Results 21 to 30 of about 2,285,473 (285)

The effect of insulin receptor deletion in neuropeptide Y neurons on hippocampal dependent cognitive function in aging mice [PDF]

Journal of Integrative Neuroscience, 2022
Insulin is known to act in the central nervous system to regulate several physiological and behavioural outcomes, including energy balance, glucose homeostasis and cognitive functioning. However, the neuronal populations through which insulin enhances
Elisabeth K. Goodman, Caitlin S. Mitchell, Jonathan D. Teo, Joanne M. Gladding, Kirsten N. Abbott, Neda Rafiei, Lei Zhang, Herbert Herzog, Denovan P. Begg   +8 more
doaj   +1 more source

Sympathetic nervous system catecholamines and neuropeptide Y neurotransmitters are upregulated in human NAFLD and modulate the fibrogenic function of hepatic stellate cells. [PDF]

PLoS ONE, 2013
Sympathetic nervous system (SNS) signalling regulates murine hepatic fibrogenesis through effects on hepatic stellate cells (HSC), and obesity-related hypertension with SNS activation accelerates progression of non-alcoholic fatty liver disease (NAFLD ...
Barbara Sigala, Chad McKee, Junpei Soeda, Valerio Pazienza, Maelle Morgan, Ching-I Lin, Clare Selden, Sara Vander Borght, Gianluigi Mazzoccoli, Tania Roskams, Manlio Vinciguerra, Jude A Oben   +11 more
doaj   +1 more source

A companion to the preclinical common data elements and case report forms for neuropathology studies in epilepsy research. A report of the TASK3 WG2 Neuropathology Working Group of the ILAE/AES Joint Translational Task Force

Epilepsia Open, EarlyView., 2022
Abstract The International League Against Epilepsy/American Epilepsy Society (ILAE/AES) Joint Translational Task Force initiated the TASK3 working group to create common data elements (CDEs) for various aspects of preclinical epilepsy research studies, which could help improve the standardization of experimental designs.
Eleonora Aronica, Devin K. Binder, Meinrad Drexel, Chrysanthy Ikonomidou, Shilpa D. Kadam, Guenther Sperk, Christian Steinhäuser   +6 more
wiley   +1 more source

Ancient grandeur of the vertebrate neuropeptide Y system shown by the coelacanth Latimeria chalumnae

Frontiers in Neuroscience, 2013
The neuropeptide Y (NPY) family receptors and peptides have previously been characterized in several tetrapods, teleost fishes and in a holocephalan cartilaginous fish.
Dan eLarhammar, Christina A Bergqvist
doaj   +1 more source

Neuropeptide Y directly reduced apoptosis of granulosa cells, and the expression of NPY and its receptors in PCOS subjects

Journal of Ovarian Research, 2023
Background Most women with anovulatory infertility show polycystic ovarian syndrome (PCOS), and androgen excess is known as a key factor involved in pathogenicity of PCOS.
Yoko Urata, Reza Salehi, Brandon A. Wyse, Sahar Jahangiri, Clifford L. Librach, Chii-Ruey Tzeng, Yutaka Osuga, Benjamin Tsang   +7 more
doaj   +1 more source

Activation of NPY receptors suppresses excitatory synaptic transmission in a taste-feeding network in the lower brain stem.

American Journal of Physiology. Regulatory Integrative and Comparative Physiology, 2012
Consummatory responses to taste stimuli are modulated by visceral signals processed in the caudal nucleus of the solitary tract (cNST) and ventrolateral medulla. On the basis of decerebrate preparations, this modulation can occur through local brain stem
Zhixiong Chen, S. Travers, J. Travers
semanticscholar   +1 more source

A Promising Therapeutic Target for Metabolic Diseases: Neuropeptide Y Receptors in Humans

Cellular Physiology and Biochemistry, 2017
Human neuropeptide Y (hNPY) is one of the most widely expressed neurotransmitters in the human central and peripheral nervous systems. It consists of 36 highly conserved amino acid residues, and was first isolated from the porcine hypothalamus in 1982 ...
Min Yi, Hekai Li, Zhiye Wu, Jianyun Yan, Qicai Liu, Caiwen Ou, Minsheng Chen   +6 more
doaj   +1 more source

Interactions of zebrafish peptide YYb with the neuropeptide Y-family receptors Y4, Y7, Y8a and Y8b

Frontiers in Neuroscience, 2013
The neuropeptide Y (NPY) system influences numerous physiological functions including feeding behavior, endocrine regulation, and cardiovascular regulation. In jawed vertebrates it consists of 3-4 peptides and 4-7 receptors.
Görel eSundström, Tomas A Larsson, Bo eXu, Johan eHeldin, Dan eLarhammar   +4 more
doaj   +1 more source

NPY receptor subtype in the rabbit isolated ileum [PDF]

British Journal of Pharmacology, 1999
The purpose of this work was to verify the hypothesis that the rabbit ileum is a selective preparation for the NPY Y5 receptor by using new selective antagonists recently synthesized. Spontaneous contractions of the rabbit isolated ileum were recorded and binding experiments were performed in cells expressing the human NPY Y1, Y2, Y4 or Y5 receptor ...
Jean-Pierre Galizzi, Philippe Beauverger, Jean A. Boutin, Jacques Duhault, Marianne Rodriguez, Michel Félétou, Jean-Paul Nicolas   +6 more
openaire   +3 more sources

Dead end for NPY Y5-receptor antagonists? [PDF]

Nature Reviews Drug Discovery, 2002
Peter Kirkpatrick
openalex   +3 more sources