Results 1 to 10 of about 33,744 (220)

Interactions of Entamoeba histolytica peroxiredoxin with the TLR4/MD2 complex trigger ferroptosis in host cells [PDF]

Microbiology Spectrum
Amoebiasis is a critical global parasitic disease caused by Entamoeba histolytica. It includes amoebic colitis and extraintestinal abscesses. E. histolytica peroxiredoxin (EhPrx) is a crucial antioxidant enzyme that maintains redox homeostasis and ...
Ruixue Zhou, Wenjie Li, Qingtong Zhou, Yanqing Zhao, Xia Li, Hongze Zhang, Dai Dong, Wenwen Jing, Hiroshi Tachibana, Meng Feng, Gang Fu, Xunjia Cheng   +11 more
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Knockout Mouse Models for Peroxiredoxins [PDF]

Antioxidants, 2020
Peroxiredoxins (PRDXs) are members of a highly conserved peroxidase family and maintain intracellular reactive oxygen species (ROS) homeostasis. The family members are expressed in most organisms and involved in various biological processes, such as ...
Young Jae Lee
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Low levels of peroxiredoxins are associated with high iron content and lipid peroxidation in seminal plasma from asthenozoospermic infertile men

Endocrine and Metabolic Science, 2023
Asthenospermia is a common cause of male infertility refers to semen samples with spermatozoa that move slowly or immotile. Recent research has implicated oxidative stress-induced ferroptosis in asthenospermia's pathophysiology.
Lamia A. Almashhedy, Hussein A. Fadhil, Abdul Razzaq S. Alsalman, Hawraa Saad Al-Kawaz, Abdulsamie Hassan Alta'ee, Alaa Tariq Al-Hassnawi, Asad M. Hadwan, Mahmoud Hussein Hadwan   +7 more
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Conoidin A, a Covalent Inhibitor of Peroxiredoxin 2, Reduces Growth of Glioblastoma Cells by Triggering ROS Production

Cells, 2023
Compounds that cause oxidative stress have recently gained considerable interest as potential anticancer treatment modalities. Nevertheless, their efficiency may be diminished by the antioxidant systems often upregulated in cancer cells.
Monika Szeliga, Radosław Rola
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Voluntary Exercise-Mediated Protection in TNBS-Induced Rat Colitis: The Involvement of NETosis and Prdx Antioxidants

Antioxidants, 2023
Inflammatory bowel diseases (IBDs) are autoimmune disorders of the gut. It is increasingly clear that voluntary exercise (VE) may exert protection against IBDs, but the exact background mechanism needs to be elucidated.
Nikoletta Almási, Szilvia Török, Amin Al-awar, Médea Veszelka, László Király, Denise Börzsei, Renáta Szabó, Csaba Varga   +7 more
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Specificity of Human Sulfiredoxin for Reductant and Peroxiredoxin Oligomeric State

Antioxidants, 2021
Human peroxiredoxins (Prx) are a family of antioxidant enzymes involved in a myriad of cellular functions and diseases. During the reaction with peroxides (e.g., H2O2), the typical 2-Cys Prxs change oligomeric structure between higher order (do)decamers ...
Tom E. Forshaw, Julie A. Reisz, Kimberly J. Nelson, Rajesh Gumpena, J. Reed Lawson, Thomas J. Jönsson, Hanzhi Wu, Jill E. Clodfelter, Lynnette C. Johnson, Cristina M. Furdui, W. Todd Lowther   +10 more
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Essential Roles of Peroxiredoxin IV in Inflammation and Cancer

Molecules, 2022
Peroxiredoxin IV (Prx4) is a 2-Cysteine peroxidase with ubiquitous expression in human tissues. Prx4 scavenges hydrogen peroxide and participates in oxidative protein folding in the endoplasmic reticulum.
Pratik Thapa, Na Ding, Yanning Hao, Aziza Alshahrani, Hong Jiang, Qiou Wei   +5 more
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Expression changes of superoxide dismutase 2 and peroxiredoxin 6 in asthenospermia and their correlation with sperm motility

Di-san junyi daxue xuebao, 2021
Objective To explore the damaging effects of reactive oxygen species (ROS) on spermatozoa, and investigate the expression changes of superoxide dismutase 2 (SOD2) and peroxiredoxin 6 (PRDX6) in spermatozoa of asthenospermia patients, so as to analyze ...
YANG Zihan, YANG Zihan, HAO Xiaoling, HAO Xiaoling, WANG Hong, HUANG Run, MENG Jiangping   +6 more
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Expression of thioredoxin 1 and peroxiredoxins in squamous cervical carcinoma and its predictive role in NACT

BMC Cancer, 2019
Background This study aims to investigate the expression of thioredoxin 1, peroxiredoxin 1 and peroxiredoxin 2 in bulky cervical squamous carcinoma and its predictive role in cisplatin-based neoadjuvant chemotherapy.
Haiyan Zhu, Xuejiao Tao, Lulu Zhou, Bo Sheng, Xuejie Zhu, Xueqiong Zhu   +5 more
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Hyperglycemia decreases preoxiredoxin-2 expression in a middle cerebral artery occlusion model

Laboratory Animal Research, 2017
Diabetes is a major risk factor for stroke and is also associated with worsened outcomes following a stroke. Peroxiredoxin-2 exerts potent neuroprotective effects against oxidative stress.
Phil-Ok Koh
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