Results 161 to 170 of about 12,817 (217)

Development of a Norway Rat Hepacivirus Reporter for High-Throughput Quantification of Neutralising Antibodies

Kennedy MJ, Wolfisberg R, Thorselius CE, Collignon L, Lundsgaard EA, Nielsen L, Holmbeck K, Bukh J, Scheel TKH.   +8 more
europepmc   +1 more source

A Bibliometric Analysis of the HCV Drug-Resistant Majority and Minority Variants. [PDF]

Int J Environ Res Public Health
Immanuel OM, Fabiyi OT, Oshakbayev KP, Abuova G, Konysbekova A, Vattipally SB, Ali S, Abidi SH.   +7 more
europepmc   +1 more source

Live-Cell Imaging of Flaviviridae Family Virus Infections: Progress and Challenges. [PDF]

Viruses
Centofanti SM, Eyre NS.
europepmc   +1 more source

Hepatitis C virus NS3/4A protease cleaves SPG20, a key regulator of lipid droplet turnover, to promote lipid droplet formation. [PDF]

J Virol
Matsui C, Yuliandari P, Deng L, Abe T, Shoji I.   +4 more
europepmc   +1 more source

Pestivirus bovine viral diarrhea virus infection triggers lipophagy through the AMPK-PNPLA2/ATGL signaling pathway to promote viral replication. [PDF]

Autophagy
Ma Y, Fan W, Wang Y, Wang J, Li Y, Xia X, Zhu H, Lu Y, Hou G, Wang Y, Qiao X, Song H, Xu Y.   +12 more
europepmc   +1 more source

Potential Drug Interactions in Psychiatric Patients Undergoing Pangenotypic Therapy for Hepatitis C Virus Infection. [PDF]

Pharmaceuticals (Basel)
Dybowska D, Pawłowska M, Kozielewicz D.
europepmc   +1 more source

The architecture of membrane structures involved in hepatitis C virus genome replication revealed in close-to-native conditions by cryo-electron tomography

Sykora UM, O’ Sullivan TJ, Halfon Y, Fontana J, Harris M.   +4 more
europepmc   +1 more source

Characterizations of HCV NS5A replication complex inhibitors [PDF]

Virology, 2013
The hepatitis C virus NS5A protein is an established and clinically validated target for antiviral intervention by small molecules. Characterizations are presented of compounds identified as potent inhibitors of HCV replication to provide insight into structural elements that interact with the NS5A protein.
David R Langley, Chunfu Wang
exaly   +4 more sources

Correlation between NS5A Dimerization and Hepatitis C Virus Replication [PDF]

Journal of Biological Chemistry, 2012
Hepatitis C virus (HCV) is the main agent of acute and chronic liver diseases leading to cirrhosis and hepatocellular carcinoma. The current standard therapy has limited efficacy and serious side effects.
Philippe Gallay, Craig E Cameron, Suresh D Sharma   +2 more
exaly   +2 more sources

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Prevalence of NS5A resistance associated variants in NS5A inhibitor treatment failures and an effective treatment for NS5A-P32 deleted hepatitis C virus in humanized mice

Biochemical and Biophysical Research Communications, 2018
Patients with chronic hepatitis C virus (HCV) infection who have failed to respond to direct-acting antiviral (DAA) treatment often acquire drug resistance-associated variants (RAVs). The NS5A-P32 deletion (P32del) RAV confers potent resistance to NS5A inhibitors; therefore, patients who acquire this deletion are likely to fail to respond to DAA re ...
Mitsutaka Osawa, Masataka Tsuge, Michio Imamura   +2 more
exaly   +3 more sources