Results 11 to 20 of about 1,802,430 (358)
Nuclear neighborhoods and gene expression [PDF]
Current Opinion in Genetics & Development, 2009 The eukaryotic nucleus is a highly compartmentalized and dynamic environment. Chromosome territories are arranged nonrandomly within the nucleus and numerous studies have indicated that a gene's position in the nucleus can impact its transcriptional activity.
Megan S. Bodnar +3 more
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AN UNSTABLE NUCLEAR GENE IN PHYCOMYCES [PDF]
Genetics, 1979 ABSTRACT A gentic instability in Phycomyces is described that appears to be associated with a single nuclear gene, dar. The wild type is able to take up riboflavin and its toxic analogue, deaza-riboflavin, from nanomolar concentrations in the medium.
Max Delbrück, T. Ootaki
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The evolution of plant nuclear genes [PDF]
Proceedings of the National Academy of Sciences, 1997 We analyze the evolutionary dynamics of three of the best-studied plant nuclear multigene families. The data analyzed derive from the genes that encode the small subunit of ribulose-1,5-bisphosphate carboxylase ( rbc S), the gene family that encodes the enzyme chalcone synthase ( Chs ...
Mary L. Durbin +2 more
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Gene silencing at the nuclear periphery [PDF]
The FEBS Journal, 2007 The nuclear envelope (NE) is composed of inner and outer nuclear membranes (INM and ONM, respectively), nuclear pore complexes and an underlying mesh like supportive structure – the lamina. It has long been known that heterochromatin clusters at the nuclear periphery adjacent to the nuclear lamina, hinting that proteins of the lamina may participate in
Gideon Rechavi +3 more
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Nuclear architecture and gene regulation
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008 The spatial organization of eukaryotic genomes in the cell nucleus is linked to their transcriptional regulation. In mammals, on which this review will focus, transcription-related chromatin positioning is regulated at the level of chromosomal sub-domains and individual genes. Most of the chromatin remains stably positioned during interphase.
Elena Fedorova, Daniele Zink
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Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression
Nucleus, 2023 Eukaryotic cells organize their genome within the nucleus with a double-layered membrane structure termed the nuclear envelope (NE) as the physical barrier.
Yu Tang
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Identifying gene locus associations with promyelocytic leukemia nuclear bodies using immuno-TRAP. [PDF]
, 2013 Important insights into nuclear function would arise if gene loci physically interacting with particular subnuclear domains could be readily identified.
Ahmed, Kashif +4 more
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Frontiers in Plant Science, 2017 Chloroplast DNA (cpDNA) is frequently used for species demography, evolution, and species discrimination of plants. However, the lack of efficient and universal markers often brings particular challenges for genetic studies across different plant groups.
Jia Yang +6 more
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Scientific Reports, 2023 The prognosis of relapsed/refractory (R/R) neuroblastoma (NB) is dismal, calling for new therapeutic strategies. Venetoclax (VEN) is a highly selective, potent, orally bioavailable, BCL-2 inhibitor small-molecule that showed a synergistic effect with ...
Maria Antonietta De Ioris +14 more
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Inter- and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys [PDF]
, 2005 Recently it has been shown that the gene-density correlated radial distribution of human 18 and 19 homologous chromosome territories (CTs) is conserved in higher primates in spite of chromosomal rearrangements that occurred during evolution.
ISHIDA Takafumi +5 more
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