Results 11 to 20 of about 32,727 (216)
Peroxiredoxin, Senescence, and Cancer
Cells, 2022 Peroxiredoxins are multifunctional enzymes that play a key role in protecting cells from stresses and maintaining the homeostasis of many cellular processes.
Mengyao Wu +5 more
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Peroxiredoxins in Parasites [PDF]
Antioxidants & Redox Signaling, 2012 Parasite survival and virulence relies on effective defenses against reactive oxygen and nitrogen species produced by the host immune system. Peroxiredoxins (Prxs) are ubiquitous enzymes now thought to be central to such defenses and, as such, have potential value as drug targets and vaccine antigens.Plasmodial and kinetoplastid Prx systems are the ...
Michael C, Gretes +2 more
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Hyperglycemia decreases preoxiredoxin-2 expression in a middle cerebral artery occlusion model
Laboratory Animal Research, 2017 Diabetes is a major risk factor for stroke and is also associated with worsened outcomes following a stroke. Peroxiredoxin-2 exerts potent neuroprotective effects against oxidative stress.
Phil-Ok Koh
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eLife, 2020 Peroxiredoxins are H2O2 scavenging enzymes that also carry out H2O2 signaling and chaperone functions. In yeast, the major cytosolic peroxiredoxin, Tsa1 is required for both promoting resistance to H2O2 and extending lifespan upon caloric restriction. We
Friederike Roger +14 more
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CBSX2 is required for the efficient oxidation of chloroplast redox‐regulated enzymes in darkness
Plant Direct, 2023 Thiol/disulfide‐based redox regulation in plant chloroplasts is essential for controlling the activity of target proteins in response to light signals.
Yonghong Li +4 more
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Haematologica, 2011 Background β-thalassemic syndromes are inherited red cell disorders characterized by severe ineffective erythropoiesis and increased levels of reactive oxygen species whose contribution to β-thalassemic anemia is only partially understood.Design and ...
Lucia De Franceschi +9 more
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Molecules, 2015 Glutaredoxin (Grx), peroxiredoxin (Prx), and thioredoxin (Trx) are redoxin family proteins that catalyze different types of chemical reactions that impact cell growth and survival through functionally distinct intracellular pathways.
Aulma R. Parker +10 more
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mBio, 2021 Aspergillus fumigatus is an important fungal pathogen that causes allergic reactions but also life-threatening infections. One of the most abundant A. fumigatus proteins is Asp f3. This peroxiredoxin is a major fungal allergen and known for its role as a
Victor Brantl +10 more
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Frontiers in Aging Neuroscience, 2019 Similar to humans, the normal aged rat population is not homogeneous in terms of cognitive function. Two distinct subpopulations of aged Sprague–Dawley rats can be identified on the basis of spatial memory performance in the hole-board paradigm.
Jana Lubec +6 more
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Applied Sciences, 2020 In this paper, a fluorescence resonance energy transfer (FRET)-based sensor for ultra-sensitive detection of H2O2 was developed by utilizing the unique enzymatic properties of peroxiredoxin (Prx) to H2O2. Cyan and yellow fluorescent protein (CFP and YFP)
Haijun Yu +4 more
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