The protein import apparatus of chloroplasts [PDF]
, 1993 Routing of cytosolically synthesized precursor proteins into chloroplasts is a specific process which involves a multitude of soluble and membrane components.
Soll, Jürgen +3 more
core +1 more source
Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression [PDF]
, 2007 Copyright @ 2007 The Rockefeller UniversityRadial organization of nuclei with peripheral gene-poor chromosomes and central gene-rich chromosomes is common and could depend on the nuclear boundary as a scaffold or position marker. To test this, we studied
Vaux, DJ +11 more
core +1 more source
Immunocytochemistry of nuclear domains and Emery-Dreifuss muscular dystrophy pathophysiology
European Journal of Histochemistry, 2009 The present review summarizes recent cytochemical findings on the functional organization of the nuclear domains, with a particular emphasis on the relation between nuclear envelope- associated proteins and chromatin.
NM Maraldi +8 more
doaj +1 more source
The role of emerin and LEM domain proteins in nuclear envelope assembly and cytoskeleton organisation [PDF]
, 2005 The nuclear envelope (NE) plays a fundamental role in the cell by separating nuclear from cytoplasmic activities, and mutations in NE proteins have been associated with a diverse array of diseases.
Saipingidou, Georgia +1 more
core
LINCing Senescence and Nuclear Envelope Changes
Cells, 2022 The nuclear envelope (NE) has emerged as a nexus for cellular organization, signaling, and survival. Beyond its role as a barrier to separate the nucleoplasm from the cytoplasm, the NE’s role in supporting and maintaining a myriad of other functions has ...
Bakhita R. M. Meqbel +4 more
doaj +1 more source
Nuclear Envelope: Nuclear Pore Complexity [PDF]
Current Biology, 2005 A new study shows that the filamentous fungus, Aspergillus nidulans, which has a closed mitosis, does not maintain a continuous permeability barrier during mitosis. This work challenges current views of the differences between closed and open mitosis and has implications for understanding mitotic specific changes in the nuclear pore complex and Ran ...
openaire +2 more sources
Weaving a pattern from disparate threads: lamin function in nuclear assembly and DNA replication [PDF]
, 1994 The major residual structure that remains associated with the nuclear envelope following extraction of isolated nuclei or oocyte germinal vesicles with non-ionic detergents, nucleases and high salt is the lamina (Fawcett, 1966; Aaronson and Blobel ...
Hutchison, CJ +3 more
core
Parvoviruses cause nuclear envelope breakdown by activating key enzymes of mitosis. [PDF]
PLoS Pathogens, 2013 Disassembly of the nuclear lamina is essential in mitosis and apoptosis requiring multiple coordinated enzymatic activities in nucleus and cytoplasm. Activation and coordination of the different activities is poorly understood and moreover complicated as
Manvi Porwal +10 more
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Human Telomeres Are Tethered to the Nuclear Envelope during Postmitotic Nuclear Assembly
Cell Reports, 2012 Telomeres are essential for nuclear organization in yeast and during meiosis in mice. Exploring telomere dynamics in living human cells by advanced time-lapse confocal microscopy allowed us to evaluate the spatial distribution of telomeres within the ...
Laure Crabbe +4 more
doaj +1 more source
The SUN protein Mps3 is required for spindle pole body insertion into the nuclear membrane and nuclear envelope homeostasis. [PDF]
PLoS Genetics, 2011 The budding yeast spindle pole body (SPB) is anchored in the nuclear envelope so that it can simultaneously nucleate both nuclear and cytoplasmic microtubules. During SPB duplication, the newly formed SPB is inserted into the nuclear membrane.
Jennifer M Friederichs +9 more
doaj +1 more source