Results 71 to 80 of about 195,424 (265)

MiR‐513a promotes human erythroid differentiation by modulating c‐Jun

FEBS Open Bio, EarlyView.
During early human erythropoiesis, miR‐513a promoted erythroid differentiation in primary human CD34+ hematopoietic stem‐progenitor cells and human TF‐1 erythroleukemic cells by indirectly decreasing c‐Jun and phospho‐c‐Jun expression, which are associated with increased GATA1 expression.
MinJung Kim, Brittany Taylor, Shannon Bolten, Christian L. Eberly, Mahliya Abdurahman, T. Michael Creed, Acong Yang, Taylor L. Hatchet, Tristan Dyson, Shuo Gu, Curt I. Civin, Tami J. Kingsbury   +11 more
wiley   +1 more source

TAMING THE TECHNOLOGICAL TYGERTHE REGULATION OF THE ENVIRONMENTAL EFFECTS OF NUCLEAR POWER PLANTS -A SURVEY OF SOME CONTROVERSIAL ISSUES--PART TWO [PDF]

, 1972
This article reviews the significance placed on environmental factors in nuclear plant licensing during -the 1960s, first considering the effect of recent legislation and the status of current controversies, and then briefly discussing proposals for ...
Davis, Joyce P.
core   +1 more source

Large‐scale bidirectional arrayed genetic screens identify OXR1 and EMC4 as modifiers of αSynuclein aggregation

FEBS Open Bio, EarlyView.
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane, Lea Nikolić, Lorenzo Maraio, Thomas Goiran, Nathan Karpilovsky, Stefano Sellitto, Vangelis Bouris, Jiang‐An Yin, Ronald Melki, Edward A Fon, Adriano Aguzzi, Elena De Cecco   +11 more
wiley   +1 more source

Reinforcement Learning-Based Augmentation of Data Collection for Bayesian Optimization Towards Radiation Survey and Source Localization

Journal of Nuclear Engineering
Safer and more efficient characterization of radioactive environments requires exploring intelligently, utilizing robotic systems which use smart strategies and physics-based statistical models.
Jeremy Marquardt, Leonard Lucas, Stylianos Chatzidakis   +2 more
doaj   +1 more source

Sustainable progression of technology education for atomic energy engineering in tsuyama national college of technology

Mechanical Engineering Journal, 2014
This study describes the achievements of a program that provides technology education about radiation to develop practical core engineers, then the effects of the programed were discussed.
Toshiro KOBAYASHI, Manabu KATO, Hitoshi SORI, Yuji SASAI, Makoto SATO, Tomomi INADA, Kanji HARADA, Tadashi OKADA   +7 more
doaj   +1 more source

Fluid Biomarkers of Disease Burden and Cognitive Dysfunction in Progressive Supranuclear Palsy

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Identifying objective biomarkers for progressive supranuclear palsy (PSP) is crucial to improving diagnosis and establishing clinical trial and treatment endpoints. This study evaluated fluid biomarkers in PSP versus controls and their associations with regional 18F‐PI‐2620 tau‐PET, clinical, and cognitive outcomes.
Roxane Dilcher, Charles B. Malpas, Stuart J. McDonald, William T. O’Brien, Craig Despott, Kelly L. Bertram, Matthew P. Pase, Lukas Frontzkowski, Meng Law, Terence J. O’Brien, Lucy Vivash   +10 more
wiley   +1 more source

Tailoring quantum superpositions with linearly polarized amplitude-modulated light

, 2010
Amplitude-modulated nonlinear magneto-optical rotation is a powerful technique that offers a possibility of controllable generation of given quantum states.
Cincio, L., Gawlik, W., Koczwara, M., Pustelny, S.   +3 more
core   +1 more source

Impact of nuclear vibrations on van der Waals and Casimir interactions at zero and finite temperature [PDF]

, 2018
Van der Waals (vdW) and Casimir interactions depend crucially on material properties and geometry, especially at molecular scales, and temperature can produce noticeable relative shifts in interaction characteristics.
Hermann, Jan, Rodriguez, Alejandro W., Tkatchenko, Alexandre, Venkataram, Prashanth S., Vongkovit, Teerit J.   +4 more
core   +2 more sources

RNA Sequencing Resolves Cryptic Pathogenic Variants in Mitochondrial Disease

Annals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Mitochondrial diseases are the most common inherited metabolic disorders, characterized by pronounced clinical and genetic heterogeneity that complicates molecular diagnosis. Although DNA‐based sequencing approaches have become standard in genetic testing, up to half of patients remain without a definitive diagnosis.
Zhimei Liu, Xin Duan, Fatemeh Peymani, Jia Wang, Chengjia Bao, Chaolong Xu, Ying Zou, Zixuan Zhang, Yunxi Zhang, Tongyue Li, Martin Pavlov, Junling Wang, Minhan Song, Tianyu Song, Xiaodi Han, Mingxi Sun, Danmin Shen, Ruoyu Duan, Huafang Jiang, Manting Xu, Holger Prokisch, Fang Fang   +21 more
wiley   +1 more source

The Changing Role of the Atomic Energy Commission in Atomic Power Development [PDF]

, 1956
Samhällets finansiering av bostadsbyggandet har minskat radikalt. Nyproducerade bostäder erbjuds främst till kundgrupper med kapital. Därför är det viktigt att se på bostadsefterfrågan utgående från olika individers handlingsmöjligheter.
Northrop, Robert M.
core   +1 more source