Results 21 to 30 of about 1,755,500 (237)
Organellar proteomics: the prizes and pitfalls of opening the nuclear envelope [PDF]
, 2002 Proteomic studies have the potential to comprehensively define the composition of organelles but are limited by the organellar cross-contamination that arises during subcellular fractionation.
Gerace, Larry, Schirmer, Eric C
core +1 more source
eLife, 2020 The switch from centrosomal microtubule-organizing centers (MTOCs) to non-centrosomal MTOCs during differentiation is poorly understood. Here, we identify AKAP6 as key component of the nuclear envelope MTOC.
Silvia Vergarajauregui +10 more
doaj +1 more source
Cells, 2023 Regulator of TElomere Length Helicase 1 (RTEL1) is a helicase required for telomere maintenance and genome replication and repair. RTEL1 has been previously shown to participate in the nuclear export of small nuclear RNAs.
Michael Schertzer +5 more
doaj +1 more source
The nuclear envelopathies and human diseases
Journal of Biomedical Science, 2009 The nuclear envelope (NE) consists of two membrane layers that segregate the nuclear from the cytoplasmic contents. Recent progress in our understanding of nuclear-lamina associated diseases has revealed intriguing connections between the envelope ...
Jeang Kuan-Teh, Chen Zi-Jie, Chi Ya-Hui
doaj +1 more source
Cell Communication and Signaling, 2023 Fibroblast growth factor receptor 1 (FGFR1) is a heavily N-glycosylated cell surface receptor tyrosine kinase that transmits signals across the plasma membrane, in response to fibroblast growth factors (FGFs).
Paulina Gregorczyk +8 more
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Nuclear envelope remnants: fluid membranes enriched in sterols and polyphosphoinositides.
PLoS ONE, 2009 BackgroundThe cytoplasm of eukaryotic cells is a highly dynamic compartment where membranes readily undergo fission and fusion to reorganize the cytoplasmic architecture, and to import, export and transport various cargos within the cell.
Marie Garnier-Lhomme +7 more
doaj +1 more source
Involvement of the lamin rod domain in heterotypic lamin interactions important for nuclear organization [PDF]
, 2001 The nuclear lamina is a meshwork of intermediate-type filament proteins (lamins) that lines the inner nuclear membrane. The lamina is proposed to be an important determinant of nuclear structure, but there has been little direct testing of this idea.
Tinglu Guan +5 more
core +1 more source
Signal Transduction across the Nuclear Envelope: Role of the LINC Complex in Bidirectional Signaling
Cells, 2019 The primary functions of the nuclear envelope are to isolate the nucleoplasm and its contents from the cytoplasm as well as maintain the spatial and structural integrity of the nucleus.
Miki Hieda
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Repo-Man coordinates chromosomal reorganization with nuclear envelope reassembly during mitotic exit [PDF]
, 2011 This article is available open access under a Creative Commons license (http://creativecommons.org/licenses/by/3.0/). Copyright @ 2011 Elsevier Inc.Repo-Man targets protein phosphatase 1 γ (PP1γ) to chromatin at anaphase onset and regulates chromosome ...
Vagnarelli, Paola +31 more
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Nuclear Envelope Regulation of Oncogenic Processes: Roles in Pancreatic Cancer
Epigenomes, 2018 Pancreatic cancer is an aggressive and intractable malignancy with high mortality. This is due in part to a high resistance to chemotherapeutics and radiation treatment conferred by diverse regulatory mechanisms.
Claudia C. Preston +1 more
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