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Hsp90 inhibitor AT-533 blocks HSV-1 nuclear egress and assembly
The Journal of Biochemistry, 2018Heat shock protein 90 (Hsp90) has been identified as an essential host factor for the infection and replication of several viruses, including HSV-1. Recent works have clearly shown that Hsp90 plays a role in the early stages of HSV-1 infection, including nuclear import and DNA replication.
Feng, Li +9 more
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Electron microscopic characterization of nuclear egress in the sea urchin gastrula
Journal of Morphology, 2018AbstractNuclear egress, also referred to as nuclear envelope (NE) budding, is a process of transport in which vesicles containing molecular complexes or viral particles leave the nucleus through budding from the inner nuclear membrane (INM) to enter the perinuclear space. Following this event, the perinuclear vesicles (PNVs) fuse with the outer nuclear
Nicole LaMassa +2 more
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Nuclear Egress of Herpesviruses: The Prototypic Vesicular Nucleocytoplasmic Transport.
Advances in virus research, 2016Herpesvirus particles mature in two different cellular compartments. While capsid assembly and packaging of the genomic linear double-stranded DNA occur in the nucleus, virion formation takes place in the cytoplasm by the addition of numerous tegument proteins as well as acquisition of the viral envelope by budding into cellular vesicles derived from ...
Teresa, Hellberg +4 more
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β-Coronaviruses Use Lysosomes for Egress Instead of the Biosynthetic Secretory Pathway
Cell, 2020Sourish Ghosh +2 more
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Molecular imaging in oncology: Current impact and future directions
Ca-A Cancer Journal for Clinicians, 2022Steven P Rowe, Martin G Pomper
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Herpesviruses remodel host membranes for virus egress
Nature Reviews Microbiology, 2011David Johnson, Joel D Baines
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Structural basis of membrane budding by the nuclear egress complex of herpesviruses
EMBO Journal, 2015Ekaterina E Heldwein
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Unexpected features and mechanism of heterodimer formation of a herpesvirus nuclear egress complex
EMBO Journal, 2015Kamel El Omari +2 more
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