Results 91 to 100 of about 7,712 (169)

Targeting the nsp2 Cysteine Protease of Chikungunya Virus Using FDA Approved Library and Selected Cysteine Protease Inhibitors

Pathogens, 2019
Chikungunya virus (CHIKV) infection is one of the major public health concerns, leading thousands of cases every year in rural as well as urban regions of several countries worldwide, few to mention are India, Philippines, Indonesia, and also in American
Prateek Kumar, Deepak Kumar, Rajanish Giri   +2 more
doaj   +1 more source

Deciphering the Genetic Variation: A Comparative Analysis of Parental and Attenuated Strains of the QXL87 Vaccine for Infectious Bronchitis

Animals
The QXL87 live attenuated vaccine strain for infectious bronchitis represents the first approved QX type (GI-19 lineage) vaccine in China. This strain was derived from the parental strain CK/CH/JS/2010/12 through continuous passage in SPF chicken embryos.
Mengmeng Wang, Zongyi Bo, Chengcheng Zhang, Mengjiao Guo, Yantao Wu, Xiaorong Zhang   +5 more
doaj   +1 more source

Venezuelan equine encephalitis viral nsP2 protein (VEEV nsP2) [PDF]

Science-Business eXchange, 2014
openaire   +1 more source

Nodulation Signaling Pathway 1 and 2 Modulate Vanadium Accumulation and Tolerance of Legumes

Advanced Science
Vanadium (V) pollution potentially threatens human health. Here, it is found that nsp1 and nsp2, Rhizobium symbiosis defective mutants of Medicago truncatula, are sensitive to V.
Peng Liu, Xinfei Zhang, Lin Lin, Yanyan Cao, Xizhen Lin, Liaoliao Ye, Jun Yan, Huiling Gao, Jiangqi Wen, Kirankumar S. Mysore, Jinlong Liu   +10 more
doaj   +1 more source

Porcine deltacoronavirus nonstructural protein 2 inhibits type I and III IFN production by targeting STING for degradation

Veterinary Research
Porcine deltacoronavirus (PDCoV) is an enteropathogenic coronavirus that has been reported to use various strategies to counter the host antiviral innate immune response.
Xiqian Liu, Likai Ji, Yuqiang Cheng, Linghe Kong, Songhua Xie, Juan Yang, Jiaqi Chen, Zhaofei Wang, Jingjiao Ma, Hengan Wang, Yaxian Yan, Jianhe Sun   +11 more
doaj   +1 more source

Phosphorylation tunes strain-specific protein condensation during rotavirus replication organelle assembly

The EMBO Journal
In many viruses, intrinsically disordered proteins (IDPs) drive the formation of replicative organelles via liquid–liquid phase separation (LLPS). In species A rotaviruses, the disordered protein NSP5 forms condensates with NSP2, but its high sequence ...
Julia Acker, Xinyu Wang, Alonso J Pardal, Daniel Desirò, Tanushree Agarwal, Alice Colyer, Aidan Tollervey, Rob Scrutton, Cyril Haller, Lee Sherry, Kadi L Saar, Ksenia Fominykh, Margaret L L Y Johncock, Sai Hou Chong, Rosie Murray, Jamie Terry, Jeremy D Schmit, Antonio N Calabrese, Tuomas P J Knowles, Alexander Borodavka   +19 more
doaj   +1 more source

Arterivirus nsp2 Cysteine Proteinase

, 2013
Kikkert, Marjolein, Snijder, Eric J., Gorbalenya, Alexander E.   +2 more
openaire   +1 more source

The biological functions of PRRSV nonstructural protein NSP2 in viral infection and replication and its role in host regulatory mechanisms. [PDF]

Front Vet Sci
Zheng Z, Zhang M, Zhang Y, Zhang H, Ren J.   +4 more
europepmc   +1 more source

Analysis of Molecular Epidemiological Characteristics of Porcine Reproductive and Respiratory Syndrome Virus Type 2 in Shandong Province from 2023 to 2025. [PDF]

Vet Sci
Li Z, Wang X, Jiang L, Jin K, Feng Z, Xu J, Shen Y, Meng F, Qiu J, Li N, Liu S, Wang G.   +11 more
europepmc   +1 more source

PEX19 restricts porcine deltacoronavirus replication through farnesylation-dependent and -independent mechanisms. [PDF]

J Virol
Chen C, Su G, Wang Y, Xiong Y, Xiao W, Li Z, Fang L, Zhou Y, Xiao S.   +8 more
europepmc   +1 more source