Results 31 to 40 of about 32,727 (216)

Antiviral Function of NKEF against VHSV in Rainbow Trout

open access: yesBiology, 2021
Natural killer enhancing factor (NKEF) belongs to the peroxiredoxin family of proteins, a group of antioxidants that has been extensively studied in mammals. Recently, we identified NKEF in the immunoprecipitated proteome of rainbow trout red blood cells
Veronica Chico   +6 more
doaj   +1 more source

Fish Peroxiredoxins and Their Role in Immunity [PDF]

open access: yesBiology, 2015
Peroxiredoxins (Prxs) are a family of antioxidant enzymes that protect cells from oxidative damage. In addition, Prxs may act as modulators of inflammation, protect against cell death and tumour progression, and facilitate tissue repair after damage. The most studied roles of Prx1 and Prx2 are immunological.
Yulema Valero   +4 more
openaire   +5 more sources

Signals Getting Crossed in the Entanglement of Redox and Phosphorylation Pathways: Phosphorylation of Peroxiredoxin Proteins Sparks Cell Signaling

open access: yesAntioxidants, 2019
Reactive oxygen and nitrogen species have cell signaling properties and are involved in a multitude of processes beyond redox homeostasis. The peroxiredoxin (Prdx) proteins are highly sensitive intracellular peroxidases that can coordinate cell signaling
John J. Skoko   +2 more
doaj   +1 more source

Peroxiredoxins and their expression in ependymomas

open access: yesJournal of Clinical Pathology, 2012
AimsPeroxiredoxins I–VI (Prxs) have recently been shown to have a role in the tumorigenesis of astrocytic brain tumours. In some tumour types they are associated with Nrf2 (transcription factor NF-E2-related factor), a sensor of oxidative stress, and DJ-1 (also known as PARK7), a protein known to stabilise Nrf2.MethodsWe investigated the ...
Mikkonen Eloise   +8 more
openaire   +3 more sources

Synechococcus sp. PCC7002 Uses Peroxiredoxin to Cope with Reactive Sulfur Species Stress

open access: yesmBio, 2022
Cyanobacteria are a widely distributed group of microorganisms in the ocean, and they often need to cope with the stress of reactive sulfur species, such as sulfide and sulfane sulfur.
Daixi Liu   +10 more
doaj   +1 more source

Overview on Peroxiredoxin

open access: yesMolecules and Cells, 2016
Peroxiredoxins (Prxs) are a very large and highly conserved family of peroxidases that reduce peroxides, with a conserved cysteine residue, designated the "peroxidatic" Cys (CP) serving as the site of oxidation by peroxides (Hall et al., 2011; Rhee et al., 2012).
openaire   +3 more sources

Peroxiredoxins in colorectal neoplasms.

open access: yesHistology and histopathology, 2010
Peroxiredoxins (Prxs) are novel group proteins with efficient antioxidant capacity, and some of them also have effects on cell proliferation, differentiation, apoptosis, and chemotherapy and radiotherapy resistance. Altogether six distinct Prxs expressions were investigated in histological samples of colorectal neoplasm and the distant normal tissues ...
Wu, X.Y., Fu, X.Z., Wang, X.H.
openaire   +3 more sources

Cancer-Associated Function of 2-Cys Peroxiredoxin Subtypes as a Survival Gatekeeper

open access: yesAntioxidants, 2018
Cancer cells are abnormal cells that do not comply with tissue homeostasis but undergo uncontrolled proliferation. Such abnormality is driven mostly by somatic mutations on oncogenes and tumor suppressors.
Sang Won Kang   +2 more
doaj   +1 more source

The Human 2-Cys Peroxiredoxins form Widespread, Cysteine-Dependent- and Isoform-Specific Protein-Protein Interactions

open access: yesAntioxidants, 2021
Redox signaling is controlled by the reversible oxidation of cysteine thiols, a post-translational modification triggered by H2O2 acting as a second messenger.
Loes van Dam   +6 more
doaj   +1 more source

The role of peroxiredoxins in cancer

open access: yesMolecular and Clinical Oncology, 2017
Peroxiredoxins (PRDXs) are a ubiquitously expressed family of small (22-27 kDa) non-seleno peroxidases that catalyze the peroxide reduction of H2O2, organic hydroperoxides and peroxynitrite. They are highly involved in the control of various physiological functions, including cell growth, differentiation, apoptosis, embryonic development, lipid ...
NICOLUSSI, Arianna   +4 more
openaire   +4 more sources

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