Results 81 to 90 of about 12,594 (172)

ATP synthase subunit ATP5B interacts with TGEV Nsp2 and acts as a negative regulator of TGEV replication

Virulence
Coronavirus nonstructural protein 2 (Nsp2) is regarded as a virulence determinant and plays a critical role in virus replication, and innate immunity. Screening and identifying host cell proteins that interact with viral proteins is an effective way to ...
Yanan Wang, Aoying Sun, Yaru Guo, Lingxiang Xin, Yanping Jiang, Wen Cui, Jiaxuan Li, Yijing Li, Li Wang   +8 more
doaj   +1 more source

The role of porcine reproductive and respiratory syndrome (PRRS) virus structural and non-structural proteins in virus pathogenesis

, 2010
Porcine reproductive and respiratory syndrome (PRRS) is an economically devastating viral disease affecting the swine industry worldwide. The etiological agent, PRRS virus (PRRSV), possesses a RNA viral genome with nine open reading frames (ORFs).
Albina, Arrese, Carl A. Gagnon, Cavanagh, de Haan, de Vries, de Vries, Dea, den Boon, den Boon, Duan, Faaberg, Ferrin, Fitter, Gagnon, Hasegawa, Keffaber, Lee, Loula, Magar, Mardassi, Mardassi, McNabb, Meulenberg, Nedzad Music, Nelsen, Nelson, Pirzadeh, Plagemann, Plana Duran, Reitter, Roossinck, Seuberlich, Sincock, Snijder, Snijder, Suarez, Sur, Sur, van Dinten, van Dinten, van Marle, van Nieuwstadt, Vennema, Wassenaar, Wootton, Wootton   +46 more
core   +1 more source

Association of rotavirus viroplasms with microtubules through NSP2 and NSP5

Memorias do Instituto Oswaldo Cruz, 2006
Rotavirus replication and virus assembly take place in electrodense spherical structures known as viroplasms whose main components are the viral proteins NSP2 and NSP5.
Claudio Cabral-Romero, Luis Padilla-Noriega   +1 more
doaj   +1 more source

Differential unfolded protein response during Chikungunya and Sindbis virus infection: CHIKV nsP4 suppresses eIF2α phosphorylation [PDF]

, 2013
10.1186/1743-422X-10-36Virology ...
Ng, M.-L., Rathore, A.P.S., Vasudevan, S.G.   +2 more
core   +2 more sources

Molecular Characterization of the Porcine Group A Rotavirus NSP2 and NSP5/6 Genes from São Paulo State, Brazil, in 2011/12

The Scientific World Journal, 2013
Rotaviruses are responsible for the acute diarrhea in various mammalian and avian species. The nonstructural proteins NSP2 and NSP5 are involved in the rotavirus replication and the formation of viroplasm, cytoplasmic inclusion bodies within which new ...
Bruna Rocha Passos Barbosa, Nara Thiers Cacciatori Galleti Bernardes, Laila Andreia Rodrigues Beserra, Fábio Gregori   +3 more
doaj   +1 more source

Chikungunya virus: an update on the biology and pathogenesis of this emerging pathogen [PDF]

, 2017
Re-emergence of chikungunya virus, a mosquito-transmitted pathogen, is of serious public health concern. In the past 15 years, after decades of infrequent, sporadic outbreaks, the virus has caused major epidemic outbreaks in Africa, Asia, the Indian ...
Burt, Felicity J, Chen, Weiqiang, Herrero, Lara J, Kohl, Alain, Lenschow, Deborah J, Mahalingam, Suresh, Merits, Andres, Miner, Jonathan J, Ng, Lisa FP, Rudd, Penny A, Schnettler, Esther, Taylor, Adam, Zaid, Ali   +12 more
core   +1 more source

Porcine reproductive and respiratory syndrome virus nonstructural protein 2 promotes the autophagic degradation of adaptor protein SH3KBP1 to antagonize host innate immune responses by enhancing K63-linked polyubiquitination of RIG-I.

PLoS Pathogens
Non-structural protein 2 (NSP2) of PRRSV is highly variable and plays crucial roles in the virus's life cycle. To elucidate the function of NSP2 during PRRSV infection, we identified SH3KBP1 as an NSP2-interacting host protein using mass spectrometry ...
Jiaoyang Li, Jing Zhang, Pu Sun, Jian Wang, Guoxiu Li, Zhanding Cui, Dong Li, Hong Yuan, Tao Wang, Kun Li, Xingwen Bai, Zhixun Zhao, Yimei Cao, Xueqing Ma, Pinghua Li, Yuanfang Fu, Huifang Bao, Zaixin Liu, Shuqi Xiao, Xinglong Wang, Zengjun Lu   +20 more
doaj   +1 more source

Targeting the nsp2 Cysteine Protease of Chikungunya Virus Using FDA Approved Library and Selected Cysteine Protease Inhibitors

Pathogens, 2019
Chikungunya virus (CHIKV) infection is one of the major public health concerns, leading thousands of cases every year in rural as well as urban regions of several countries worldwide, few to mention are India, Philippines, Indonesia, and also in American
Prateek Kumar, Deepak Kumar, Rajanish Giri   +2 more
doaj   +1 more source

Lunar Crater Observation and Sensing Satellite (LCROSS) Instrument Calibration Summary [PDF]

, 2010
This document describes the calibration of the LCROSS instruments. It will be released to the public via the Planetary Data System. We need a quick review, if possible, because the data has been delivered to the PDS, and this document is needed to ...
Colaprete, Anthony, Shirley, Mark H., Smith, Kimberly Ennico, Wooden, Diane H.   +3 more
core   +1 more source

Rotavirus NSP2: A Master Orchestrator of Early Viral Particle Assembly

Viruses
Rotaviruses (RVs) are 11-segmented, double-stranded (ds) RNA viruses and important causes of acute gastroenteritis in humans and other animal species.
Sarah L. Nichols, Cyril Haller, Alexander Borodavka, Sarah M. Esstman   +3 more
doaj   +1 more source