Results 61 to 70 of about 13,748 (197)

Molecular pathology of phyllodes tumours of the breast—much more than MED12

Histopathology, EarlyView.
Phyllodes tumours can develop from fibroadenomas bearing MED12 variants by the development of pTERT alterations (“MED12 pathway”) or de novo (“MED12 independent pathway”). Grade progression is associated with increasing genetic complexity including cancer driver gene aberrations. Molecular alterations can be useful in assigning grade and distinguishing
Jia‐Min B Pang, Kylie L Gorringe, Puay Hoon Tan, Stephen B Fox   +3 more
wiley   +1 more source

Evaluation of NTRK Gene Fusion by Five Different Platforms in Triple-Negative Breast Carcinoma

Frontiers in Molecular Biosciences, 2021
Triple-negative breast carcinoma (TNBC) is an aggressive disease that has a poor prognosis since it lacks effective treatment methods. Neurotrophic tyrosine receptor kinase (NTRK) fusion genes are excellent candidates for targeted RTK inhibitor therapies
Shafei Wu, Xiaohua Shi, Xinyu Ren, Kaimi Li, Junyi Pang, Zhiyong Liang   +5 more
doaj   +1 more source

Elliptic flow in proton-proton collisions at 7 TeV

, 2010
The angular correlations measured in proton-proton collisions at 7 TeV are decomposed into contributions from back to back emission and elliptic flow.
D. d’Enterria, I. Bautista, J. Casalderrey-Solana, J. Liao, J.Y. Ollitrault, L. Cunqueiro, M. Luzum, N. Borghini, N. Borghini, N. Borghini, P. Bożek, Piotr Bożek, S.K. Prasad, V. Khachatryan, V. Khachatryan, Z. Chajecki   +15 more
core   +1 more source

Distributed data mining in grid computing environments [PDF]

, 2007
The official published version of this article can be found at the link below.The computing-intensive data mining for inherently Internet-wide distributed data, referred to as Distributed Data Mining (DDM), calls for the support of a powerful Grid with ...
Cannataro, Cannataro, Fernandez-Baca, Kevin Lü, Kwok, Ping Luo, Qing He, Zhongzhi Shi   +7 more
core   +1 more source

Precision medicine in cutaneous melanoma—A comprehensive review

Journal of the European Academy of Dermatology and Venereology, EarlyView.
Precision medicine tailors treatment to each patient, beginning with detailed diagnostics. In melanoma, it has advanced considerably: Some methods are in practice and guidelines, while others are commercially available but not routine. This review highlights current and emerging approaches, including molecular profiling, imaging, biomarkers and AI ...
Markus Reitmajer, Lukas Flatz
wiley   +1 more source

Prevalence of neurotrophic tropomyosin receptor kinase (NTRK) fusion gene positivity in patients with solid tumors in Japan

Cancer Medicine
Background Members of the neurotrophic tropomyosin receptor kinase (NTRK) gene family, NTRK1, NTRK2, and NTRK3 encode TRK receptor tyrosine kinases. Intra‐ or inter‐chromosomal gene rearrangements produce NTRK gene fusions encoding fusion proteins which ...
Eiji Nakata, Tatsunori Osone, Toru Ogawa, Tomoyuki Taguchi, Kana Hattori, Shinji Kohsaka   +5 more
doaj   +1 more source

Case report: Acquired neurotrophic tyrosine receptor kinase inhibitor resistance in a patient with pancreatic neuroendocrine carcinoma receiving entrectinib

Frontiers in Oncology, 2023
Pancreatic neuroendocrine carcinoma (panNEC) is a rare disease. The rearrangements of neurotrophic tropomyosin receptor kinase (NTRK) genes are oncogenic.
Wen-Chi Wu, Wen-Chi Wu, Wen-Chi Wu, Wen-Chi Wu, Ming-Huang Chen, Ming-Huang Chen, Ming-Huang Chen   +6 more
doaj   +1 more source

Search for long-lived particles with the ATLAS detector [PDF]

, 2014
Several scenarios beyond the Standard Model predict heavy long-lived particles as a result of a kinematic constraint, a conserved quantum number or a weak coupling.
Yamamoto, Shimpei
core  

Open-charm production as a function of charged particle multiplicity in pp collisions at \sqrt{s}=7 TeV with ALICE

, 2013
Heavy quarks (charm and beauty) are an effective tool to investigate the properties of the Quark-Gluon Plasma created in heavy-ion collisions as they are produced in initial hard scattering processes and as they experience all the stages of the medium ...
Bala, Renu
core   +1 more source

The spectrum of breast in situ papillary carcinomas with invasion and invasive breast carcinomas with papillary features: an overview of histological subtypes and diagnostic challenges

Histopathology, Volume 88, Issue 4, Page 747-768, March 2026.
Invasive breast carcinomas with papillary features (IBCP) comprise diverse subtypes with variable architecture, histopathology, and clinical behaviour. This review outlines evolving classification, diagnostic criteria, and treatment implications, highlighting challenges in distinguishing in situ from invasive lesions. Standardised diagnostic approaches
Emad A Rakha, Puay Hoon Tan, Wendy A Raymond   +2 more
wiley   +1 more source