Results 121 to 130 of about 717,626 (259)

A new flow chip in combination with multiphoton microscopy as a protocol for longitudinal 3D imaging of tissue calcification under shear stress

FEBS Open Bio, EarlyView.
Miniaturized flow chip platform enabling continuous perfusion and longitudinal multiphoton 3D imaging of vascular smooth muscle cell constructs under physiological flow. Brightfield imaging guides region selection, while CellTracker Green and mRuby‐labeled fetuin‐A visualize cells and mineral deposition, respectively. Magnesium supplementation markedly
Vytautas Kučikas, Aaron D. Morgan, Ignas Čiurlionis, Christian Böhm, Stefan Jockenhövel, Willi Jahnen‐Dechent, Marc A. M. J. van Zandvoort   +6 more
wiley   +1 more source

Embedded cell-only bioprinting to engineer structurally aligned meniscal fibrocartilage. [PDF]

Mater Today Bio
Karam AS, Kronemberger GS, Chattahy K, Sanchez-Amador DE, Monaghan MG, Kelly DJ.   +5 more
europepmc   +1 more source

Malformin A1–mediated cytotoxicity in ovarian cancer cells occurs through pyroptosis and autophagy

FEBS Open Bio, EarlyView.
This study investigated the effects of the natural compound Malformin A1 (MA1) on the cytoskeleton that regulates cell proliferation and migration. Disruption of the cytoskeleton can impair these processes and promote cancer cell death. MA1 disrupted cytoskeletal organization, induced DNA damage, inflammation, activated autophagy, and pyroptosis ...
Nada Abdullah Hassan, Ikram A. Burney, Shika Hanif Malgundkar, Siva Ramamoorthy, Ressin Varghese, Mohamed A. Al‐Kindi, Hamad Al Riyami, Shadia Al Bahlani, Sergey Dobretsov, Syed Imran Hassan, Benjamin K. Tsang, Yahya Tamimi   +11 more
wiley   +1 more source

ATZ‐1 promotes DNA replication efficiency to maintain normal meiotic function

FEBS Open Bio, EarlyView.
Absence of ATZ‐1 interferes with meiotic DNA replication and cell cycle function via CHK‐1. This causes downstream defects associated with DNA damage and genomic integrity. Taken together, this study suggests that ATZ‐1 influences DNA replication efficiency and cell cycle function to maintain normal meiotic function.
Taylin E. Gourley, Luke W. Molesworth, Nethma H. Waduge, Fahimeh Eskandari, Peter R. Boag, Gregory M. Davis   +5 more
wiley   +1 more source

Retraction Note: A hybrid LSTM random forest model with grey wolf optimization for enhanced detection of multiple bearing faults. [PDF]

Sci Rep
Djaballah S, Saidi L, Meftah K, Hechifa A, Bajaj M, Zaitsev I.   +5 more
europepmc   +1 more source

Structural studies and functional engineering of NanX: an anhydro‐sialic acid transporter from Escherichia coli

FEBS Open Bio, EarlyView.
Biophysical characterisation shows that NanX, a membrane transport protein from the major facilitator superfamily (MFS), forms both monomers and dimers after purification. AlphaFold modelling and substrate docking provide information on residues likely involved in substrate recognition for NanX and another MFS member, NanT.
Michael C. Newton‐Vesty, Kelsi R. Hall, Zachary D. Tillett, Liam S. Turk, James S. Davies, Michael J. Currie, Hamish G. Brown, Sepideh Valimehr, Peter D. Mace, Andrew E. Whitten, Santosh Panjikar, Eric Hanssen, Rachel A. North, Renwick C.J. Dobson   +13 more
wiley   +1 more source

Nuclear Enlargement as a Histological Hallmark of Skeletal Muscle Aging, Revealed by Deep Learning-Driven Analysis and Validated in Inflammatory Myopathies. [PDF]

Aging Cell
Dao T, Nguyen TT, Hoang GM, Park J, Jo Y, Ngoc TH, Pho DH, Minh DT, Ton EA, Lee S, Kim HJ, Dung VC, Kim JG, Ryu D.   +13 more
europepmc   +1 more source

Adenosine triphosphate as a modulator of protein interactions and stability

FEBS Open Bio, EarlyView.
ATP is best known as the cell's energy currency, but it also shapes how proteins fold, interact, aggregate and form biomolecular condensates. This review explains the emerging physical principles behind these effects, including weak binding to charged protein regions, magnesium‐dependent behaviour and concentration‐dependent control of protein ...
Shuyuan Tan, Robin Curtis
wiley   +1 more source

Renaissance of Nuclear Engineering; A proposal of future nuclear engineering studies in universities.

Journal of the Atomic Energy Society of Japan / Atomic Energy Society of Japan, 1997
Haruki MADARAME, Yoshiaki OKA, Yosuke KATSUMURA, Naoto SEKIMURA, Seiichi KOSHIZUKA, Kenzo MIYA, Kazuyuki DEMACHI, Shinya NAGASAKI, Satoru TANAKA, Takayuki TERAI, Mitsuru UESAKA, Hiroyuki TAKAHASHI, Koji OKAMOTO   +12 more
openaire   +3 more sources

Electroconductive Soft Microcarriers for Suspension Culture of Skeletal Muscle Cells. [PDF]

Macromol Biosci
Balgouri AS, Askari E, Razzaghi M, Alizadeh Sardroud H, Barough MS, Tekumalla S, Akbari M.   +6 more
europepmc   +1 more source