Results 271 to 280 of about 96,685 (288)
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Biophysics of the Nuclear Envelope
1995Publisher Summary The structural intricacy of the nuclear pore complex, and the large number of proteins that it contains, suggests that the nuclear pore is not simply a water-filled hole. It is a coupled transporter for ions and macromolecules. This chapter discusses that the nucleus can partition ions, the nuclear envelope maintains a resting ...
Louis J. DeFelice, Michele Mazzanti
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At the nuclear envelope of bone mechanobiology
Bone, 2021The nuclear envelope and nucleoskeleton are emerging as signaling centers that regulate how physical information from the extracellular matrix is biochemically transduced into the nucleus, affecting chromatin and controlling cell function. Bone is a mechanically driven tissue that relies on physical information to maintain its physiological function ...
Birks, Scott, Uzer, Gunes
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The nuclear envelope, lamins and nuclear assembly
Current Opinion in Cell Biology, 2002The nuclear lamina is composed of both A- and B-type lamins and lamin-binding proteins. Many lamin-binding proteins are integral proteins of the inner nuclear membrane. Lamins and inner nuclear membrane proteins are important for a variety of cell functions, including nuclear assembly, replication, transcription, and nuclear integrity.
James M. Holaska +2 more
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Science, 1953 Electrical Dimension of the Nuclear Envelope
Physiological Reviews, 2001Eukaryotic chromosomes are confined to the nucleus, which is separated from the rest of the cell by two concentric membranes known as the nuclear envelope (NE). The NE is punctuated by holes known as nuclear pore complexes (NPCs), which provide the main pathway for transport of cellular material across the nuclear-cytoplasmic boundary.
M. MAZZANTI +2 more
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Current Opinion in Cell Biology, 1992
The past 18 months have seen significant advances in our knowledge of the constituents of the nuclear envelope, their interactions during interphase and the mechanisms involved in their mitotic dynamics. Although most of the new data are in general agreement with, and contribute detail to, our traditional image of the nuclear envelope, a few ...
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The past 18 months have seen significant advances in our knowledge of the constituents of the nuclear envelope, their interactions during interphase and the mechanisms involved in their mitotic dynamics. Although most of the new data are in general agreement with, and contribute detail to, our traditional image of the nuclear envelope, a few ...
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2019
The nuclear envelope is a double membrane sheath made up of two lipid bilayers—an outer and an inner membrane. The inner surface of the inner membrane is associated with a meshwork of filaments made up of lamins and of lamin-associated proteins that constitute the lamina. A substantial portion of the genome contacts the lamina through lamina-associated
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The nuclear envelope is a double membrane sheath made up of two lipid bilayers—an outer and an inner membrane. The inner surface of the inner membrane is associated with a meshwork of filaments made up of lamins and of lamin-associated proteins that constitute the lamina. A substantial portion of the genome contacts the lamina through lamina-associated
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2008
The nuclear envelope is an important but poorly studied dynamic mem- brane system in plants. In particular, surprisingly little is known about the proteins of the higher plant nuclear envelope and their interactions. While structurally similar to the nuclear envelope of other kingdoms, unique properties suggest significant differences.
Katja Graumann +3 more
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The nuclear envelope is an important but poorly studied dynamic mem- brane system in plants. In particular, surprisingly little is known about the proteins of the higher plant nuclear envelope and their interactions. While structurally similar to the nuclear envelope of other kingdoms, unique properties suggest significant differences.
Katja Graumann +3 more
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Action of insulin at the nuclear envelope
Molecular and Cellular Biochemistry, 1991Insulin binding sites are present on purified nuclear envelopes from liver and other tissues, and EM autoradiographs and other types of studies indicate that insulin can enter intact target cells and interact with several types of intracellular membranes, including the nuclear envelope.
GOLDFINE ID +4 more
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Ion Permeability of the Nuclear Envelope
Physiology, 1998The nuclear envelope mediates nucleocytoplasmic communication. Nuclear pores transport proteins and RNA into and out of the nucleus. The pore is believed to allow free ion diffusion. Using an electrophysiological approach, we show the possible semipermeable properties of the envelope.
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