Results 91 to 100 of about 138,674 (288)

Spherical Skin Model: Stratified Co‐Culture of Fibroblasts and Keratinocytes on Spherical Beads Toward Compound Screening

Advanced Healthcare Materials, EarlyView.
Models of the human skin must combine the relevant biological contents and suitable biomaterials with the correct spatial organization. Performing compound screening on such in vitro models also requires fast and reproducible production methods of the models.
Elisa Lenzi, Nadia Vertti‐Quintero, Julien Husson, Anne‐Laure Bulteau, Carine Nizard, Karl Pays, Sébastien Sart, Charles N. Baroud   +7 more
wiley   +1 more source

Protein kinase C activity modulates nuclear Lamin A/C dynamics in HeLa cells

Scientific Reports
The nuclear lamina serves important functions in the nucleus, providing structural support to the nuclear envelope and contributing to chromatin organization. The primary proteins that constitute the lamina are nuclear lamins whose functions are impacted
Chase C. Wesley, Dallin V. North, Daniel L. Levy   +2 more
doaj   +1 more source

Nuclear envelope impairment is facilitated by the herpes simplex virus 1 Us3 kinase [version 1; peer review: 2 approved]

F1000Research, 2019
Background: Capsids of herpes simplex virus 1 (HSV-1) are assembled in the nucleus, translocated either to the perinuclear space by budding at the inner nuclear membrane acquiring tegument and envelope, or released to the cytosol in a “naked” state via ...
Peter Wild, Sabine Leisinger, Anna Paula de Oliveira, Jana Doehner, Elisabeth M. Schraner, Cornel Fraevel, Mathias Ackermann, Andres Kaech   +7 more
doaj   +1 more source

Antimicrobial Efficacy of a Taurolidine‐Based Antimicrobial Compound on Contaminated Surfaces Simulated in a Standardized 4‐Field Test

Advanced Healthcare Materials, EarlyView.
As implantable medical devices become indispensable to modern medicine, a silent threat grows alongside them: device‐associated infections. Despite decades of antibiotic innovation, infection rates keep climbing, costing lives and billions in healthcare expenses.
Benito Baldauf, Hendrik Bonnemeier, Ernest W. Lau, Jana Hummel, Reinhard Vonthein, Ojan Assadian   +5 more
wiley   +1 more source

The overexpression of nuclear envelope protein Lap2β induces endoplasmic reticulum reorganisation via membrane stacking

Biology Open, 2012
Summary Some nuclear envelope proteins are localised to both the nuclear envelope and the endoplasmic reticulum; therefore, it seems plausible that even small amounts of these proteins can influence the organisation of the endoplasmic reticulum. A simple
Ekaterina G. Volkova, Sergey S. Abramchuk, Eugene V. Sheval   +2 more
doaj   +1 more source

Simian virus 40 induces lamin A/C fluctuations and nuclear envelope deformation during cell entry [PDF]

, 2011
Veronika Butin‐Israeli, Orly Ben-nun-Shaul, Idit Kopatz, Stephen A. Adam, Takeshi Shimi, Robert D. Goldman, Ariella Oppenheim   +6 more
openalex   +1 more source

Redefining Therapies for Drug‐Resistant Tuberculosis: Synergistic Effects of Antimicrobial Peptides, Nanotechnology, and Computational Design

Advanced Healthcare Materials, EarlyView.
Antimicrobial peptide (AMP)‐loaded nanocarriers provide a multifunctional strategy to combat drug‐resistant Mycobacterium tuberculosis. By enhancing intracellular delivery, bypassing efflux pumps, and disrupting bacterial membranes, this platform restores phagolysosome fusion and macrophage function.
Christian S. Carnero Canales, Jessica Ingrid Marquez Cazorla, Renzo Marianito Marquez Cazorla, Aline Martins dos Santos, Jonatas Lobato Duarte, Letícia Oliveira Catarin Nunes, Túlio Custódio Reis, Lara Cerazi Salvador, Norival Alves Santos‐Filho, Rafael Miguel Sábio, Hélder A. Santos, Fernando Rogério Pavan   +11 more
wiley   +1 more source

Radiation Effects in Electret Organic Thin‐Film Transistors Due to High Flux and High Dose X‐Ray Irradiation

Advanced Materials, EarlyView.
Electret‐style organic thin‐film transistors are evaluated for synchrotron X‐ray dosimetry at ultra‐high dose rates, showing promising performance and agreement with standard detectors. XPS and NEXAFS reveal radiation‐induced oxidation and Fermi level shifts in pentacene and polystyrene, correlating with reduced charge carrier mobility and providing ...
Alexandria Mitchell, Jessie A. Posar, James Cayley, Georgia York, Michael Lerch, Attila J. Mozer, Igor Píš, Elena Magnano, Luca Tosti, Maddalena Pedio, Alasdair Syme, Ian G. Hill, Marco Petasecca   +12 more
wiley   +1 more source

Cytosol dependent membrane fusion in ER, nuclear envelope and nuclear pore assembly [PDF]

, 2010
E. R. Rafikova, Kamran Melikov, Leonid Chernomordik   +2 more
openalex   +1 more source

Bacteria‐Responsive Nanostructured Drug Delivery Systems for Targeted Antimicrobial Therapy

Advanced Materials, EarlyView.
Bacteria‐responsive nanocarriers are designed to release antimicrobials only in the presence of infection‐specific cues. This selective activation ensures drug release precisely at the site of infection, avoiding premature or indiscriminate release, and enhancing efficacy.
Guillermo Landa, Gracia Mendoza, Silvia Irusta, Manuel Arruebo   +3 more
wiley   +1 more source