Results 1 to 10 of about 1,299 (166)

Metabolomic Insights Into the Impact of a Maternal Western-Style Diet and Leptin Supplementation During Suckling on Adult Rat Offspring. [PDF]

FASEB J
Plasma metabolites in adult offspring reflecting metabolic programming during critical developmental windows. ABSTRACT Perinatal nutrition influences offspring metabolic phenotype and obesity risk. This study examines how a maternal obesogenic diet and offspring's leptin supplementation during suckling affect the metabolome in offspring adulthood ...
Pomar CA, Martin-Chamorro RA, Zouhar P, Castillo P, Cajka T, Kopecky J, Palou A, Palou M, Picó C.   +8 more
europepmc   +2 more sources

Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal-Weight Rats, Prevented by Perinatal Leptin Intake. [PDF]

Mol Nutr Food Res
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
García-Ruano C, Costa A, Palou A, Oliver P.   +3 more
europepmc   +2 more sources

Sex-Specific Lasting Metabolome Effects of Adverse Gestational Conditions and Prevention by Myo-Inositol Supplementation During Suckling. [PDF]

Mol Nutr Food Res
This graphical abstract illustrates the effects of myo‐inositol supplementation during suckling in reducing long‐term metabolic impacts from mild gestational calorie restriction (GCR). Using a metabolomics approach, 164 metabolites were identified, with greater metabolic alterations in males.
Martín-Chamorro RA, Martin JC, Castillo P, Palou M, Palou A, Rodríguez AM, Picó C.   +6 more
europepmc   +2 more sources

Biochemical Composition and Related Potential Nutritional and Health Properties of Sobrassada de Mallorca [PDF]

Foods
‘Sobrassada de Mallorca’ is an EU PGI (Protected Geographical Indication) -qualified traditional food with important historical, social, and gastronomical relevance. However, its nutritional features are poorly characterized.
Sebastià Galmés, Bàrbara Reynés, Alicia Domínguez-Flores, Silvia Terradas, Antonia María Torres, Andreu Palou   +5 more
doaj   +2 more sources

TLCD4 as Potential Transcriptomic Biomarker of Cold Exposure [PDF]

Biomolecules
(1) Background: Cold exposure induces metabolic adaptations that can promote health benefits, including increased energy disposal due to lipid mobilization in adipose tissue (AT).
Bàrbara Reynés, Estefanía García-Ruiz, Evert M. van Schothorst, Jaap Keijer, Paula Oliver, Andreu Palou   +5 more
doaj   +2 more sources

Maternal choline supplementation mitigates premature foetal weight gain induced by an obesogenic diet, potentially linked to increased amniotic fluid leptin levels in rats [PDF]

Scientific Reports
Placental leptin may impact foetal development. Maternal overnutrition has been linked to increased plasma leptin levels and adverse effects on offspring, whereas choline, an essential nutrient for foetal development, has shown promise in mitigating some
Zhi Xin Yau-Qiu, Sebastià Galmés, Pedro Castillo, Catalina Picó, Andreu Palou, Ana María Rodríguez   +5 more
doaj   +2 more sources

Impact of Western diet on milk miRNAs and target genes in offspring adipose tissue: modulation by betaine during suckling. [PDF]

Obesity (Silver Spring)
Abstract Objective We investigated how a maternal Western diet (WD) affects milk microRNA (miRNA) profile and associates with metabolic programming in adipose tissues in pups. We also explored the impact of betaine supplementation during suckling, as betaine levels are reported to be reduced in WD‐fed dams' milk.
Martín-Chamorro RA, Pomar CA, Palou A, Picó C, Rodríguez AM.   +4 more
europepmc   +2 more sources

Interpreting the Extremely Diffuse Stellar Distribution of the Nube Galaxy through Fuzzy Dark Matter

Astrophysical Journal Letters
Recent observations have uncovered a remarkably flat and extremely diffuse stellar distribution within the almost dark dwarf galaxy Nube, posing a challenge to the standard cold dark matter scenario.
Yu-Ming Yang, Zhao-Chen Zhang, Xiao-Jun Bi, Peng-Fei Yin   +3 more
exaly   +2 more sources

Fallos de las imágenes spam en la era de la hiperconexión

Hart, 2021
El presente texto aborda la importancia que tiene la imagen digital conectada en determinados ámbitos de nuestra vida cotidiana en una sociedad hiperconectada.
Geraldiny Guerrero Muñoz
doaj   +1 more source

Modelo de integración TIC en la nube a la gestión administrativa en las pymes del sector educativo

Revista Científica Ciencia y Tecnología, 2022
Reducir costos es la motivación principal que tienen las pymes para cambiar de un sistema informático tradicional a un entorno en la nube, sin embargo, no cuentan con la cantidad suficiente de recursos tecnológicos de TI basados en la nube computacional ...
José Townsend Valencia, Douglas Ayala Bravo   +1 more
doaj   +1 more source