Metabolomic Insights Into the Impact of a Maternal Western-Style Diet and Leptin Supplementation During Suckling on Adult Rat Offspring. [PDF]
Plasma metabolites in adult offspring reflecting metabolic programming during critical developmental windows. ABSTRACT Perinatal nutrition influences offspring metabolic phenotype and obesity risk. This study examines how a maternal obesogenic diet and offspring's leptin supplementation during suckling affect the metabolome in offspring adulthood ...
Pomar CA +8 more
europepmc +2 more sources
Altered Hippocampal Transcriptomic Profile Reveals Cognitive Impairment in Young Metabolically Obese, Normal-Weight Rats, Prevented by Perinatal Leptin Intake. [PDF]
Early‐life exposure of rats to high‐fat‐isocaloric diet leads to metabolically obese, normal‐weight phenotype, and impaired cognition. Hippocampal transcriptomic analysis reveals disruption in pathways linked to obesity and cognitive decline, which is mitigated by perinatal leptin supplementation. PBMC share common altered genes with hippocampus, which
García-Ruano C +3 more
europepmc +2 more sources
Sex-Specific Lasting Metabolome Effects of Adverse Gestational Conditions and Prevention by Myo-Inositol Supplementation During Suckling. [PDF]
This graphical abstract illustrates the effects of myo‐inositol supplementation during suckling in reducing long‐term metabolic impacts from mild gestational calorie restriction (GCR). Using a metabolomics approach, 164 metabolites were identified, with greater metabolic alterations in males.
Martín-Chamorro RA +6 more
europepmc +2 more sources
Impact of Western diet on milk miRNAs and target genes in offspring adipose tissue: modulation by betaine during suckling. [PDF]
Abstract Objective We investigated how a maternal Western diet (WD) affects milk microRNA (miRNA) profile and associates with metabolic programming in adipose tissues in pups. We also explored the impact of betaine supplementation during suckling, as betaine levels are reported to be reduced in WD‐fed dams' milk.
Martín-Chamorro RA +4 more
europepmc +2 more sources
Abstract Since 2019, researchers examining, archiving, and collecting extremist and terrorist materials online have increasingly been taken offline. In part a consequence of the automation of content moderation by different technology companies and national governments calling for ever quicker takedowns. Based on an online survey of peers in the field,
Aaron Y. Zelin
wiley +1 more source
Port Authority of Cartagena: Evidence of a Sustainability Balanced Scorecard
Abstract This paper provides a deeper understanding to the development and implementation of a Sustainability Balanced Scorecard in the Port Authority of Cartagena, under exploratory research. Open‐access documents available on different websites were used as data sources combined with semi‐structured personal interviews, which took place at the ...
Carlos Suárez‐Gargallo +1 more
wiley +1 more source
Reverting to a healthy maternal diet during lactation normalizes the altered milk metabolome found in obese rats. Stachydrine, N‐acetylornithine and TMAO levels are proposed as candidate biomarkers of maternal consumption of an obesogenic diet during lactation.
Pedro Castillo +6 more
wiley +1 more source
We analyzed floral traits and pollinator assemblages in the Neotropical species Costus guanaiensis var. tarmicus along a steep elevational gradient in Peru. Results show floral traits and pollinator assemblage variation along the elevational gradient. We examined our results considering two hypotheses: (1) local adaptation to different bee assemblages ...
Rossana Maguiña‐Conde +2 more
wiley +1 more source
Principales riesgos de seguridad en computación móvil en la nube: una revisión de la literatura
La computación móvil en la nube está expandiéndose entre los usuarios de dispositivos móvil, brindando una plataforma para sus servicios dentro de estos dispositivos.
Alberto Carlos Mendoza De Los Santos +2 more
doaj +1 more source
Introduction to the Third Issue
Presentazione del terzo numero di «NuBE».Introduction to the Third Issue of «NuBE»
Redazione NuBE
core +1 more source

