeptide Y-ergic innervation of the small intestine in rats
Учёные записки Казанского университета: Серия Естественные науки, 2018 Neuropeptide Y (NPY) acts as a neurotransmitter in the autonomic nervous system, including in the metasympathetic intramural ganglia of the intestine.
P.M. Masliukov +3 more
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Adrenalectomy reduces neuropeptide Y–induced insulin release and NPY receptor expression in the rat ventromedial hypothalamus [PDF]
, 2000 Todd Wisialowski +6 more
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