Results 11 to 20 of about 9,439,218 (381)
MicroRNA in Control of Gene Expression: An Overview of Nuclear Functions [PDF]
International Journal of Molecular Sciences, 2016 The finding that small non-coding RNAs (ncRNAs) are able to control gene expression in a sequence specific manner has had a massive impact on biology. Recent improvements in high throughput sequencing and computational prediction methods have allowed the
Caterina Catalanotto +2 more
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Nuclear neighborhoods and gene expression [PDF]
Current Opinion in Genetics & Development, 2009 The eukaryotic nucleus is a highly compartmentalized and dynamic environment. Chromosome territories are arranged nonrandomly within the nucleus and numerous studies have indicated that a gene's position in the nucleus can impact its transcriptional activity.
Megan S. Bodnar +3 more
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AN UNSTABLE NUCLEAR GENE IN PHYCOMYCES [PDF]
Genetics, 1979 ABSTRACT A gentic instability in Phycomyces is described that appears to be associated with a single nuclear gene, dar. The wild type is able to take up riboflavin and its toxic analogue, deaza-riboflavin, from nanomolar concentrations in the medium.
Max Delbrück, T. Ootaki
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The evolution of plant nuclear genes [PDF]
Proceedings of the National Academy of Sciences, 1997 We analyze the evolutionary dynamics of three of the best-studied plant nuclear multigene families. The data analyzed derive from the genes that encode the small subunit of ribulose-1,5-bisphosphate carboxylase ( rbc S), the gene family that encodes the enzyme chalcone synthase ( Chs ...
Mary L. Durbin +2 more
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Cancer Imaging, 2023 Background Chimeric antigen receptor T-cell therapy (CART) prolongs survival for patients with refractory or relapsed lymphoma. Discrepancies among different response criteria for lymphoma under CART were recently shown.
Michael Winkelmann +12 more
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Gene silencing at the nuclear periphery [PDF]
The FEBS Journal, 2007 The nuclear envelope (NE) is composed of inner and outer nuclear membranes (INM and ONM, respectively), nuclear pore complexes and an underlying mesh like supportive structure – the lamina. It has long been known that heterochromatin clusters at the nuclear periphery adjacent to the nuclear lamina, hinting that proteins of the lamina may participate in
Gideon Rechavi +3 more
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Journal of Education, Health and Sport, 2017 The development of new research techniques, especially molecular ones, creates hopes for improved treatment efficacy and a better prognosis in lung cancer.
Ewelina Wędrowska +7 more
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Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity [PDF]
, 2013 There are hints of an altered mitochondrial function in obesity. Nuclear-encoded genes are relevant for mitochondrial function (3 gene sets of known relevant pathways: (1) 16 nuclear regulators of mitochondrial genes, (2) 91 genes for oxidative ...
A Hinney +48 more
core +3 more sources
Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression
Nucleus, 2023 Eukaryotic cells organize their genome within the nucleus with a double-layered membrane structure termed the nuclear envelope (NE) as the physical barrier.
Yu Tang
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Nuclear architecture and gene regulation
Biochimica et Biophysica Acta (BBA) - Molecular Cell Research, 2008 The spatial organization of eukaryotic genomes in the cell nucleus is linked to their transcriptional regulation. In mammals, on which this review will focus, transcription-related chromatin positioning is regulated at the level of chromosomal sub-domains and individual genes. Most of the chromatin remains stably positioned during interphase.
Elena Fedorova, Daniele Zink
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