Results 91 to 100 of about 1,198,165 (223)

Ubiquitination of transcription factors in cancer: unveiling therapeutic potential

Molecular Oncology, EarlyView.
In cancer, dysregulated ubiquitination of transcription factors contributes to the uncontrolled growth and survival characteristics of tumors. Tumor suppressors are degraded by aberrant ubiquitination, or oncogenic transcription factors gain stability through ubiquitination, thereby promoting tumorigenesis.
Dongha Kim, Hye Jin Nam, Sung Hee Baek
wiley   +1 more source

Can nuclear energy contribute to the energy transition? [PDF]

In the course of the energy transition, energy generation from nuclear power - through nuclear fission and perhaps in the future through nuclear fusion - is often proposed as an alternative or supplement to renewable energy sources. There are already good reasons why electricity generation from nuclear energy is significantly more expensive than other ...
arxiv   +1 more source

Harnessing Nuclear Energy to Gold Nanoparticles for the Concurrent Chemoradiotherapy of Glioblastoma. [PDF]

Nanomaterials (Basel), 2023
Li JP, Kuo YC, Liao WN, Yang YT, Chen SY, Chien YT, Wu KH, Wang MY, Chou FI, Yang MH, Hueng DY, Yang CS, Chen JK.   +12 more
europepmc   +1 more source

Determination of ADP/ATP translocase isoform ratios in malignancy and cellular senescence

Molecular Oncology, EarlyView.
The individual functions of three isoforms exchanging ADP and ATP (ADP/ATP translocases; ANTs) on the mitochondrial membrane remain unclear. We developed a method for quantitatively differentiating highly similar human ANT1, ANT2, and ANT3 using parallel reaction monitoring. This method allowed us to assess changes in translocase levels during cellular
Zuzana Liblova, Dominika Maurencova, Barbora Salovska, Marek Kratky, Tomas Mracek, Zuzana Korandova, Alena Pecinova, Pavla Vasicova, David Rysanek, Ladislav Andera, Ivo Fabrik, Rudolf Kupcik, Pavel Kashmel, Pinky Sultana, Vojtech Tambor, Jiri Bartek, Josef Novak, Marie Vajrychova, Zdenek Hodny   +18 more
wiley   +1 more source

Measurement and calculation of neutron leakage spectra from slab samples of beryllium, gallium and tungsten irradiated with 14.8 MeV neutrons

EPJ Web of Conferences, 2017
In order to make benchmark validation of the nuclear data for gallium (Ga), tungsten (W) and beryllium (Be) in existing modern evaluated nuclear data files, neutron leakage spectra in the range from 0.8 to 15 MeV from slab samples were measured by time ...
Nie Y.B., Ruan X.C., Ren J., Zhang S., Han R., Bao J., Huang H.X., Ding Y.Y., Wu H.C., Liu P., Zhou Z.Y.   +10 more
doaj   +1 more source

Understanding and measuring mechanical signals in the tumor stroma

FEBS Open Bio, EarlyView.
This review discusses cancer‐associated fibroblast subtypes and their functions, particularly in relation to extracellular matrix production, as well as the development of 3D models to study tumor stroma mechanics in vitro. Several quantitative techniques to measure tissue mechanical properties are also described, to emphasize the diagnostic and ...
Fàtima de la Jara Ortiz, Chiara Cimmino, Maurizio Ventre, Alessandra Cambi   +3 more
wiley   +1 more source

Supramolecular polynuclear clusters sustained cubic hydrogen bonded frameworks with octahedral cages for reversible photochromism

Nature Communications
Developing supramolecular porous crystalline frameworks with tailor-made architectures from advanced secondary building units (SBUs) remains a pivotal challenge in reticular chemistry.
Xiaojun Ding, Jing Chen, Gang Ye
doaj   +1 more source

Evaluation of synaptotagmin‐1 action models by all‐atom molecular dynamics simulations

FEBS Open Bio, EarlyView.
We used molecular dynamics simulations to test models proposing that synaptotagmin‐1 facilitates membrane fusion by perturbing lipid bilayers, inducing membrane curvature and/or bridging membranes. The simulations show that synaptotagmin‐1 C2‐domains placed near the site of fusion hinder the ability of SNARE complexes to bring the membranes together ...
Josep Rizo, Klaudia Jaczynska, Christian Rosenmund   +2 more
wiley   +1 more source

Stochastic Jet Quenching in High Energy Nuclear Collisions [PDF]

arXiv, 2008
Energy losses of fast color particles in random inhomogeneous color medium created in high energy nuclear collisions are estimated.
arxiv  

Role of natural gas and nuclear energy consumption in fostering environmental sustainability in India. [PDF]

Sci Rep, 2023
Adebayo TS, Ozturk I, Ağa M, Uhunamure SE, Kirikkaleli D, Shale K.   +5 more
europepmc   +1 more source