Prioritizing Feasible and Impactful Actions to Enable Secure AI Development and Use in Biology
Biotechnology and Bioengineering, EarlyView.ABSTRACT As artificial intelligence continues to enhance biological innovation, the potential for misuse must be addressed to fully unlock the potential societal benefits. While significant work has been done to evaluate general‐purpose AI and specialized biological design tools (BDTs) for biothreat creation risks, actionable steps to mitigate the risk
Josh Dettman +4 more
wiley +1 more source
The Second Selectivity of Taxanes to Malignant Cells --- Nuclear Envelope Malleability. [PDF]
J CancerXu XX, Smith ER.
europepmc +1 more source
Enhanced strategies for cuproptosis‐like death in bacterial infection treatment
BMEMat, EarlyView.This review summarizes and examines the molecular mechanisms underlying cuproptosis‐like death. Furthermore, multi‐strategy efficacy enhancement and potential enhancement approaches are analyzed. Abstract Copper, a classical antibacterial metal, has long been of interest and widely used in medical and public health applications.
Wenqi Wang +7 more
wiley +1 more source
Nuclear envelope-associated lipid droplets are enriched in cholesteryl esters and increase during inflammatory signaling. [PDF]
EMBO JSzkalisity Á +10 more
europepmc +1 more source
Effect of Precursor Structure on Pore Evolution of Pitch‐Derived Porous Carbon Nanoarchitectonics
Carbon and Hydrogen, EarlyView.Precursor microstructure–regulated activation and pore evolution in pitch‐derived porous carbon, demonstrating the superior nanoarchitectonics at moderate mesophase content. ABSTRACT Developing high‐performance porous carbons (PCs) requires precise microstructural control, which can be effectively understood within the framework of nanoarchitectonics ...
Yajie Duan +4 more
wiley +1 more source
At the nucleus of cancer: how the nuclear envelope controls tumor progression. [PDF]
MedComm (2020)Paganelli F +6 more
europepmc +1 more source
A [3]Rotaxane Containing {Ti7Ga} Rings Linking CuII: Synthesis, Structure, and Spectroscopic Studies
Chemistry – A European Journal, EarlyView.Extended hybrid inorganic‐organic [2]‐ and [3]‐rotaxanes are reported based on heterometallic rings with threads that link CuII complexes; the crystal structures are reported, and the solution behavior is investigated by double electron electron resonance spectroscopy methods.
Selena J. Lockyer +7 more
wiley +1 more source
Chemistry – A European Journal, EarlyView.The introduction outlines the review scope. Microbial cell factories as living drugs cover host–gut microbiota, bacteria, yeast, and other microbial systems, with comparative host advantages. Engineering strategies include synthetic circuits, quorum sensing, and memory.
Cemile Elif Özçelik +3 more
wiley +1 more source
Boron Neutron Capture Therapy at a Crossroads: Translational Gap and Emerging Delivery Agents
Chemistry – A European Journal, EarlyView.This review surveys recent advances in boron delivery agents for BNCT, emphasizing the shift from classical small molecules to multifunctional nanocarriers and theranostic systems. By integrating targeting, imaging, and therapy, next‐generation boron compounds aim to bridge the gap between (bio)chemical innovation and clinical translation.
Christoph Selg, Evamarie Hey‐Hawkins
wiley +1 more source
Phosphorylation of Lamin A/C regulates the structural integrity of the nuclear envelope. [PDF]
J Biol ChemLiu S +8 more
europepmc +1 more source