Results 31 to 40 of about 27,307 (225)

The CIELO collaboration: Progress in international evaluations of neutron reactions on Oxygen, Iron, Uranium and Plutonium

EPJ Web of Conferences, 2017
The CIELO collaboration has studied neutron cross sections on nuclides that significantly impact criticality in nuclear technologies – 16O, 56Fe, 235,8U and 239Pu – with the aim of improving the accuracy of the data and resolving previous discrepancies ...
Chadwick M.B., Capote R., Trkov A., Kahler A.C., Herman M.W., Brown D.A., Hale G.M., Pigni M., Dunn M., Leal L., Plompen A., Schillebeeck P., Hambsch F.-J., Kawano T., Talou P., Jandel M., Mosby S., Lestone J., Neudecker D., Rising M., Paris M., Nobre G.P.A., Arcilla R., Kopecky S., Giorginis G., Cabellos O., Hill I., Dupont E., Danon Y., Jing Q., Zhigang G., Tingjin L., Hanlin L., Xichao R., Haicheng W., Sin M., Bauge E., Romain P., Morillon B., Noguere G., Jacqmin R., Bouland O., De Saint Jean C., Pronyaev V.G., Ignatyuk A., Yokoyama K., Ishikawa M., Fukahori T., Iwamoto N., Iwamoto O., Kuneada S., Lubitz C.R., Palmiotti G., Salvatores M., Kodeli I., Kiedrowski B., Roubtsov D., Thompson I., Quaglioni S., Kim H.I., Lee Y.O., Koning A.J., Carlson A., Fischer U., Sirakov I.   +64 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

FEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee, Dimitrios Bekiari, Sofia Doello, Karl Forchhammer   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

FEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Research on Lightweight Technology of Hydraulic Components for Integrated Fast Reactor Main Pump

Yuanzineng kexue jishu
To meet the requirements of our country’s nuclear energy development and defense technology industry development, and to achieve national carbon neutrality and energy security needs, it is necessary to comprehensively break through and master the key ...
PU Enshan1, ZHAI Xiao1, GU Jipin1, LIU Simin1, ZHANG Xu2
doaj   +1 more source

Optimization Research of Neutron Flux Density Monitoring Method during Refueling for Tianwan NPP

Yuanzineng kexue jishu, 2023
The ex-core nuclear instrument equipment consists of the source range detector, the start-up and work range detector and the refueling monitoring range detector in Tianwan nuclear power plant (NPP). The neutron flux density of the reactor is monitored by
LYU Niu;LI Dongpeng;XIA Zhaodong;WANG Yang
doaj  

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Resonance region measurements of dysprosium and rhenium

EPJ Web of Conferences, 2017
Neutron capture and transmission measurements have been performed, and resonance parameter analysis has been completed for dysprosium, Dy, and rhenium, Re. The 60 MeV electron accelerator at RPI Gaerttner LINAC Center produced neutrons in the thermal and
Leinweber Gregory, Block Robert C., Epping Brian E., Barry Devin P., Rapp Michael J., Danon Yaron, Donovan Timothy J., Landsberger Sheldon, Burke John A., Bishop Mary C., Youmans Amanda, Kim Guinyun N., Kang yeong-rok, Lee Man Woo, Drindak Noel J.   +14 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source