Results 161 to 170 of about 2,002,555 (370)

SOME OBSERVATIONS ON THE NUCLEAR ENVELOPE [PDF]

open access: bronze, 1960
W. Gordon Whaley   +2 more
openalex   +1 more source

Exploring Phonon Interference: Insights From a Nano‐Scale Silicon Double Slit Atomistic Simulation

open access: yesAdvanced Theory and Simulations, EarlyView.
Classical Waves at the Atomic Scale: Molecular Dynamics Reveal Phonon Interference in Silicon Nanostructures. Abstract In this study, the classic double‐slit experiment, originally developed for light waves is successfully adapted, to investigate the behavior of phonons in crystalline silicon.
Efstratios Nikidis   +5 more
wiley   +1 more source

Nuclear envelope impairment is facilitated by the herpes simplex virus 1 Us3 kinase [version 1; peer review: 2 approved]

open access: yesF1000Research, 2019
Background: Capsids of herpes simplex virus 1 (HSV-1) are assembled in the nucleus, translocated either to the perinuclear space by budding at the inner nuclear membrane acquiring tegument and envelope, or released to the cytosol in a “naked” state via ...
Peter Wild   +7 more
doaj   +1 more source

Cathepsin K Aggravates Pulmonary Fibrosis Through Promoting Fibroblast Glutamine Metabolism and Collagen Synthesis

open access: yesAdvanced Science, EarlyView.
CTSK plays a critical role in pulmonary fibrosis. Excessive CTSK accumulation interacts with SNX9 to enhance TGF‐β1‐induced SMAD3 activation and GLS1 expression in fibroblasts, driving glutamine metabolism for collagen biosynthesis and exacerbating pulmonary fibrosis.
Mengting Chen   +10 more
wiley   +1 more source

Samp1 Mislocalization in Emery-Dreifuss Muscular Dystrophy

open access: yesCells, 2018
LMNA linked-Emery-Dreifuss muscular dystrophy (EDMD2) is a rare disease characterized by muscle weakness, muscle wasting, and cardiomyopathy with conduction defects.
Elisabetta Mattioli   +5 more
doaj   +1 more source

Large Scale RNAi Reveals the Requirement of Nuclear Envelope Breakdown for Nuclear Import of Human Papillomaviruses

open access: yesPLoS Pathogens, 2014
A two-step, high-throughput RNAi silencing screen was used to identify host cell factors required during human papillomavirus type 16 (HPV16) infection.
I. Aydin   +11 more
semanticscholar   +1 more source

Nanoscale Curvature Regulates YAP/TAZ Nuclear Localization Through Nuclear Deformation and Rupture

open access: yesAdvanced Science, EarlyView.
This study uses experiments and biophysical modeling to examine the response and adaptation of cells to nanoscale topography of surfaces. It is shown that cytoskeletal assembly and nuclear localization of transcription regulatory factors such as yes‐associated protein (YAP) and transcriptional coactivator with PDZ‐binding motif (TAZ) can be tuned by ...
Emmet A. Francis   +7 more
wiley   +1 more source

Calcium signals can freely cross the nuclear envelope in hippocampal neurons: somatic calcium increases generate nuclear calcium transients

open access: yesBMC Neuroscience, 2007
Background In hippocampal neurons, nuclear calcium signaling is important for learning- and neuronal survival-associated gene expression. However, it is unknown whether calcium signals generated by neuronal activity at the cell membrane and propagated to
Bading Hilmar, Eder Anja
doaj   +1 more source

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