Results 51 to 60 of about 28,546 (217)

Research on Novel Startup and Restart Process of Cold Crucible Melter

open access: yesYuanzineng kexue jishu
Cold crucible melter (CCM) technology holds broad application prospects in radioactive waste treatment due to its advantages of long equipment service life, wide adaptability to waste types, and high safety.
ZHANG Keqian1, QIE Dongsheng1, HE Cheng1, LONG Haoqi1, TAN Shengheng1, , LI Zhongdi2, , DONG Hailong2, RUAN Minyi2
doaj   +1 more source

Numerical Analysis of Turbulent Mixed Convection in Vertical Annular Channel

open access: yesYuanzineng kexue jishu, 2023
Reactor cavity cooling system (RCCS) is a competitive residual heat removal scheme for small modular reactors. In this paper, the RCCS has been simplified to a scenario that ascending air flow is got heated in vertical annular channels and driven by ...
HU Xiangjie;WEN Jiming;GAO Puzhen;TIAN Ruifeng
doaj  

Accurate and noninvasive prostate cancer detection using plasma‐derived extracellular vesicle RNA

open access: yesFEBS Open Bio, EarlyView.
Plasma extracellular vesicles were captured with WGA‐conjugated magnetic beads and profiled for RNA biomarkers. A three‐RNA panel (NM_024955, NR_047469, and NR_002564) distinguished prostate cancer from healthy controls and benign prostatic hyperplasia, supporting a simple, noninvasive approach to improve prostate cancer detection.
Hanping Wei, Haoran Wu, Wei Feng
wiley   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Reinforcement Learning-Based Augmentation of Data Collection for Bayesian Optimization Towards Radiation Survey and Source Localization

open access: yesJournal of Nuclear Engineering
Safer and more efficient characterization of radioactive environments requires exploring intelligently, utilizing robotic systems which use smart strategies and physics-based statistical models.
Jeremy Marquardt   +2 more
doaj   +1 more source

Sustainable progression of technology education for atomic energy engineering in tsuyama national college of technology

open access: yesMechanical Engineering Journal, 2014
This study describes the achievements of a program that provides technology education about radiation to develop practical core engineers, then the effects of the programed were discussed.
Toshiro KOBAYASHI   +7 more
doaj   +1 more source

Chronobiology of Cancer: How Aging Fuels Oncogenesis at the Molecular Level

open access: yesAging and Cancer, EarlyView.
This graphical abstract illustrates the key biological pathways linking aging with cancer development and progression. In the upper left, cumulative exposure to ultraviolet radiation, toxins, and reactive oxygen species (ROS) causes DNA damage and genomic instability, whereas age‐related decline in repair mechanisms, such as ATM/ATR, BER, and NER ...
Anu Singh, Aroonima Misra, Sufian Zaheer
wiley   +1 more source

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu   +21 more
wiley   +1 more source

Neurochemical Endpoints to Inform Early‐Stage Trials of Spinocerebellar Ataxia 2 and 3 in a Multisite Setting

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Neurochemical levels measured by brain MR spectroscopy (MRS) have been proposed as endpoints for clinical trials in early‐stage spinocerebellar ataxia (SCA) trials. We tested their trial‐readiness by quantifying neurochemicals in three affected brain regions in early‐stage cohorts of SCA2 and SCA3, examining their reproducibility in ...
James M. Joers   +19 more
wiley   +1 more source

Rheumatoid Arthritis and Coronary Artery Calcium Progression: A Case Cohort Analysis From ELSA‐Brasil

open access: yesArthritis Care &Research, EarlyView.
Objective To investigate the association between rheumatoid arthritis (RA) and coronary artery calcium (CAC) prevalence, incidence, and progression over four years in adults without prior cardiovascular disease. Methods A case‐cohort study within the Brazilian Longitudinal Study of Adult Health (ELSA‐Brasil) included 585 participants (86 patients with ...
Patrícia Fonseca Estrada   +7 more
wiley   +1 more source

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