Results 51 to 60 of about 2,002,555 (370)
Nuclear envelope deformation controls cell cycle progression in response to mechanical force
EMBO Reports, 2019 The shape of the cell nucleus can vary considerably during developmental and pathological processes; however, the impact of nuclear morphology on cell behavior is not known. Here, we observed that the nuclear envelope flattens as cells transit from G1 to
Julien Aureille +10 more
semanticscholar +1 more source
An update on nuclear calcium signalling [PDF]
, 2009 Over the past 15 years or so, numerous studies have sought to characterise how nuclear calcium (Ca2+) signals are generated and reversed, and to understand how events that occur in the nucleoplasm influence cellular Ca2+ activity, and vice versa. In this
Bootman, Martin D. +4 more
core +1 more source
Protein phosphatases at the nuclear envelope [PDF]
Biochemical Society Transactions, 2018 The nuclear envelope (NE) is a unique topological structure formed by lipid membranes (Inner and Outer Membrane: IM and OM) interrupted by open channels (Nuclear Pore complexes). Besides its well-established structural role in providing a physical separation between the genome and the cytoplasm and regulating the exchanges between the two cellular ...
Raquel Sales Gil +3 more
openaire +5 more sources
Mutant lamins cause nuclear envelope rupture and DNA damage in skeletal muscle cells
bioRxiv, 2018 Mutations in the LMNA gene, which encodes the nuclear envelope (NE) proteins lamins A/C, cause Emery–Dreifuss muscular dystrophy, congenital muscular dystrophy and other diseases collectively known as laminopathies.
Ashley J. Earle +9 more
semanticscholar +1 more source
The Arabidopsis Nuclear Pore and Nuclear Envelope [PDF]
The Arabidopsis Book, 2010 The nuclear envelope is a double membrane structure that separates the eukaryotic cytoplasm from the nucleoplasm. The nuclear pores embedded in the nuclear envelope are the sole gateways for macromolecular trafficking in and out of the nucleus. The nuclear pore complexes assembled at the nuclear pores are large protein conglomerates composed of ...
Jelena Brkljacic, Iris Meier
openaire +2 more sources
Nuclear Envelope Permeability Barrier as a Fast‐Response Intracellular Mechanostat
Advanced Science, 2019 The nuclear envelope is an undisputed component of the intracellular mechanotransduction cascades which collect, process, and respond to mechanical stimuli from the environment.
Victor Shahin +3 more
doaj +1 more source
Dynamics and Structure-Function Relationships of the Lamin B Receptor (LBR). [PDF]
PLoS ONE, 2017 The lamin B receptor (LBR) is a multi-spanning membrane protein of the inner nuclear membrane that is often employed as a "reporter" of nuclear envelope dynamics. We show here that the diffusional mobility of full-length LBR exhibits significant regional
Ioannis Giannios +2 more
doaj +1 more source
Proceedings of the National Academy of Sciences of the United States of America, 2019 Significance Neutrophils are white blood cells specialized as the first line of host defense in the immune system. One way they protect organisms is through NETosis, in which they expel their DNA to form a web-like trap that ensnares pathogens and ...
H. Thiam +8 more
semanticscholar +1 more source
Nuclear lipid droplets identified by electron microscopy of serial sections. [PDF]
, 2013 International audienceBACKGROUND: Recent studies have suggested that nuclear lipid droplets (LDs) are organized into domains similar to those of cytoplasmic LDs.
Roingeard, Philippe, Uzbekov, Rustem
core +3 more sources
Cellular and Molecular Life Sciences, 2001 This review summarizes our present knowledge about the composition and function of the plant nuclear envelope. Compared with animals or yeast, our molecular knowledge of the nuclear envelope in higher plants is in its infancy. However, there are fundamental differences between plants and animals in the structure and function of the nuclear envelope ...
Iris Meier
openalex +4 more sources