Results 81 to 90 of about 4,180 (199)

CBSX2 is required for the efficient oxidation of chloroplast redox‐regulated enzymes in darkness

open access: yesPlant Direct, 2023
Thiol/disulfide‐based redox regulation in plant chloroplasts is essential for controlling the activity of target proteins in response to light signals.
Yonghong Li   +4 more
doaj   +1 more source

The Highly Conserved Cys95 Residue of Fructose‐1,6‐Bisphosphatase 1 Mediates the pH‐Driven Structure and Activity of the Enzyme and Photosynthesis

open access: yesPlant, Cell &Environment, Volume 48, Issue 9, Page 6941-6951, September 2025.
ABSTRACT In Arabidopsis, exposure to microbial volatile compounds promotes thiol reduction of the Cys95 residue of the photosynthetic enzyme fructose‐1,6‐bisphosphatase (cFBP1). Although highly conserved in plants, the Cys95 function still remains unknown. We characterised recombinant wild‐type (WT) cFBP1 and a variant (C95S) in which the Cys95 residue
Samuel Gámez‐Arcas   +9 more
wiley   +1 more source

Spontaneous and pharmacologically induced hypothermia protect mice against endotoxic shock

open access: yesBritish Journal of Pharmacology, Volume 182, Issue 12, Page 2621-2641, June 2025.
Background and Purpose Despite the well‐known occurrence of hypothermia during sepsis, its underlying biological nature and adaptive value remain debated. Experimental Approach Using indirect calorimetry, telemetry, thermal gradient studies and pharmacological studies, we examined the thermal and metabolic responses of mice treated with a shock ...
Arely Tinajero   +7 more
wiley   +1 more source

Thiol-based redox control of enzymes involved in the tetrapyrrole biosynthesis pathway

open access: yesFrontiers in Plant Science, 2013
The last decades of research brought substantial insights into tetrapyrrole biosynthetic pathway in photosynthetic organisms. Almost all genes have been identified and roles of seemingly all essential proteins, leading to the synthesis of heme, siroheme,
Andreas Sven Richter, Bernhard eGrimm
doaj   +1 more source

Threonine and tyrosine kinase (TTK) mRNA and protein expression in breast cancer; prognostic significance in the neoadjuvant setting

open access: yesHistopathology, Volume 86, Issue 6, Page 916-932, May 2025.
This study investigates threonine and tyrosine kinase (TTK) expression in pre‐ and post‐neoadjuvant chemotherapy breast cancer patients. TTK mRNA expression was elevated in breast cancer tissues, predicting reduced survival. Notably, TTK protein expression in neoadjuvant chemotherapy‐treated breast cancer patients was up‐regulated post‐therapy and ...
Abrar Ashi   +5 more
wiley   +1 more source

Nitrogen Assimilation Plays a Role in Balancing the Chloroplastic Glutathione Redox Potential Under High Light Conditions

open access: yesPlant, Cell &Environment, Volume 48, Issue 5, Page 3559-3572, May 2025.
ABSTRACT Nitrate reduction requires reducing equivalents produced by the photosynthetic electron transport chain. Therefore, it has been suggested that nitrate assimilation provides a sink for electrons under high light conditions. We tested this hypothesis by monitoring photosynthetic efficiency and the chloroplastic glutathione redox potential (chl ...
Gal Gilad   +8 more
wiley   +1 more source

Regulatory and retrograde signaling networks in the chlorophyll biosynthetic pathway

open access: yesJournal of Integrative Plant Biology, Volume 67, Issue 4, Page 887-911, April 2025.
This review summarizes the regulatory mechanisms that underlie chlorophyll synthesis, including (1) factors that control the activity and stability of tetrapyrrole biosynthesis enzymes, (2) transcriptional and post‐translational regulation of the tetrapyrrole biosynthesis pathway, and (3) the complex roles of tetrapyrrole‐mediated retrograde signaling ...
Yuhong Li   +6 more
wiley   +1 more source

Cellodextrin Metabolism and Phosphotransferase System‐Catalyzed Uptake in Enterococcus faecalis

open access: yesMolecular Microbiology, Volume 123, Issue 4, Page 378-391, April 2025.
In an infectious context, β‐glucoside metabolism is highly induced in Enterococcus faecalis. Our work demonstrates that this bacterium possesses a network of multiple PTS transporters dedicated to the transport of cellobiose and cellodextrins. The genes encoding the proteins involved in this metabolism are clustered within a single locus in the E ...
Victor Combret   +8 more
wiley   +1 more source

data for NtrC

open access: yes, 2001
movie [http://bioinfo.mbb.yale.edu/molmovdb; W. G. Krebs, M. Gerstein, Nucleic Acids Res. 28, 1665 (2000)] is also available at www.sciencemag. org/cgi/content/full/291/5512/2429/DC1. 27.
Brian F. Volkman   +4 more
core  

Broad spectrum pro-quorum-sensing molecules as inhibitors of virulence in vibrios.

open access: yesPLoS Pathogens, 2012
Quorum sensing (QS) is a bacterial cell-cell communication process that relies on the production and detection of extracellular signal molecules called autoinducers. QS allows bacteria to perform collective activities.
Wai-Leung Ng   +4 more
doaj   +1 more source

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