Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication [PDF]
, 1994 The major residual structure that remains associated with the nuclear envelope following extraction of isolated nuclei or oocyte germinal vesicles with non-ionic detergents, nucleases and high salt is the lamina (Fawcett, 1966; Aaronson and Blobel ...
Hutchison, CJ +3 more
core +6 more sources
Both emerin and lamin C depend on lamin A for localization at the nuclear envelope [PDF]
, 2001 Physical interactions between lamins and emerin were investigated by co-immunoprecipitation of in vitro translated proteins. Emerin interacted with in vitro translated lamins A, B1 and C in co-immunprecipitation reactions.
Whitfield, WGF +8 more
core +8 more sources
The nuclear envelope in higher plant mitosis and meiosis [PDF]
Nucleus, 2019 Mitosis and meiosis in higher plants involve significant reconfiguration of the nuclear envelope and the proteins that interact with it. The dynamic series of events involves a range of interactions, movement, breakdown, and reformation of this complex ...
Monica Pradillo +2 more
doaj +2 more sources
Discovery and restoration of Aberrant Nuclear structure and Genome behaviour in breast cancer cells [PDF]
, 2013 This thesis was submitted for the degree of Doctor of Philosophy and awarded by Brunel University.The eukaryotic interphase nucleus is well organised and the genome positioned non-randomly.
Hassan Ahmed, Mai
core +7 more sources
Cell migration in dense microenvironments
Comptes Rendus Biologies, 2023 The nucleus has been viewed as a passenger during cell migration that functions merely to protect the genome. However, increasing evidence shows that the nucleus is an active organelle, constantly sensing the surrounding environment and translating ...
de Freitas Nader, Guilherme Pedreira +1 more
doaj +1 more source
High-Throughput Mechanical Rupture of Nuclear Envelope and the Intracellular Dynamics of Massive Wound Repair. [PDF]
Adv Sci (Weinh)A microfluidic device with monolithically integrated nanostructures enables high‐throughput wounding of the cell membrane and nuclear envelope. The spatial distribution of charged multivesicular body protein 4B (CHMP4B) within the cell is mapped before and after wounding, showing involvement in repair of both the cell membrane and nuclear envelope ...
Fajrial AK +5 more
europepmc +2 more sources
Interplay of the nuclear envelope with chromatin in physiology and pathology
Nucleus, 2020 The nuclear envelope compartmentalizes chromatin in eukaryotic cells. The main nuclear envelope components are lamins that associate with a panoply of factors, including the LEM domain proteins.
Romina Burla +5 more
doaj +1 more source
Nuclear envelope budding and its cellular functions
Nucleus, 2023 The nuclear pore complex (NPC) has long been assumed to be the sole route across the nuclear envelope, and under normal homeostatic conditions it is indeed the main mechanism of nucleo-cytoplasmic transport.
Katharina S. Keuenhof +6 more
doaj +1 more source
The Plant Nuclear Envelope and Its Role in Gene Transcription
Frontiers in Plant Science, 2021 Chromosomes are dynamic entities in the eukaryotic nucleus. During cell development and in response to biotic and abiotic change, individual sections as well as entire chromosomes re-organise and reposition within the nuclear space.
Jade Bishop +3 more
doaj +1 more source
Specific nuclear envelope transmembrane proteins can promote the location of chromosomes to and from the nuclear periphery [PDF]
, 2013 BACKGROUND: Different cell types have distinctive patterns of chromosome positioning in the nucleus. Although ectopic affinity-tethering of specific loci can be used to relocate chromosomes to the nuclear periphery, endogenous nuclear envelope proteins ...
Vassiliki Lazou +23 more
core +1 more source