Results 31 to 40 of about 149,980 (205)

Both emerin and lamin C depend on lamin A for localization at the nuclear envelope [PDF]

, 2001
Physical interactions between lamins and emerin were investigated by co-immunoprecipitation of in vitro translated proteins. Emerin interacted with in vitro translated lamins A, B1 and C in co-immunprecipitation reactions.
Whitfield, WGF, Ramaekers, FCS, Hutchison, CJ, Bridger, J.M., Vaughan, OA, Bridger, JM, Ramaekers, F.C.S., Hutchison, C.J., Broers, JL, Raemakers, FC, Alvarez-Reyes, M, Alvarez-Reyes, M., Whitfield, W.G.F., Vaughan, A, Wehnert, M, Broers, JLV, Vaughan, O.A., Morris, G.E., Morris, GE, Wehnert, M., Broers, J.L.V.   +20 more
core   +1 more source

Nuclear envelope remnants: fluid membranes enriched in sterols and polyphosphoinositides.

PLoS ONE, 2009
BackgroundThe cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell.
Marie Garnier-Lhomme, Richard D Byrne, Tina M C Hobday, Stephen Gschmeissner, Rudiger Woscholski, Dominic L Poccia, Erick J Dufourc, Banafshé Larijani   +7 more
doaj   +1 more source

Energy- and temperature-dependent transport of integral proteins to the inner nuclear membrane via the nuclear pore [PDF]

, 2004
Resident integral proteins of the inner nuclear membrane (INM) are synthesized as membrane-integrated proteins on the peripheral endoplasmic reticulum (ER) and are transported to the INM throughout interphase using an unknown trafficking mechanism.
Gerace, Larry, Nishimoto, Takeharu, Schirmer, Eric C, Eric C. Schirmer, Ohba, Tomoyuki, Tomoyuki Ohba, Takeharu Nishimoto, Larry Gerace   +7 more
core   +1 more source

The role of the nuclear envelope in the regulation of chromatin dynamics during cell division [PDF]

, 2020
The nuclear envelope delineates the eukaryotic cell nucleus. The membrane system of the nuclear envelope consists of an outer nuclear membrane and an inner nuclear membrane separated by a perinuclear space.
Pradillo Orellana, Mónica, Fernández Jiménez, Nadia   +1 more
core   +1 more source

NUP-1 is a large coiled-coil nucleoskeletal protein in Trypanosomes with lamin-like functions [PDF]

, 2012
A unifying feature of eukaryotic nuclear organization is genome segregation into transcriptionally active euchromatin and transcriptionally repressed heterochromatin.
Wan, Yakun, Kelly N DuBois, J. David Barry, Rout, Michael P., Alsford, S., Holden, Jennifer M., DuBois, K.N., Rout Michael P., Rout, Michael P, Jean-Mathieu Bart (176093), Field, Mark C, DuBois, Kelly N., Alsford Sam, Aitchison, J.D., Buisson, J., Mathieu Bart, Barry, J. David, Navarro Miguel, Horn David, Field, Mark C., Field Mark C., Misteli, T., Ratushny, Alexander V., Swiderski, Michal, Horn, David, Rout, M.P., Mark C. Field (129657), David Horn (24969), Jennifer M. Holden, Bastin Philippe, DuBois, Kelly N, Alexander V. Ratushny (102304), Barry, J.D., Barry, J David, Holden Jennifer M., Miguel Navarro, Michal Swiderski (176090), John D. Aitchison (102330), Bart, J., Johanna Buisson, J David Barry, John D. Aitchison, Holden, Jennifer M, Bastin, Philippe, DuBois Kelly N., Navarro, M., Barry J. David, Philippe Bastin (25974), Michael P. Rout (25373), Aitchison John D., Jennifer M Holden, Ratushny, A.V., Kelly N. Dubois, Buisson Johanna, Field, M.C., Alsford, Sam, Philippe Bastin, Swiderski, M., Wan, Y., Ratushny, Alexander V, Bastin, P., Kelly N. DuBois (176072), Horn, D., Michael P Rout, Aitchison, John D, Jean-Mathieu Bart, Buisson, Johanna, Bart, Jean-Mathieu, Sam Alsford (24967), Yakun Wan, David Horn, Mark C. Field, J. David Barry (60385), Navarro, Miguel, Aitchison, John D., Jennifer M. Holden (176080), Miguel Navarro (176103), Sam Alsford, Bart Jean-Mathieu, Ratushny Alexander V., Michael P. Rout, Yakun Wan (176097), Wan Yakun, Horn, David; id_orcid, Holden, J.M., Swiderski Michal, John D Aitchison, Mark C Field, Johanna Buisson (176084), Michal Swiderski, Er V. Ratushny, Alexander V Ratushny   +91 more
core   +1 more source

Dynamic rearrangement of nucleoporins during fungal "open" mitosis [PDF]

, 2008
Mitosis in animals starts with the disassembly of the nuclear pore complexes and the breakdown of the nuclear envelope. In contrast to many fungi, the corn smut fungus Ustilago maydis also removes the nuclear envelope.
Theisen, Ulrike, Steinberg, Gero, Straube, Anne   +2 more
core   +1 more source

Nuclear pores safeguard the integrity of the nuclear envelope. [PDF]

Nat Cell Biol
Nuclear pore complexes (NPCs) constitute giant channels within the nuclear envelope that mediate nucleocytoplasmic exchange. NPC diameter is thought to be regulated by nuclear envelope tension, but how such diameter changes are physiologically linked to ...
Taniguchi R, Orniacki C, Kreysing JP, Zila V, Zimmerli CE, Böhm S, Turoňová B, Kräusslich HG, Doye V, Beck M.   +9 more
europepmc   +3 more sources

Signal Transduction across the Nuclear Envelope: Role of the LINC Complex in Bidirectional Signaling

Cells, 2019
The primary functions of the nuclear envelope are to isolate the nucleoplasm and its contents from the cytoplasm as well as maintain the spatial and structural integrity of the nucleus.
Miki Hieda
doaj   +1 more source

Protein phosphatases at the nuclear envelope [PDF]

Biochemical Society Transactions, 2018
The nuclear envelope (NE) is a unique topological structure formed by lipid membranes (Inner and Outer Membrane: IM and OM) interrupted by open channels (Nuclear Pore complexes). Besides its well-established structural role in providing a physical separation between the genome and the cytoplasm and regulating the exchanges between the two cellular ...
Raquel Sales Gil, Ines J. de Castro, Jerusalem Berihun, Paola Vagnarelli   +3 more
openaire   +3 more sources

Nuclear Envelope Regulation of Oncogenic Processes: Roles in Pancreatic Cancer

Epigenomes, 2018
Pancreatic cancer is an aggressive and intractable malignancy with high mortality. This is due in part to a high resistance to chemotherapeutics and radiation treatment conferred by diverse regulatory mechanisms.
Claudia C. Preston, Randolph S. Faustino   +1 more
doaj   +1 more source