Results 31 to 40 of about 29,041 (298)

Metastatic niche shaped by host factors influences disseminated cancer cell fate

FEBS Letters, EarlyView.
Metastasis is shaped not only by cancer cells but also by the environments they encounter. This review explores how factors such as aging, diet, the microbiome, lifestyle, and environmental exposures remodel organ‐specific niches in the lung, liver, bone, and brain, influencing where metastatic cells survive, remain dormant, or grow, and ultimately ...
Gwennan Delyth Ward, Álvaro Ruiz‐Tabas, Patricia Altea‐Manzano   +2 more
wiley   +1 more source

(Nuclear theory). [Research in nuclear physics]

, 1990
This report discusses research in nuclear physics. Topics covered in this paper are: symmetry principles; nuclear astrophysics; nuclear structure; quark-gluon plasma; quantum chromodynamics; symmetry breaking; nuclear deformation; and cold fusion ...
Haxton, W.
core   +1 more source

Experimental Validation of a Naphthalene-Fueled Electrothermal Plasma Thruster

IEEE Access
A direct thrust measurement of an electrothermal radio-frequency (RF) plasma thruster, also known as a Pocket-Rocket, using naphthalene as a propellant, is experimentally performed.
Thimthana Lee, Mahdi Davoodianidalik, Dimitrios Tsifakis, Roderick W. Boswell, Christine Charles   +4 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

Molecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka, Wioleta Cieślik, Wojciech Płaziński, Katarzyna Stępnik, Anna Boguszewska‐Czubara, Elżbieta Kot, Robert Musioł, Mateusz Jasica, Anna Mrozek‐Wilczkiewicz, Katarzyna Malarz   +9 more
wiley   +1 more source

Insights into type-I edge localized modes and edge localized mode control from JOREK non-linear magneto-hydrodynamic simulations

, 2018
Edge localized modes (ELMs) are repetitive instabilities driven by the large pressure gradients and current densities in the edge of H-mode plasmas. Type-I ELMs lead to a fast collapse of the H-mode pedestal within several hundred microseconds to a few ...
Pamela, S., Huijsmans, G., Trier, E, Huijsmans, G. T. A.,, Guenter, S, EUROfusion MST1 Team, F. Liu, Krebs, I.,, Orain, F, Vanovac, B, Orain, F., Frassinetti, L, Bécoulet, M, Trier, E.,, Dunne, M., Mink, F, Artola, F J, Futatani, S., Krebs, I, Pamela, S.,, G.T.A. Huijsmans, A. Lessig, Orain, F.,, Lackner, K., Artola, F.J., K. Lackner, Lessig, A, Guenter, S.,, Liu, F., Artola, F. J., S. Guenter, Huijsmans, GTA Guido, Trier, E., Huijsmans, G.T.A., Eich, T., F. Mink, Artola, F., Viezzer, E, I. Krebs, Vanovac, B., Hoelzl, M., null null, Wolfrum, E.,, Pamela, S, Futatani, S.,, Wolfrum, E., Hoelzl, M.,, T. Eich, E. Viezzer, Vanovac, B.,, Mink, F., Krebs, I., Huijsmans, G. T. A., Frassinetti, L., M. Hoelzl, Artola, F. J.,, Vugt, DC Daan van, E. Wolfrum, Mink, F.,, Eich, T, Dunne, M.,, Becoulet, M.,, Hölzl, M., Lessig, A., Lackner, K.,, S. Pamela, B. Vanovac, Lackner, K, van Vugt, D.,, M. Dunne, Gunter, S., E. Trier, Futatani, S, Eich, T.,, L. Frassinetti, Lessig, A.,, Frassinetti, Lorenzo,, Viezzer, E.,, Bécoulet, M., ASDEX Upgrade Team, F. Orain, Vugt, D., Hoelzl, M, Liu, F.,, Viezzer, E., Liu, F, D. van Vugt, van Vugt, D., S. Futatani, M. Becoulet, F.J. Artola, Wolfrum, E, Guenter, S., Dunne, M   +93 more
core   +1 more source

Alternative solid hydrocarbons as propellants for electrothermal plasma radio-frequency thrusters

Scientific Reports
Onboard propulsion is vital for extending the operational lifespan of CubeSat missions. Although electrothermal plasma thrusters are a promising low-power solution, their development has historically focused on gaseous propellants, leaving alternative ...
Thimthana Lee, Mahdi Davoodianidalik, Dimitrios Tsifakis, Roderick W Boswell, Christine Charles   +4 more
doaj   +1 more source

Somatostatin receptor 4 (SSTR4) is a tumor suppressor in cutaneous and head & neck squamous cell carcinomas

Molecular Oncology, EarlyView.
This study identifies somatostatin receptor 4 (Sstr4) as a critical tumor suppressor against skin and head/neck cancers (HNSCC, cSCC, and BCC). The loss of Sstr4 removes a check on cell growth, causing hyperactivation of the MAPK‐ERK signaling pathway (↑).
Ali Taqvi, Tuan Khang Huynh, Adway Kadam, Zahra Kardan, Yue Yan, Amina Jamal Laham, Sampath Kumar Loganathan   +6 more
wiley   +1 more source

Ion stopping in dense plasma target for high energy density physics [PDF]

, 2010
The basic physics of nonrelativistic and electromagnetic ion stopping in hot and ionized plasma targets is thoroughly updated. Corresponding projectile-target interactions involve enhanced projectile ionization and coupling with target free electrons ...
Hasegawa, Jun, Sharkov, Boris Y., Deutsch, Claude, Chabot, Marin, Golubev, Alexey A., Ogawa, Masao, Bimbot, René, Jacoby, Joachim, Couillaud, Christophe, Mintsev, Victor, Della-Negra, Serge, Hoffmann, Dieter H. H., Wahl, H., Weyrich, Karin, Gardes, Daniel, Fleurier, Claude, Fertman, Alexander, Maynard, Gilles, Rivet, Marie-France, Tahir, Naeem Ahmad, Rosmej, Olga N., Fortov, Vladimir E., Oguri, Yoshiyuki   +22 more
core  

Investigation of the effect of target density profile in proton laser acceleration [PDF]

مجله علوم و فنون هسته‌ای
The common mechanism of proton laser acceleration is Target Normal Sheath acceleration. This study investigates the geometry of the aluminum target used in high-intensity laser pulse interaction with plasma.
A. Hasan Beigi, F. Azizian, M.J. Jafari, S. Rezaei   +3 more
doaj   +1 more source

Arginine methylation as a regulatory ratchet in cancer: From substrate selection to malignant‐state stabilization

Molecular Oncology, EarlyView.
Arginine methylation can be viewed as a persistence‐prone post‐translational modification regulated by a network of PRMTs. Competitive and compensatory interactions among PRMTs can redistribute methylation across substrate pools shaped by sequence, structural, spatial, and environmental layers, reinforcing RNA‐processing, chromatin, and signaling ...
So Hyun Kwon, Ji Min Lee
wiley   +1 more source