Results 51 to 60 of about 10,707,057 (260)

Performance Test of High-temperature Immersion Pump for In-reactor Purification of Integrated Fast Reactor

open access: yesYuanzineng kexue jishu
In the integrated fast reactor project of the China Institute of Atomic Energy, in order to keep the primary circuit sodium within the reactor and prevent radioactive sodium leakage, an in-reactor cold trap is used to purify the impurities in the sodium,
LI Xu1, GENG Xiao1, YAO Zewen1, , YU Chunli1, WU Peng2, YU Genfang2
doaj   +1 more source

Resonance region measurements of dysprosium and rhenium

open access: yesEPJ Web of Conferences, 2017
Neutron capture and transmission measurements have been performed, and resonance parameter analysis has been completed for dysprosium, Dy, and rhenium, Re. The 60 MeV electron accelerator at RPI Gaerttner LINAC Center produced neutrons in the thermal and
Leinweber Gregory   +14 more
doaj   +1 more source

A novel quinazolinone insulin receptor inhibitor and its synergy with an EGFR inhibitor in glucose‐driven glioblastoma

open access: yesMolecular Oncology, EarlyView.
The novel styrylquinazolinone‐based molecule W1B effectively suppresses glioblastoma by inhibiting IGF1R and EGFR. In high‐glucose microenvironments driving tumor resistance, W1B acts synergistically with the EGFR inhibitor dacomitinib. This combination safely blocks compensatory survival signaling in zebrafish xenograft models. Showcasing promising in
Patryk Rurka   +9 more
wiley   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

open access: yesMolecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

open access: yesMolecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho   +2 more
wiley   +1 more source

Refinement of amino‐acid conformation vs. difference density maps in time‐resolved serial femtosecond crystallography data analysis

open access: yesFEBS Open Bio, EarlyView.
The dFoCC pipeline starts with observed DED and resting‐state coordinates, which are then used to generate a library of triggered states. Correlation analysis of the calculated DED features of each candidate vs observed DED permits quantitative evaluation of candidate structural quality.
Meng Iao Fong   +3 more
wiley   +1 more source

APDA Bulletin 123

open access: yes, 1957
Progress report issued by the APDA over research and development activities of the Enrico Fermi Atomic Power Plant.
Atomic Power Development Associates
core  

Landscape, environment and community impacts of nuclear power [PDF]

open access: yes, 2012
This paper is the third in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.This document investigates the landscape impacts of all the processes involved in nuclear power from mining the ...
Sustainable Development Commission
core   +2 more sources

Eugene P. Wigner’s Visionary Contributions to Generations-I through IV Fission Reactors

open access: yesEPJ Web of Conferences, 2014
Among Europe’s greatest scientists who fled to Britain and America in the 1930s, Eugene P. Wigner made instrumental advances in reactor physics, reactor design and technology, and spent nuclear fuel processing for both purposes of developing atomic ...
Carré Frank
doaj   +1 more source

UiO‐66 metal–organic frameworks in biomedicine: From structural tunability to bioimaging, photodiagnostics, and photodynamic cancer therapy

open access: yesFEBS Open Bio, EarlyView.
UiO‐66(Zr) metal–organic frameworks are chemically stable, biocompatible, and highly tunable nanomaterials. Their modular structure enables controlled drug delivery, multimodal bioimaging, and light‐activated photodynamic therapy, supporting integrated diagnostic and therapeutic (theranostic) applications in cancer and biomedical research.
Veronika Huntošová   +2 more
wiley   +1 more source

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