Results 111 to 120 of about 104,757 (302)
Access to Highly Functional and Polymerizable Carbonate‐Drug Conjugates
A generic protocol for drug‐functionalized and carbon dioxide‐based six‐membered cyclic carbonates has been developed. These functional carbonates can be designed for effective ring‐opening polymerization to forge polycarbonates that support a controllable amount of a given drug and additional functionality, opening up complementary strategies for ...
Wangyu Shi+5 more
wiley +1 more source
Celecoxib approved as NSAID with some concessions on class warning [PDF]
Jane L. Miller
openalex +1 more source
Quantification of 16 nonsteroidal anti‐inflammatory drugs using dried blood spot and LC–MS/HRMS was performed. By using a pharmacokinetic modelling and simulations, and according to the analytical performances of the method, detection windows for ibuprofen in ultra‐trail runners were proposed.
Mohammad Shafiq Mashal+4 more
wiley +1 more source
Nitric oxide‐releasing NSAIDs inhibit interleukin‐1β converting enzyme‐like cysteine proteases and protect endothelial cells from apoptosis induced by TNFα [PDF]
Fiorucci+10 more
openalex +1 more source
Tolerability of Topical NSAIDs in the Elderly [PDF]
Josie Evans, Thomas M. MacDonald
openalex +1 more source
Abstract Aims Atrial fibrillation (AF) is a frequent comorbidity in heart failure (HF). We analysed factors associated with new‐onset atrial fibrillation in patients with heart failure using linked real‐world UK data from primary and secondary care, along with findings from genome‐wide association studies. Methods and results Among 163 174 participants
Hiroyuki Yoshimura+6 more
wiley +1 more source
Experience with misoprostol therapy for NSAID gastropathy in children. [PDF]
Madlen Gazarian+4 more
openalex +1 more source
Immune Checkpoint Inhibitors and Cardiovascular Adverse Events
Abstract In the last years, we assisted to a tremendous increase in therapeutic options for the management of cancers, with immunotherapy at the forefront of this innovation. Immune checkpoint inhibitors (ICIs) have been developed to enhance the activity of the immune system against cancer cells (1) and the number of approvals for ICIs has rapidly ...
Maria Luisa De Perna+4 more
wiley +1 more source
Linking guideline‐directed medical therapy (GDMT) implementation and appropriate polypharmacy management in heart failure (HF). Polypharmacy can represent a barrier to the proper implementation of life‐prolonging GDMT for HF. A reasonable balance between the optimization of GDMT and avoiding inappropriate polypharmacy is mandatory in the contemporary ...
Davide Stolfo+27 more
wiley +1 more source