Results 31 to 40 of about 10,707,057 (260)

Implementation of functional expansion tally method and order selection strategy in Monte Carlo code RMC

Nuclear Engineering and Technology, 2021
The spatial distribution of neutron flux or reaction rate was calculated by cell or mesh tally in traditional Monte Carlo simulation. However, either cell or mesh tally leads to the increase of memory consumption and simulation time.
Zhenyu Wang, Shichang Liu, Ding She, Yang Su, Yixue Chen   +4 more
doaj   +1 more source

Investigating transcription factor dynamics in health and disease using FRAP

FEBS Letters, EarlyView.
FRAP analysis of GFP‐tagged transcription factors reveals how molecular mobility and target engagement change in response to drug treatment. By combining live‐cell imaging, quantitative model fitting, and statistical analysis, this approach uncovers transcription factor dynamics linked to disease mechanisms, providing a powerful framework for ...
Kannan Govindaraj, Carolina Vazquez Garzon, Jose Joaquin Velasco, Janine N. Post   +3 more
wiley   +1 more source

IAEA coordinated research project on nuclear data for charged-particle monitor reactions and medical isotope production

EPJ Web of Conferences, 2017
An IAEA coordinated research project was launched in December 2012 to establish and improve the nuclear data required to characterise charged-particle monitor reactions and extend data for medical radionuclide production.
Capote Roberto, Nichols Alan L., Nortier Francois Meiring, Carlson Brett V., Engle Jonathan W., Hermanne Alex, Hussain Mazhar, Ignatyuk Anatoly V., Kellett Mark A., Kibédi Tibor, Kim Guinyun, Kondev Filip G., Lebeda Ondrej, Luca Aurelian, Naik Haladhara, Nagai Yasuki, Spahn Ingo, Suryanarayana Saraswatula V., Tárkányi Ferenc T., Verpelli Marco   +19 more
doaj   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

A new theoretical performance analysis method considering longitudinal and transverse end effects for flat linear induction magnetohydrodynamic pumps

Frontiers in Nuclear Engineering
The flat linear induction pumps (FLIPs) are a class of driving devices that converts electromagnetic energy into mechanical energy of pumped liquid metal, which are widely used in the field of energy power and chemical industries.
Ming Ding, Chunwei Yang, Yifan Bai, Keming Bi, Xin Yan   +4 more
doaj   +1 more source

Ligand‐dependent transcriptional heterogeneity in cell cycle gene expression delays G1/S entry

FEBS Letters, EarlyView.
EGF and HRG induce distinct G1/S progression programs in ErbB2‐amplified BT474 breast cancer cells. Despite activating the potent ErbB2–ErbB3 heterodimer, HRG does not accelerate cell‐cycle entry. Instead, EGF promotes earlier restriction‐point passage via ERK–FOS signaling, whereas HRG activates the AKT–MYC axis, driving transcriptional heterogeneity ...
Ririn Rahmala Febri, Ayaka Nagasato‐Ichikawa, Keita Iida, Shuhei Kimura, Akira Imamoto, Mariko Okada   +5 more
wiley   +1 more source

Safety and security [PDF]

, 2012
This paper is the sixth in a series of 8 that make up the evidence base for SDC report 'The role of nuclear power in a low carbon economy'.The document covers accident risk in plants (including a historical review of accidents), threats from design ...
AMEC NNC Limited, Large & Associates, Sustainable Development Commission   +2 more
core   +2 more sources

Emerging experimental and computational methods for studying redox‐regulated structural transitions

FEBS Letters, EarlyView.
Redox reactions can reshape proteins and alter how they behave in cells, with important consequences for health and disease. This review explores emerging experimental and computational approaches for discovering these redox‐sensitive protein switches, revealing their structural effects, and predicting their behavior, opening new opportunities to ...
Tasneem Rass, Dana Reichmann, Gábor Erdős   +2 more
wiley   +1 more source

Synergistic perspectives—How single‐molecule biophysics complement biochemical understanding

FEBS Letters, EarlyView.
In this review, we discuss how ensemble biochemistry and single‐molecule approaches are complementary, outline commonly used single‐molecule techniques, and illustrate their relevance through two representative case studies: chromatin organization by SMC complexes and pathway choice during DNA double‐strand break repair.
Sara De Bragança, Eline L. Jansen, Jorine M. Eeftens   +2 more
wiley   +1 more source

Development and Verification of CUPID-MSR Using the de Vahl Davis Natural-Convection Benchmark

Energies
This study provides the first systematic verification of the CUPID-MSR thermal–hydraulic code for molten-salt reactor applications, incorporating temperature-dependent thermophysical properties of two chloride-based molten salts, KCl–UCl3 and NaCl–MgCl2 ...
Rafał Stoga, Jae Ryong Lee, Han Young Yoon   +2 more
doaj   +1 more source