Results 81 to 90 of about 2,595,567 (290)

Exploration of a Fast Pathway to Nuclear Fusion: Thermal Analysis and Cooling Design Considerations for the ARC Reactor

, 2020
Progress in technological fields such as high-temperature superconductors, additive manufacturing, and innovative materials has led to new scenarios and to a second generation of fusion reactor designs.
Zucchetti, Massimo, Whyte, Dennis G, Hartwig, Zachary Seth   +2 more
core   +1 more source

Modelling for JET Vertical Stabilization System [PDF]

, 2010
Nuclear fusion is, in a sense, the opposite of nuclear fission. Fission, which is a mature technology, produces energy through the splitting of heavy atoms like uranium in controlled chain reactions.
Bellizio, Teresa
core   +1 more source

Comparative study of surface modification of fluorinated and non-fluorinated polymers using SDBD air plasma

Scientific Reports
This study investigates the surface modification of Fluorinated Polytetrafluoroethylene PTFE and Non-Fluorinated polyethylene PE, two widely used polymers with inherent hydrophobicity and poor adhesion, using atmospheric air plasma generated by Surface ...
Soolmaz Jamali, Ameneh Kargarian
doaj   +1 more source

Targeting transcription factors associated with hemoglobinopathies: Lessons from successful interventions and implications for cancer

Molecular Oncology, EarlyView.
This review summarizes the transcription factors, repressive chromatin‐modifying complexes, and epigenetic mechanisms that control fetal hemoglobin repression. Notably, many regulators of γ‐globin silencing also function in transcriptional and epigenetic networks that drive cancer, highlighting opportunities to translate advances in hemoglobinopathy ...
Meigen Yu, Puspa Das, Xing Zhang, Xiaodong Cheng   +3 more
wiley   +1 more source

ADP‐ribosylation: An emerging regulator of the epigenome

Molecular Oncology, EarlyView.
ADP‐ribosylation has emerged as a dynamic epigenetic signaling mechanism that modifies histones and chromatin‐associated proteins. Through coordinated PARylation and MARylation, it integrates with other histone modifications to regulate chromatin structure, transcription factor activity, and gene expression, influencing genome function and disease ...
Cristel V. Camacho, Chenqian Liu, W. Lee Kraus   +2 more
wiley   +1 more source

Radiative type-III ELMy H-mode in all-tungsten ASDEX Upgrade [PDF]

, 2012
The type-III ELMy H-mode might be the solution for an integrated ITER operation scenario fulfilling the fusion power amplification factor (output fusion power to input heating power) of Q = 10 with simultaneous acceptable steady-state and transient power
Rooij, van, G.J.; id_orcid, Herrmann, A., G. J. van Rooij, Potzel, S., Fischer, R., Rooij, van, G.J., van Rooij, G.J., Team, ASDEXUpgrade, Neu, R., Eich, T., Rooij, G. V. van, Zielinski, J.J., Zielinski, J. J., ASDEX Upgrade Team, Rooij, G., Zielinski, J., Rapp, J., Kallenbach, A.   +17 more
core   +1 more source

Paclitaxel induces NM2‐dependent cellular contraction through GEF‐H1 dissociation from microtubules and RhoA/ROCK activation in cancer cells

Molecular Oncology, EarlyView.
Taxanes are widely used chemotherapeutics whose effects on cellular mechanics remain poorly understood. We show that paclitaxel induces rapid cellular contraction by promoting GEF‐H1 dissociation from microtubules and non‐muscle myosin II activation through RhoA/ROCK.
Gloria Asensio‐Juárez, Rafael Pérez‐Díaz, Hugo Ramos‐Solano, Marina Garrido‐Casado, Vanessa C. Talayero, Miguel Vicente‐Manzanares   +5 more
wiley   +1 more source

An Archival Study on the Fusion Researches in Japan from 1965 to 1986 An Interview with Sekiguchi Tadashi [PDF]

, 2001
We here report an archival study undertaken by the method of an interview with Sekiguchi Tadashi, Professor Emeritus at the University of Tokyo. The theme covers the circumstances of the fusion research during the period (1965-1976) when fusion project ...
KAWAKAMI, Ichiro, KIMURA, Kazue, UEMATSU, Eisui, TAKAIWA, Yoshinobu, NISIO, Shigeko, OBAYASHI, Haruo, TAKEDA, Tatsuoki, NAMBA, Chusei, NISHIO, Shigeko, FUJITA, Junji, WAKATANI, Masahiro, TERASHIMA, Yoshinosuke   +11 more
core  

Mutant p53R273H disrupts PDPK1 homodimerization and contributes to PDPK1 activation

Molecular Oncology, EarlyView.
How mutant p53R273H drives AKT signaling is unclear. We show that p53R273H, but not wild‐type, directly binds PDPK1 via a mutation‐dependent conformational change. This interaction disrupts inhibitory PDPK1 homodimerization and enhances AKT phosphorylation.
Mei Chee Lim, Alvin Kunyao Guo, Yoko Itahana, Srinivasaraghavan Kannan, Valerie Goh, Mingmin Ong, Terina Yan Wen Tay, Weiying Ye, Sabhashina Radha Krishnan, Jun Nishiyama, Chandra S Verma, Koji Itahana   +11 more
wiley   +1 more source

Implementation of neoclassical effects in momentum transport analysis at LHD [PDF]

, 2017
Plasma rotation plays an important role in the suppression of turbulence, leading to an increase in energy and particle confinement. Significant rotation also leads to a stabilisation of the resistive wall mode.
BECKERS, Jasper, Yokoyama, Masayuki, Jaspers, RJE Roger, Ida, K., Yokoyama, M., Emoto, M, Ryosuke SEKI, Yoshinuma, M., IDA, Katsumi, Masayuki YOKOYAMA, Seki, Ryosuke, Masahiko EMOTO, Jasper BECKERS, Beckers, J.P., Emoto, M., YOKOYAMA, Masayuki, Roger JASPERS, Jaspers, R.J.E., EMOTO, Masahiko, Mikirou YOSHINUMA, Seki, R., Katsumi IDA, Ida, K, SEKI, Ryosuke, Yoshinuma, M, Beckers, JP, YOSHINUMA, Mikirou, JASPERS, Roger   +27 more
core   +1 more source