Results 41 to 50 of about 195,424 (265)

Quantum entanglement and spin control in silicon nanocrystal [PDF]

, 2012
Selective coherence control and electrically mediated exchange coupling of single electron spin between triplet and singlet states using numerically derived optimal control of proton pulses is demonstrated.
Berec, Vesna
core   +3 more sources

Valosin‐containing protein counteracts ATP‐driven dissolution of FUS condensates through its ATPase activity in vitro

FEBS Letters, EarlyView.
Biomolecular condensates formed by fused in sarcoma (FUS) are dissolved by high ATP concentrations yet persist in cells. Using a reconstituted system, we demonstrate that valosin‐containing protein (VCP), an AAA+ ATPase, counteracts ATP‐driven dissolution of FUS condensates through its D2 ATPase activity.
Hitomi Kimura, Shin‐ichi Tate, Kyota Yasuda   +2 more
wiley   +1 more source

Basroparib inhibits YAP‐driven cancers by stabilizing angiomotin

Molecular Oncology, EarlyView.
Basroparib, a selective tankyrase inhibitor, suppresses Wnt signaling and attenuates YAP‐driven oncogenic programs by stabilizing angiomotin. It promotes AMOT–YAP complex formation, enforces cytoplasmic YAP sequestration, inhibits YAP/TEAD transcription, and sensitizes YAP‐active cancers, including KRAS‐mutant colorectal cancer, to MEK inhibition.
Young‐Ju Kwon, Dong Young Kim, Yuna Kim, Uk‐Il Kim, Jae‐Sung Kim   +4 more
wiley   +1 more source

Identification of serum protein biomarkers for pre‐cancerous lesions associated with pancreatic ductal adenocarcinoma

Molecular Oncology, EarlyView.
This work identified serum proteins associated with pancreatic epithelial neoplasms (PanINs) and early‐stage PDAC. Proteomics screens assessed genetically engineered mice with abundant PanINs, KPC mice (Lox‐STOP‐Lox‐KrasG12D/+ Lox‐STOP‐Lox‐Trp53R172H/+ Pdx1‐Cre) before PDAC development and also early‐stage PDAC patients (n = 31), compared to benign ...
Hannah Mearns, Jaclyn S. Long, Sergio Lilla, Kelly Hodge, Marcus J. G. W. Ladds, Colin Nixon, Paula Fernández‐Palanca, Sara Zanivan, Pilar Acedo, Stephen P. Pereira, Kevin M. Ryan   +10 more
wiley   +1 more source

Development and Verification of CUPID-MSR Using the de Vahl Davis Natural-Convection Benchmark

Energies
This study provides the first systematic verification of the CUPID-MSR thermal–hydraulic code for molten-salt reactor applications, incorporating temperature-dependent thermophysical properties of two chloride-based molten salts, KCl–UCl3 and NaCl–MgCl2 ...
Rafał Stoga, Jae Ryong Lee, Han Young Yoon   +2 more
doaj   +1 more source

The CIELO collaboration: Progress in international evaluations of neutron reactions on Oxygen, Iron, Uranium and Plutonium

EPJ Web of Conferences, 2017
The CIELO collaboration has studied neutron cross sections on nuclides that significantly impact criticality in nuclear technologies – 16O, 56Fe, 235,8U and 239Pu – with the aim of improving the accuracy of the data and resolving previous discrepancies ...
Chadwick M.B., Capote R., Trkov A., Kahler A.C., Herman M.W., Brown D.A., Hale G.M., Pigni M., Dunn M., Leal L., Plompen A., Schillebeeck P., Hambsch F.-J., Kawano T., Talou P., Jandel M., Mosby S., Lestone J., Neudecker D., Rising M., Paris M., Nobre G.P.A., Arcilla R., Kopecky S., Giorginis G., Cabellos O., Hill I., Dupont E., Danon Y., Jing Q., Zhigang G., Tingjin L., Hanlin L., Xichao R., Haicheng W., Sin M., Bauge E., Romain P., Morillon B., Noguere G., Jacqmin R., Bouland O., De Saint Jean C., Pronyaev V.G., Ignatyuk A., Yokoyama K., Ishikawa M., Fukahori T., Iwamoto N., Iwamoto O., Kuneada S., Lubitz C.R., Palmiotti G., Salvatores M., Kodeli I., Kiedrowski B., Roubtsov D., Thompson I., Quaglioni S., Kim H.I., Lee Y.O., Koning A.J., Carlson A., Fischer U., Sirakov I.   +64 more
doaj   +1 more source

Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma

Molecular Oncology, EarlyView.
Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra, Lucca Paolo Hsu Helmich, Daniel Rodrigues de Bastos, Laura Sichero, Patrícia Savio de Araujo‐Souza, Fabio Passetti, Luisa Lina Villa   +6 more
wiley   +1 more source

Specifications for a coupled neutronics thermal-hydraulics SFR test case [PDF]

, 2017
Coupling neutronics/thermal-hydraulics calculations for the design of nuclear reactors is a growing trend in the scientific community. This approach allows to properly represent the mutual feedbacks between the neutronic distribution and the thermal ...
TASSONE, ALESSANDRO
core   +1 more source

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Internationalization of the Nuclear Fuel Cycle: Goals, Strategies, and Challenges [PDF]

, 2008
Presents U.S. and Russian experts' analyses of and recommendations on options for securing the international nuclear fuel cycle, including the provision of fuel to countries pursuing nuclear power to dissuade them from building uranium enrichment ...

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