Results 41 to 50 of about 149,980 (205)

Ultradonut Topology of the Nuclear Envelope [PDF]

Biophysical Journal, 2016
Significance Lipid membranes exhibit a variety of morphologies tailored to perform specific functions of cells and their organelles. A unique lipid structure is the nuclear envelope which houses the genome and plays a vital role in genome organization and signaling pathways.
University of Houston, Houston, TX, USA ( host institution ), Torbati, Mehdi ( author ), Lele, Tanmay P. ( UF author ), Agrawal, Ashutosh ( author )   +3 more
openaire   +4 more sources

Nuclear Envelope Permeability Barrier as a Fast‐Response Intracellular Mechanostat

Advanced Science, 2019
The nuclear envelope is an undisputed component of the intracellular mechanotransduction cascades which collect, process, and respond to mechanical stimuli from the environment.
Victor Shahin, Ivan U. Kouzel, Gonzalo Rosso, Ivan Liashkovich   +3 more
doaj   +1 more source

Remodeling of the Nuclear Envelope and Lamina during Bovine Preimplantation Development and Its Functional Implications. [PDF]

PLoS ONE, 2015
The present study demonstrates a major remodeling of the nuclear envelope and its underlying lamina during bovine preimplantation development. Up to the onset of major embryonic genome activation (MGA) at the 8-cell stage nuclei showed a non-uniform ...
Jens Popken, Alexander Graf, Stefan Krebs, Helmut Blum, Volker J Schmid, Axel Strauss, Tuna Guengoer, Valeri Zakhartchenko, Eckhard Wolf, Thomas Cremer   +9 more
doaj   +1 more source

NDC1 : a crucial membrane-integral nucleoporin of metazoan nuclear pore complexes [PDF]

, 2006
POM121 and gp210 were, until this point, the only known membrane-integral nucleoporins (Nups) of vertebrates and, thus, the only candidate anchors for nuclear pore complexes (NPCs) within the nuclear membrane. In an accompanying study (Stavru et al.), we
Gorlich, D., Hülsmann, Bastian, Anne Spang, Cordes, V., Stavru, F., Hartmann, E., Dirk Görlich, Spang, Anne, Cordes, Volker, C., Volker C. Cordes, Hülsmann, B., Hulsmann, B. B., Bastian B. Hülsmann, Cordes, V. C., Hartmann, Enno, Fabrizia Stavru, Görlich, Dirk, Stavru, Fabrizia, Enno Hartmann, Spang, A., Cordes, Volker,   +20 more
core   +1 more source

Deformation of the nucleus by TGFβ1 via the remodeling of nuclear envelope and histone isoforms

Epigenetics & Chromatin, 2022
The cause of nuclear shape abnormalities which are often seen in pre-neoplastic and malignant tissues is not clear. In this study we report that deformation of the nucleus can be induced by TGFβ1 stimulation in several cell lines including Huh7.
Ya-Hui Chi, Wan-Ping Wang, Ming-Chun Hung, Gunn-Guang Liou, Jing-Ya Wang, Pen-Hsiu Grace Chao   +5 more
doaj   +1 more source

Exotic mitotic mechanisms [PDF]

, 2012
The emergence of eukaryotes around two billion years ago provided new challenges for the chromosome segregation machineries: the physical separation of multiple large and linear chromosomes from the microtubule-organizing centres by the nuclear envelope.
Drechsler, Hauke, McAinsh, Andrew D.
core   +1 more source

Nuclear envelope mechanobiology: linking the nuclear structure and function

Nucleus, 2021
The nucleus, central to cellular activity, relies on both direct mechanical input as well as its molecular transducers to sense external stimuli and respond by regulating intra-nuclear chromatin organization that determines cell function and fate.
Matthew Goelzer, Julianna Goelzer, Matthew L. Ferguson, Corey P. Neu, Gunes Uzer   +4 more
doaj   +1 more source

Characterization of the cellular functions of the nucleoporins Nup153 and Nup88 [PDF]

, 2010
Characterization of the Cellular Functions of the Nucleoporins Nup153 and Nup88 PhD Thesis, Yvonne Christine Lussi, 2010, University of Basel Nuclear pore complexes (NPCs) and nuclear lamins are major constituents of the nuclear envelope (NE) in ...
Lussi, Yvonne Christine
core   +1 more source

Viruses and the nuclear envelope

Current Opinion in Cell Biology, 2015
Viruses encounter and manipulate almost all aspects of cell structure and metabolism. The nuclear envelope (NE), with central roles in cell structure and genome function, acts and is usurped in diverse ways by different viruses. It can act as a physical barrier to infection that must be overcome, as a functional barrier that restricts infection by ...
Hennig, T, O'Hare, P
openaire   +4 more sources

Defining the core proteome of the chloroplast envelope membranes [PDF]

, 2013
High-throughput protein localization studies require multiple strategies. Mass spectrometric analysis of defined cellular fractions is one of the complementary approaches to a diverse array of cell biological methods. In recent years, the protein content
Bernd Müller, Enrico eSchleiff, Mirus, Oliver, Stefan Simm, Michael Karas, Papasotiriou, Dimitrios, Papasotiriou, Dimitrios G., Dimitrios G. Papasotiriou, Schleiff, Enrico, Oliver Mirus, Bernd eMüller, Maik eSommer, Matthias S. Leisegang, Sommer, Maik Sascha, Maik S. Sommer, Dimitri ePapasotiriou, Stefan eSimm, Leisegang, Matthias S., Simm, Stefan, Mohamed eIbrahim, Oliver eMirus, Schorge, Tobias, Enrico Schleiff, Ibrahim, Mohamed, Matthias eLeisegang, Mohamed Ibrahim, Michael eKaras, Tobias Schorge, Müller, Bernd, Sommer, Maik S., Leisegang, Matthias, Tobias eSchorge, Karas, Michael   +32 more
core   +1 more source