Results 251 to 260 of about 1,892,385 (358)

Study of the Significance of Long Noncoding RNAs: Taurine-upregulated Gene-1, Urothelial Carcinoma-associated-1, Nuclear Paraspeckle Assembly Transcript-1, and Metastasis-associated Lung Adenocarcinoma Transcript-1 in Multiple Myeloma

Reham Abo Elwafa, Magdy Elbordiny, Ashraf Hussein Alghandour, Hala Sultan, Maha Gammal, Rahma Magdy, M. El-Shazly Samy, Ahmed Abd Elrahman, Marwa Gamaleldin   +8 more
openalex   +1 more source

Assessment of the Degree of Immunosuppression Measured by Residual Expression of Genes Regulated by T-Cell Nuclear Factor (NFAT-RGE) in Lung Transplant Recipients [PDF]

M. Boada Pérez, Victoria Ruiz, Marta Erro, Piedad Ussetti, Silvia Rosado, Raquel Castejón, Martin Aguilar, Eva Revilla‐López, C. Bravo Masgoret, B. Saez Gimenez, Moises Zapata, Cristina Berastegui, Manuel López‐Meseguer, Yolanda Villena-Ortiz, J. Vima Bofarull, Vı́ctor Monforte, S. Gomez   +16 more
openalex   +1 more source

Cysteinyl leukotriene signaling through perinuclear CysLT1 receptors on vascular smooth muscle cells transduces nuclear calcium signaling and alterations of gene expression [PDF]

, 2012
Alison Eaton, Edit Nagy, Mathilde Pacault, Jérémy Fauconnier, Magnus Bäck   +4 more
openalex   +1 more source

dUTPase is essential in zebrafish development and possesses several single‐nucleotide variants with pronounced structural and functional consequences

FEBS Open Bio, EarlyView.
dUTPases are involved in balancing the appropriate nucleotide pools. We showed that dUTPase is essential for normal development in zebrafish. The different zebrafish genomes contain several single‐nucleotide variations (SNPs) of the dut gene. One of the dUTPase variants displayed drastically lower protein stability and catalytic efficiency as compared ...
Viktória Perey‐Simon, Angéla Békesi, Latifa Kazzazy, Jázmin Mihály, Máté Varga, Beáta G. Vértessy, Kinga Nyíri   +6 more
wiley   +1 more source

The Polycomb-group gene, extra sex combs, encodes a nuclear member of the WD-40 repeat family. [PDF]

, 1995
Thomas Gutjahr, Erich Frei, Charlotte Spicer, Stefan Baumgartner, Robert A. White, Markus Noll   +5 more
openalex   +1 more source

The role of lipid metabolism in neuronal senescence

FEBS Open Bio, EarlyView.
Disrupted lipid metabolism, through alterations in lipid species or lipid droplet accumulation, can drive neuronal senescence. However, lipid dyshomeostasis can also occur alongside neuronal senescence, further amplifying tissue damage. Delineating how lipid‐induced senescence emerges in neurons and glial cells, and how it contributes to ageing and ...
Dikaia Tsagkari, Eleftheria Panagiotidou, Nektarios Tavernarakis   +2 more
wiley   +1 more source

A nuclear factor induced by hypoxia via de novo protein synthesis binds to the human erythropoietin gene enhancer at a site required for transcriptional activation.

, 1992
Gregg L. Semenza, G.L. Wang
openalex   +2 more sources

Microglial dynamics and ferroptosis induction in human iPSC‐derived neuron–astrocyte–microglia tri‐cultures

FEBS Open Bio, EarlyView.
A tri‐culture of iPSC‐derived neurons, astrocytes, and microglia treated with ferroptosis inducers as an Induced ferroptosis model was characterized by scRNA‐seq, cell survival, and cytokine release assays. This analysis revealed diverse microglial transcriptomic changes, indicating that the system captures key aspects of the complex cellular ...
Hongmei Lisa Li, Hiroko Ohmiya, Sou Sakamoto, Masato Yugami, Akiko Oki, Makoto Furusawa, Yan Ling   +6 more
wiley   +1 more source