Results 61 to 70 of about 2,285,473 (285)

Neuropeptide Y receptors: How to get subtype selectivity

Frontiers in Endocrinology, 2013
The neuropeptide Y system is a multireceptor/multiligand system consisting of four receptors in humans (hY1, hY2, hY4, hY5) and three agonists (NPY, PYY, PP) that activate these receptors with different potency.
Xavier ePedragosa Badia, Jan eStichel, Annette G Beck-Sickinger   +2 more
doaj   +1 more source

Neuropeptide Y regulates proliferation and apoptosis in granulosa cells in a follicular stage-dependent manner

Journal of Ovarian Research, 2020
Background The complex regulatory mechanism involved in ovarian follicular development is not completely understood. Neuronal neuropeptide Y (NPY) is involved in the regulation of feeding behavior, energy homeostasis, and reproduction behavior, while its
Yoko Urata, Reza Salehi, Patricia D. A. Lima, Yutaka Osuga, Benjamin K. Tsang   +4 more
doaj   +1 more source

Structure and function of the amygdaloid NPY system: NPY Y2 receptors regulate excitatory and inhibitory synaptic transmission in the centromedial amygdala

Brain Structure and Function, 2015
The amygdala is essential for generating emotional-affective behaviors. It consists of several nuclei with highly selective, elaborate functions. In particular, the central extended amygdala, consisting of the central amygdala (CEA) and the bed nucleus ...
J. Wood, D. Verma, G. Lach, P. Bonaventure, H. Herzog, G. Sperk, R. Tasan   +6 more
semanticscholar   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Synthesis, Characterization, and Electrochemical Properties of Tri‐ and Tetranuclear CoIII‐Oxo Complexes

European Journal of Inorganic Chemistry, EarlyView.
A series of three tetranuclear and two trinuclear Co(III) carboxylate complexes are synthesized and thoroughly spectroscopically and electrochemically characterized. The relative stability of the tetranuclear versus trinuclear complexes is investigated by density functional theory calculations, and the infrared and ultraviolet/visible spectra are ...
Timo Fockenberg, Niklas Sülzner, Hatem M. A. Amin, Christoph Wölper, Christof Hättig, Stephan Schulz   +5 more
wiley   +1 more source

NPY controls fear conditioning and fear extinction by combined action on Y1 and Y2 receptors

British Journal of Pharmacology, 2012
BACKGROUND AND PURPOSE Neuropeptide Y (NPY) and its receptors have been implicated in the control of emotional‐affective processing, but the mechanism is unclear.
D. Verma, R. O. Tasan, Herbert Herzog, G. Sperk   +3 more
semanticscholar   +1 more source

Unveiling Solvent‐Dependent Divergent Hydrogen Production Pathways during the Dehydrogenation of Formic Acid Using N,N′‐Iminopyridine Ruthenium(II) Complexes

European Journal of Inorganic Chemistry, EarlyView.
A readily available, efficient RuII catalyst mediates hydrogen production via formic acid dehydrogenation, via distinct, solvent‐dependent hydrogen production pathways. In water, catalyst robustness is observed, generating turnover numbers (TONs) of 13 791 under stepwise addition, while displaying sustained activity under continuous addition conditions
Thabiso Mphuti, Rotondwa Mphephu, Moegamat Joseph, Andrew J. Swarts   +3 more
wiley   +1 more source

Facilitation of neuropathic pain by the NPY Y1 receptor-expressing subpopulation of excitatory interneurons in the dorsal horn

Scientific Reports, 2019
Endogenous neuropeptide Y (NPY) exerts long-lasting spinal inhibitory control of neuropathic pain, but its mechanism of action is complicated by the expression of its receptors at multiple sites in the dorsal horn: NPY Y1 receptors (Y1Rs) on post ...
T. Nelson, Weisi Fu, R. Donahue, G. Corder, T. Hökfelt, R. Wiley, B. Taylor   +6 more
semanticscholar   +1 more source

mTOR–neuropeptide Y signaling sensitizes nociceptors to drive neuropathic pain

JCI Insight, 2022
Neuropathic pain is a refractory condition that involves de novo protein synthesis in the nociceptive pathway. The mTOR is a master regulator of protein translation; however, mechanisms underlying its role in neuropathic pain remain elusive.
Lunhao Chen, Yaling Hu, Siyuan Wang, Kelei Cao, Weihao Mai, Weilin Sha, Huan Ma, Ling-Hui Zeng, Zhen-Zhong Xu, Yong-Jing Gao, Shumin Duan, Yue Wang, Zhihua Gao   +12 more
doaj   +1 more source

Unraveling the Role of Ensheathing Cells and Perineural Fibroblasts in Olfactory Neurogenesis

Glia, EarlyView.
OECs are similar to satellite glial cells. OECs react to neuronal injury by promoting lipid metabolism, but do not proliferate. OECs reduce gap junctions upon neuronal injury. Perineural fibroblasts also contribute to the injury response. ABSTRACT During development and following injury‐induced neurogenesis, olfactory ensheathing cells (OECs) envelope ...
Katja Senf, Sandor Nietzsche, Martin Westermann, Eva M. Neuhaus   +3 more
wiley   +1 more source