KNDy neurons as an indirect target of insulin‐like growth factor‐1
Abstract Neurons in the arcuate nucleus of the hypothalamus (ARH) that coexpress kisspeptin, neurokinin B, and dynorphin (KNDy neurons) are considered the gonadotropin‐releasing hormone (GnRH) pulse generator necessary for fertility. KNDy neurons are also metabolic sensors controlling the hypothalamic–pituitary‐gonadal (HPG) axis.
Josiane do N. Silva +8 more
wiley +1 more source
Modulation by NPY/NPF-like receptor underlies experience-dependent, sexually dimorphic learning [PDF]
Sonu Peedikayil‐Kurien +3 more
openalex +1 more source
ABSTRACT Intraspecific competition due to for example, density, has substantial influence on fitness dynamics and life histories, but the underlying physiological mechanisms are often complex and the molecular basis unclear. Further, designing laboratory experiments to measure physiological responses that reflect natural conditions is challenging. Here,
Morgane Frapin +8 more
wiley +1 more source
Pharmacological inhibition of NPY receptors illustrates dissociable features of experimental colitis in the mouse DSS model: Implications for preclinical evaluation of efficacy in an inflammatory bowel disease model. [PDF]
Ruiz HH +6 more
europepmc +1 more source
Abstract Topical application of l‐menthol, a pharmacological cold‐mimetic and agonist of the cold‐sensing receptor TRPM8 (transient receptor potential cation channel subfamily M member 8), has been shown to stimulate brown adipose tissue (BAT) thermogenesis and reduce weight gain in both obese and lean male mice, without affecting energy intake.
Annalaura Bellucci +8 more
wiley +1 more source
Early Nutritional Programing: Unlocking the Potential of Fish for Sustainable Aquaculture
Nutritional programing, which explores the link between early nutritional conditions and their long‐term effects on animals, is a developing field within fish biology. Suboptimal nutritional status during early life is strongly associated with a higher risk of metabolic consequences later in life, including permanent growth retardation, impaired neural
Shivendra Kumar +5 more
wiley +1 more source
Identification of Novel Benzimidazole Derivatives as NPY Y5 Receptor Antagonists
Yusuke Tamura
openalex +2 more sources
Identification of novel and orally active spiroindoline NPY Y5 receptor antagonists
Toshihiro Sakamoto +16 more
openalex +1 more source
Neuroblastoma cells with overexpressed MYCN retain their capacity to undergo neuronal differentiation [PDF]
Culp, Lloyd A +8 more
core +2 more sources

