Results 131 to 140 of about 146,588 (257)

Phase Separation of SF3B1 Serves as a Critical Post‐Transcriptional Regulator During Early Mouse Embryogenesis

open access: yesAdvanced Science, EarlyView.
Phase separation of SF3B1 acts as a key regulatory mechanism for dynamic alternative splicing throughout early mouse embryogenesis. Its absence triggers extensive splicing errors, which induce persistent DNA damage, defective cell cycle progression, and failed cell lineage commitment, and ultimately hinder the normal growth and development of ...
Kang Zhao   +15 more
wiley   +1 more source

Fast Programming of in‐Plane Hyperbolic Phonon Polariton Optics through Van der Waals Crystals Using the Phase‐Change Material In3SbTe2

open access: yesAdvanced Science, EarlyView.
Launching structures for in‐plane hyperbolic polaritons in α‐MoO3 are optically programmed through already deposited flakes into the phase‐change material In3SbTe2. Precise alignment with the flake's crystal axes, focusing of polaritons by an optically programmed disk, and a first experimental realization toward a nanocavity for in‐plane hyperbolic ...
Lina Jäckering   +10 more
wiley   +1 more source

RanGAP1 coordinates the ER-lamina interface to drive de novo nuclear envelope reassembly in mouse embryos. [PDF]

open access: yesSci Adv
Zhang XJ   +9 more
europepmc   +1 more source

Organic Electrochemical Transistors for Neuromorphic Bioelectronics: Materials and Manufacturing Technologies

open access: yesAdvanced Science, EarlyView.
Organic electrochemical transistors bridge biological ionic signaling and neuromorphic computation through volumetric electrochemical gating. This review connects Organic mixed ionic–electronic conductor materials, device architectures, and manufacturing technologies to show how geometry, ion transport, and fabrication strategies program plasticity ...
Hyunjin Lee   +5 more
wiley   +1 more source

Periostin‐CCL3 Feedforward Signaling Loop Promotes Cardiac Fibrosis and Cardiomyocyte Necroptosis in Arrhythmogenic Cardiomyopathy

open access: yesAdvanced Science, EarlyView.
POSTN‐CCL3 signaling forms a feed‐forward circuit between cardiomyocytes and cardiac myofibroblasts in arrhythmogenic cardiomyopathy. POSTN activates JNK/RIP3‐dependent necroptotic signaling and JNK/ETS2‐induced CCL3 expression in cardiomyocytes. In turn, CCL3‐CCR5 signaling in cardiac myofibroblasts activates NF‐κB/p65 and promotes POSTN expression ...
Tiantian Wu   +12 more
wiley   +1 more source

The nuclear lamins and the nuclear envelope.

open access: yesCellular & molecular biology letters, 2003
The cell nucleus is separated from the rest of the cell by the nuclear envelope. The nuclear envelope, nuclear envelope proteins and nuclear lamina organise the structure of the entire nucleus and the chromatin via a myriad of interactions. These interactions are dynamic, change with the change (progress) of the cell cycle, with cell differentiation ...
openaire   +1 more source

Customized Itinerant Frequency Combs by Cascaded Nonlinear Effects

open access: yesAdvanced Science, EarlyView.
A cascaded third‐order nonlinear system generates an itinerant frequency comb with the comb center frequency decoupled from the cavity resonance. This enables arbitrary spectral scaling, flexible spacing adjustments, and real‐time central‐frequency engineering, allowing comb splicing and subdivision. The resulting versatility and reconfigurability open
Yi Wang   +8 more
wiley   +1 more source

Patching up the nucleus: a novel role for PMLII in nuclear envelope stability. [PDF]

open access: yesNucleic Acids Res
Janssen AFJ   +6 more
europepmc   +1 more source

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