Chloroplast DNA (cpDNA) is frequently used for species demography, evolution, and species discrimination of plants. However, the lack of efficient and universal markers often brings particular challenges for genetic studies across different plant groups.
Jia Yang +6 more
doaj +1 more source
Gene set of nuclear-encoded mitochondrial regulators is enriched for common inherited variation in obesity [PDF]
There are hints of an altered mitochondrial function in obesity. Nuclear-encoded genes are relevant for mitochondrial function (3 gene sets of known relevant pathways: (1) 16 nuclear regulators of mitochondrial genes, (2) 91 genes for oxidative ...
A Hinney +48 more
core +3 more sources
Identifying gene locus associations with promyelocytic leukemia nuclear bodies using immuno-TRAP. [PDF]
Important insights into nuclear function would arise if gene loci physically interacting with particular subnuclear domains could be readily identified.
Ahmed, Kashif +4 more
core +2 more sources
New insights on early evolution of spiny-rayed fishes (Teleostei: Acanthomorpha)
The Acanthomorpha is the largest group of teleost fishes with about one third of extant vertebrate species. In the course of its evolution this lineage experienced several episodes of radiation, leading to a large number of descendant lineages differing ...
Wei-Jen eChen +6 more
doaj +1 more source
Plant nuclear envelope as a hub connecting genome organization with regulation of gene expression
Eukaryotic cells organize their genome within the nucleus with a double-layered membrane structure termed the nuclear envelope (NE) as the physical barrier.
Yu Tang
doaj +1 more source
Nuclear Photosynthetic Gene Expression Is Synergistically Modulated by Rates of Protein Synthesis in Chloroplasts and Mitochondria [PDF]
Arabidopsis thaliana mutants prors1-1 and -2 were identified on the basis of a decrease in effective photosystem II quantum yield. Mutations were localized to the 5'-untranslated region of the nuclear gene PROLYL-tRNA SYNTHETASE1 (PRORS1), which acts in ...
Bhushan, Shashi +7 more
core +2 more sources
Inter- and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys [PDF]
Recently it has been shown that the gene-density correlated radial distribution of human 18 and 19 homologous chromosome territories (CTs) is conserved in higher primates in spite of chromosomal rearrangements that occurred during evolution.
ISHIDA Takafumi +5 more
core +1 more source
Nuclear architecture and gene regulation
The spatial organization of eukaryotic genomes in the cell nucleus is linked to their transcriptional regulation. In mammals, on which this review will focus, transcription-related chromatin positioning is regulated at the level of chromosomal sub-domains and individual genes. Most of the chromatin remains stably positioned during interphase.
Fedorova, Elena, Zink, Daniele
openaire +2 more sources
The prognosis of relapsed/refractory (R/R) neuroblastoma (NB) is dismal, calling for new therapeutic strategies. Venetoclax (VEN) is a highly selective, potent, orally bioavailable, BCL-2 inhibitor small-molecule that showed a synergistic effect with ...
Maria Antonietta De Ioris +14 more
doaj +1 more source
Radiogenomics study to predict the nuclear grade of renal clear cell carcinoma
Purpose: To develop models based on radiomics and genomics for predicting the histopathologic nuclear grade with localized clear cell renal cell carcinoma (ccRCC) and to assess whether macro-radiomics models can predict the microscopic pathological ...
Xuan-ming He +5 more
doaj +1 more source

