NPY controls fear conditioning and fear extinction by combined action on Y1 and Y2 receptors
British Journal of Pharmacology, 2012 BACKGROUND AND PURPOSE Neuropeptide Y (NPY) and its receptors have been implicated in the control of emotional‐affective processing, but the mechanism is unclear.
D. Verma +3 more
semanticscholar +1 more source
Tonic inhibition of accumbal spiny neurons by extrasynaptic 4 GABAA receptors modulates the actions of psychostimulants [PDF]
, 2014 Within the nucleus accumbens (NAc), synaptic GABAA receptors (GABAARs) mediate phasic inhibition of medium spiny neurons (MSNs) and influence behavioral responses to cocaine.
Belelli, D +8 more
core +1 more source
Modeling Obesity and Weight Loss in Mice Using Novel AAV Approaches
Obesity, EarlyView.ABSTRACT Objective This study utilized AAV gene delivery as an approach to induce and reverse hyperphagia in mice. We hypothesized that the delivery of orexigenic neuropeptides to the brain via AAV precipitates obesity and that the implementation of genetic switches to reverse transgene expression would elicit weight loss.
Hunter G. Sellers +12 more
wiley +1 more source
Mouse circadian plasma leptin and active ghrelin rhythms under ad libitum and scheduled feeding [PDF]
, 2007 Thesis (M.S.) University of Alaska Fairbanks, 2007Light is the strongest timing cue for the circadian system, but non-photic cues can also entrain the master circadian clock, i.e., suprachiasmatic nuclei (SCN).
Wan, Haiting
core
A quantitative study of neurochemically-defined populations of inhibitory interneurons in the superficial dorsal horn of the mouse spinal cord [PDF]
, 2017 Around a quarter of neurons in laminae I-II of the dorsal horn are inhibitory interneurons. These play an important role in modulating somatosensory information, including that perceived as pain or itch.
Boyle, Kieran A. +7 more
core +1 more source
Influence of Asymmetry on the Molecular and Electronic Structures of μ‐Oxo Diferric Complexes
Zeitschrift für anorganische und allgemeine Chemie, EarlyView.The 6‐methyl substituents at the pyridines (shown in red) enforce longer MNpy bonds than without them (shown in green).The asymmetric dinucleating susanH2Me2 is used for the synthesis of a μ‐oxo diferric complex. Comparison to the two symmetric complexes of susan and susan6−Me shows a strong effect on the redox potentials.
Sören Jansen +4 more
wiley +1 more source
Scientific Reports, 2019 Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibitory control of neuropathic pain, but its mechanism of action is complicated by the expression of its receptors at multiple sites in the dorsal horn: NPY Y1 receptors (Y1Rs) on post ...
T. Nelson +6 more
semanticscholar +1 more source
Npy deletion in an alcohol non-preferring rat model elicits differential effects on alcohol consumption and body weight. [PDF]
, 2016 Neuropeptide Y (NPY) is widely expressed in the central nervous system and influences many physiological processes. It is located within the rat quantitative trait locus (QTL) for alcohol preference on chromosome 4.
Bell, Richard L. +8 more
core +1 more source
Mycosis Fungoides Is a Proliferation of Multiple Mutational Subclones
The Journal of Dermatology, EarlyView.ABSTRACT Mycosis fungoides (MF) is a unique type of lymphoma with an excellent prognosis presenting with a wide variety of clinical and histological findings. Recent sophisticated research techniques have revealed that very slow changes in the clinical and histological pictures of one patient over time are due to intratumoral heterogeneity.
Ryoma Honda +2 more
wiley +1 more source
Andrology, EarlyView.Abstract Background Penile sexual sensation relies on intricate neural structures that remain incompletely characterized. Immunohistological insights into their development and organization can enhance understanding of penile neuroanatomy and function, while optimizing surgical outcomes.
Alfonso Cepeda‐Emiliani +6 more
wiley +1 more source