Results 121 to 130 of about 401,673 (204)
Biochemistry and Biophysics Reports, 2023 We present the influence of treating progeroid fibroblasts with two modified antisense oligonucleotides (ONs) on the nuclear envelope. Two modified ONs were designed to block ribosome binding during translation and spliceosome binding at the cryptic ...
Asmaa Abdelrahman +3 more
doaj
Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy
Cells, 2018 LMNA linked-Emery-Dreifuss muscular dystrophy (EDMD2) is a rare disease characterized by muscle weakness, muscle wasting, and cardiomyopathy with conduction defects.
Elisabetta Mattioli +5 more
doaj +1 more source
Morphological Characterization of the Radiation Sensitive Cell Line, XRS-5 [PDF]
, 1993 Morphometric analysis was performed on the radiation sensitive Chinese hamster ovary (CHO) xrs-5 cell line, reverting xrs-5 cells and parental K1 cells. Several ultrastructural parameters (increased nuclear envelope membrane separation, cell and nuclear ...
Korte, Carol C., Yasui, Linda S.
core +1 more source
BMC Neuroscience, 2007 Background In hippocampal neurons, nuclear calcium signaling is important for learning- and neuronal survival-associated gene expression. However, it is unknown whether calcium signals generated by neuronal activity at the cell membrane and propagated to
Bading Hilmar, Eder Anja
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Why Do Stars Turn Red? I. Post-Main-Sequence Expansion Mechanism [PDF]
arXivWe revisit the long-standing question: Why do post-main-sequence stars evolve into red giants (RGs) or red supergiants (RSGs)? Using the 1D stellar evolution code MESA, we perform numerical experiments to compare stellar models that successfully transition into RGs/RSGs with those that remain blue.
arxiv
Nuclear envelopathies: a complex LINC between nuclear envelope and pathology
Orphanet Journal of Rare Diseases, 2017 Since the identification of the first disease causing mutation in the gene coding for emerin, a transmembrane protein of the inner nuclear membrane, hundreds of mutations and variants have been found in genes encoding for nuclear envelope components ...
Alexandre Janin +4 more
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Forming a clumpy circumstellar material in energetic pre-supernova activity [PDF]
arXivWe demonstrate by three-dimensional hydrodynamical simulations of energy deposition into the envelope of a red supergiant (RSG) model the inflation of a Rayleigh-Taylor unstable envelope that forms a compact clumpy circumstellar material (CSM).
arxiv
Meiotic cellular rejuvenation is coupled to nuclear remodeling in budding yeast. [PDF]
, 2019 Production of healthy gametes in meiosis relies on the quality control and proper distribution of both nuclear and cytoplasmic contents. Meiotic differentiation naturally eliminates age-induced cellular damage by an unknown mechanism.
Chetlapalli, Keerthana +6 more
core +1 more source
Thermonuclear Heating of Accreting Neutron Stars [PDF]
arXivWe describe a new method to incorporate thermonuclear heating in the envelope of accreting neutron star into long term simulations of their thermal evolution. We obtain boundary conditions for the heat exchange between the envelope and the crust based on stationary models which include nuclear burning and validate these values comparing to the results ...
arxiv
EBioMedicine, 2020 Background: As genome-wide approaches prove difficult with genetically heterogeneous orphan diseases, we developed a new approach to identify candidate genes.
Peter Meinke +12 more
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