Results 201 to 210 of about 13,358 (220)
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2017
Herpesviruses assemble and package their genomes into capsids in the nucleus, but complete final assembly of the mature virion in the cell cytoplasm. This requires passage of the genome-containing capsid across the double-membrane nuclear envelope. Herpesviruses have evolved a mechanism that relies on a pair of conserved viral gene products to shuttle ...
Richard J, Roller, Joel D, Baines
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Herpesviruses assemble and package their genomes into capsids in the nucleus, but complete final assembly of the mature virion in the cell cytoplasm. This requires passage of the genome-containing capsid across the double-membrane nuclear envelope. Herpesviruses have evolved a mechanism that relies on a pair of conserved viral gene products to shuttle ...
Richard J, Roller, Joel D, Baines
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Computational Egress Simulation and Analysis for Nuclear Reactor Building
Proceedings of the 2nd International Conference on Computer Science and Application Engineering, 2018In1 order to increase the fire safely level of nuclear power plant reactor building, occupant evacuation for reactor building during the maintenance period is investigated. The staff characteristics and site egress conditions for a reactor building during maintenance period are analyzed. The total occupant evacuation for various credible fire scenarios
Feng Xue +4 more
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Nuclear egress of herpesviruses
Virologica Sinica, 2008Herpesviruses assemble and fill their capsids in the infected cell nucleus, and must then move this enormous macromolecular assembly across the nuclear membrane and into the cytoplasm. Doing so is a complex, multi-step process that involves envelopment of the capsid at the inner nuclear membrane and de-envelopment by fusion with the outer nuclear ...
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Electron microscopic characterization of nuclear egress in the sea urchin gastrula
Journal of Morphology, 2018AbstractNuclear egress, also referred to as nuclear envelope (NE) budding, is a process of transport in which vesicles containing molecular complexes or viral particles leave the nucleus through budding from the inner nuclear membrane (INM) to enter the perinuclear space. Following this event, the perinuclear vesicles (PNVs) fuse with the outer nuclear
Nicole LaMassa +2 more
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Analysis of the nuclear egress complex of mouse cytomegalovirus
2007Herpesvirus infections are usually asymptomatic or associated with mild symptoms. Fatal diseases are seen in immune suppressed and immune incompetent individuals. Although herpesviruses are of emerging medical importance nowadays an infection only can be controlled by chemotherapeutics, which target viral DNA replication and cause negative side effects.
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Reconstitution of the herpesviral pUL31-pUL34 nuclear egress complex function
2015Um sich in einer Vielzahl von Wirten vermehren zu können, haben sich Herpesviren im Laufe ihrer Evolution erfolgreich angepasst. Sie sind die bisher einzig bekannten Viren, die nach einer Erstinfektion ein Leben lang in ihrem Wirtsorganismus persistieren, indem sie in eine Art Ruhezustand (Latenz) übergehen.
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Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport.
Advances in virus research, 2016Herpesvirus particles mature in two different cellular compartments. While capsid assembly and packaging of the genomic linear double-stranded DNA occur in the nucleus, virion formation takes place in the cytoplasm by the addition of numerous tegument proteins as well as acquisition of the viral envelope by budding into cellular vesicles derived from ...
Teresa, Hellberg +4 more
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