Results 31 to 40 of about 29,233 (268)

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

FEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas, Brigitta Maruzs, Zsófia E. Kálmán, Tomas Klumpler, Gyula Batta, Bálint Péterfia, Zoltán Gáspári   +6 more
wiley   +1 more source

India's Baseline Plan for Nuclear Energy Self-Sufficiency. [PDF]

, 2009
India's nuclear energy strategy has traditionally strived for energy self-sufficiency, driven largely by necessity following trade restrictions imposed by the Nuclear Suppliers Group (NSG) following India's 'peaceful nuclear explosion' of 1974.
Bucher, R .G., Division, Nuclear Engineering   +1 more
core   +1 more source

A new theoretical performance analysis method considering longitudinal and transverse end effects for flat linear induction magnetohydrodynamic pumps

Frontiers in Nuclear Engineering
The flat linear induction pumps (FLIPs) are a class of driving devices that converts electromagnetic energy into mechanical energy of pumped liquid metal, which are widely used in the field of energy power and chemical industries.
Ming Ding, Chunwei Yang, Yifan Bai, Keming Bi, Xin Yan   +4 more
doaj   +1 more source

IAEA coordinated research project on nuclear data for charged-particle monitor reactions and medical isotope production

EPJ Web of Conferences, 2017
An IAEA coordinated research project was launched in December 2012 to establish and improve the nuclear data required to characterise charged-particle monitor reactions and extend data for medical radionuclide production.
Capote Roberto, Nichols Alan L., Nortier Francois Meiring, Carlson Brett V., Engle Jonathan W., Hermanne Alex, Hussain Mazhar, Ignatyuk Anatoly V., Kellett Mark A., Kibédi Tibor, Kim Guinyun, Kondev Filip G., Lebeda Ondrej, Luca Aurelian, Naik Haladhara, Nagai Yasuki, Spahn Ingo, Suryanarayana Saraswatula V., Tárkányi Ferenc T., Verpelli Marco   +19 more
doaj   +1 more source

From mice to humans—divergent strategies for intestinal homeostasis and regeneration

FEBS Letters, EarlyView.
Recent advances such as organoid genome editing, xenotransplantation, imaging, and whole‐genome sequencing have enabled direct studies of human intestinal stem cells (ISCs). These studies reveal species‐specific features, including slower ISC proliferation, distinct injury responses, slower somatic mutation accumulation in humans, and an inverse ...
Keiko Ishikawa, Shinya Sugimoto, Toshiro Sato   +2 more
wiley   +1 more source

The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers

Molecular Oncology, EarlyView.
The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce, Simone Bini, Marialuisa Sponziello, Giorgio Grani, Giulia Fiscon, Paola Paci, Lorenzo Farina, Rosa Falcone, Valentina Maggisano, Sebastiano Filetti, Cosimo Durante, Antonella Verrienti   +11 more
wiley   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Potential of heat pipe technology in nuclear seawater desalination

, 2009
The official published version of this article can be found at the link below.Heat pipe technology may play a decisive role in improving the overall economics, and public perception on nuclear desalination, specifically on seawater desalination.
Anastasov, V, Khamis, I, Jouhara, H
core   +1 more source

Development and Verification of CUPID-MSR Using the de Vahl Davis Natural-Convection Benchmark

Energies
This study provides the first systematic verification of the CUPID-MSR thermal–hydraulic code for molten-salt reactor applications, incorporating temperature-dependent thermophysical properties of two chloride-based molten salts, KCl–UCl3 and NaCl–MgCl2 ...
Rafał Stoga, Jae Ryong Lee, Han Young Yoon   +2 more
doaj   +1 more source

The CIELO collaboration: Progress in international evaluations of neutron reactions on Oxygen, Iron, Uranium and Plutonium

EPJ Web of Conferences, 2017
The CIELO collaboration has studied neutron cross sections on nuclides that significantly impact criticality in nuclear technologies – 16O, 56Fe, 235,8U and 239Pu – with the aim of improving the accuracy of the data and resolving previous discrepancies ...
Chadwick M.B., Capote R., Trkov A., Kahler A.C., Herman M.W., Brown D.A., Hale G.M., Pigni M., Dunn M., Leal L., Plompen A., Schillebeeck P., Hambsch F.-J., Kawano T., Talou P., Jandel M., Mosby S., Lestone J., Neudecker D., Rising M., Paris M., Nobre G.P.A., Arcilla R., Kopecky S., Giorginis G., Cabellos O., Hill I., Dupont E., Danon Y., Jing Q., Zhigang G., Tingjin L., Hanlin L., Xichao R., Haicheng W., Sin M., Bauge E., Romain P., Morillon B., Noguere G., Jacqmin R., Bouland O., De Saint Jean C., Pronyaev V.G., Ignatyuk A., Yokoyama K., Ishikawa M., Fukahori T., Iwamoto N., Iwamoto O., Kuneada S., Lubitz C.R., Palmiotti G., Salvatores M., Kodeli I., Kiedrowski B., Roubtsov D., Thompson I., Quaglioni S., Kim H.I., Lee Y.O., Koning A.J., Carlson A., Fischer U., Sirakov I.   +64 more
doaj   +1 more source