Results 301 to 310 of about 197,106 (353)

A Subcellular Keap1-Nrf2 Disruption Strategy for Atopic Dermatitis Therapy. [PDF]

open access: yesJ Med Chem
Zhang Z   +7 more
europepmc   +1 more source

The Dual Roles of NRF2 in Cancer

Trends in Molecular Medicine, 2016
NRF2 has been traditionally considered as a tumor suppressor because its cytoprotective functions are deemed to be the main cellular defense mechanism against exogenous and endogenous insults, including xenobiotics and oxidative stress. However, several recent studies demonstrate that hyperactivation of the NRF2 pathway creates an environment that ...
Silvia Menegon   +2 more
exaly   +3 more sources

Nrf2 in adipocytes

Archives of Pharmacal Research, 2020
White adipocytes play a key role in maintaining whole body energy homeostasis by forming white adipose tissue (WAT). The impairment of WAT formation or WAT dysfunction is clearly associated with severe metabolic disorders. Mature adipocytes are derived from differentiated preadipocytes and are pivotal in energy storage and metabolism.
Zhendi, Wang   +8 more
openaire   +2 more sources

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