Results 21 to 30 of about 32,727 (216)
The effect of exogenous peroxiredoxin 6 on morphofunctional state of isolated rat kidney
Вестник трансплантологии и искусственных органов, 2021 Objective: to investigate the role of peroxiredoxin 6 (PRX6) in preserving the morphofunctional state of ischemic isolated kidney during perfusion.Materials and methods. The model of an isolated perfused rat kidney was used.
A. E. Gordeeva +2 more
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Peroxiredoxins in Neurodegenerative Diseases [PDF]
Antioxidants, 2020 Substantial evidence indicates that oxidative/nitrosative stress contributes to the neurodegenerative diseases. Peroxiredoxins (PRDXs) are one of the enzymatic antioxidant mechanisms neutralizing reactive oxygen/nitrogen species. Since mammalian PRDXs were identified 30 years ago, their significance was long overshadowed by the other well-studied ROS ...
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Meat and Muscle Biology, 2023 The development of fresh meat quality is dictated by biochemical changes during the perimortem and postmortem period. Lipid and protein oxidation in postmortem skeletal muscle and meat products is detrimental to product quality.
Brian M Patterson +3 more
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The Peroxiredoxin Repair Proteins [PDF]
, 2007 Sulfiredoxin and sestrin are cysteine sulfinic acid reductases that selectively reduce or repair the hyperoxidized forms of typical 2-Cys peroxiredoxins within eukaryotes. As such these enzymes play key roles in the modulation of peroxide-mediated cell signaling and cellular defense mechanisms. The unique structure of sulfiredoxin facilitates access to
Thomas J, Jönsson, W Todd, Lowther
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Antioxidants, 2023 Non-small cell lung cancer (NSCLC), the most common type of lung cancer, etiologically associates with tobacco smoking which mechanistically contributes to oxidative stress to facilitate the occurrence of mutations, oncogenic transformation and ...
Yanning Hao +7 more
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Measurement of Peroxiredoxin Activity [PDF]
Current Protocols in Toxicology, 2011 AbstractPeroxiredoxins are cysteine‐dependent peroxidases that react with hydrogen peroxide, larger hydroperoxide substrates, and peroxynitrite. Protocols are provided to measure Prx activity with peroxide by (1) a coupled reaction with NADPH, thioredoxin reductase, and thioredoxin, (2) the direct monitoring of thioredoxin oxidation, (3) competition ...
Kimberly J, Nelson, Derek, Parsonage
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Frontiers in Plant Science, 2013 Photosynthesis, the primary source of biomass and oxygen into the biosphere, involves the transport of electrons in the presence of oxygen and, therefore, chloroplasts constitute an important source of reactive oxygen species (ROS), including hydrogen ...
Leonor ePuerto-Galán +8 more
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The Role of Thioredoxin/Peroxiredoxin in the β-Cell Defense Against Oxidative Damage
Frontiers in Endocrinology, 2021 Oxidative stress is hypothesized to play a role in pancreatic β-cell damage, potentially contributing to β-cell dysfunction and death in both type 1 and type 2 diabetes.
Jennifer S. Stancill, John A. Corbett
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Urate hydroperoxide oxidizes human peroxiredoxin 1 and peroxiredoxin 2 [PDF]
Journal of Biological Chemistry, 2017 Urate hydroperoxide is a product of the oxidation of uric acid by inflammatory heme peroxidases. The formation of urate hydroperoxide might be a key event in vascular inflammation, where there is large amount of uric acid and inflammatory peroxidases.
Larissa A C, Carvalho +7 more
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Piecing Together How Peroxiredoxins Maintain Genomic Stability
Antioxidants, 2018 Peroxiredoxins, a highly conserved family of thiol oxidoreductases, play a key role in oxidant detoxification by partnering with the thioredoxin system to protect against oxidative stress.
James D. West +4 more
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