Results 171 to 180 of about 9,316 (206)

KDM3B promotes neural invasion in colorectal cancer through TrkA upregulation by inhibiting H3K9 dimethylation. [PDF]

iScience
Li J, Sun S, Wang X, Li Y, Zhang H, Fu X, Zhao X, Chen G.   +7 more
europepmc   +1 more source

Osimertinib with chemotherapy in advanced non-small cell lung cancer with vaginal metastasis harboring <i>EGFR</i> exon 21 L858R and <i>NTRK1</i> exon 16 V679M mutations: a case report with prolonged progression-free survival. [PDF]

Gynecol Pelvic Med
Chen Q, Liu Y, Zhang H, He X.
europepmc   +1 more source

Pathology-guided enrichment of targetable gene rearrangements in BRAF wild-type papillary thyroid carcinoma. [PDF]

Sci Rep
Jin M, Kim CA, Jeon MJ, Lee YM, Sung TY, Kim TY, Song DE, Kim WG.   +7 more
europepmc   +1 more source

Tumor-infiltrating T Lymphocytes Recognize Thyroid-specific Proteins and Neo-antigens in Follicular Cell-derived Thyroid Cancers.

J Clin Endocrinol Metab
Garza B, Calhoun J, Norman PJ, Cline N, Kichula KM, Farias TDJ, Sams S, Boorgula MP, Danhorn T, Haugen BR, French JD.   +10 more
europepmc   +1 more source

Rearrangement of NTRK1 oncogene in papillary thyroid carcinoma

Neuroendocrinology Letters, 2007
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Oncogenic rearrangements of the NTRK1/NGF receptor

Cancer Letters, 2006
The NTRK1 gene encodes the high affinity receptor for Nerve Growth Factor, and its action regulates neural development and differentiation. Deregulation of NTRK1 activity is associated with several human disorders. Loss of function mutations causes the genetic disease congenital insensitivity to pain with anhidrosis (CIPA).
Marco Alessandro Pierotti, Angela Greco
exaly   +3 more sources

NTRK1/TrkA Activation Overrides the G2/M-Checkpoint upon Irradiation

Cancers, 2021
High expression of the receptor tyrosine kinase TrkA/NTRK1 is associated with a favorable outcome in several solid tumors of childhood including neuroblastoma.
Alexander Schramm, Sebastian Oeck, Aashish Soni   +2 more
exaly   +2 more sources

The presence of Y674/Y675 phosphorylated NTRK1 via TP53 repression of PTPN6 expression as a potential prognostic marker in neuroblastoma [PDF]

Human Pathology, 2019
The tumor suppressor TP53 promotes nerve growth factor receptor (NTRK1) -Y674/Y675 phosphorylation (NTRK1-pY674/pY675) via repression of the NTRK1 phosphatase PTPN6 in a ligand-independent manner, resulting in suppression of breast cancer cell ...
Nj Sébire, Jack Barton, Alexander Virasami   +2 more
exaly   +2 more sources

NTRK1/TrkA Signaling in Neuroblastoma Cells Induces Nuclear Reorganization and Intra-Nuclear Aggregation of Lamin A/C

Cancers, 2021
(1) Background: Neuroblastomas (NBs) are the most common extracranial solid tumors of children. The amplification of the Myc-N proto-oncogene (MYCN) is a major driver of NB aggressiveness, while high expression of the neurotrophin receptor NTRK1/TrkA is ...
Alexander Schramm, Sebastian Oeck, Thilo Bracht   +2 more
exaly   +2 more sources