Results 31 to 40 of about 1,892,385 (358)
Mobile genetic elements – mechanism and consequences of transposition
Retrotransposons represent a significant part of the genome in eukaryote organisms. With DNA transposons, they belong to mobile genetic elements. There are two classes of transposons, DNA transposons and retrotransposons.
Mateusz Wędrowski +5 more
doaj +3 more sources
We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet.
Kimberly J. Dunham-Snary +9 more
doaj +1 more source
AN UNSTABLE NUCLEAR GENE IN PHYCOMYCES [PDF]
ABSTRACT A gentic instability in Phycomyces is described that appears to be associated with a single nuclear gene, dar. The wild type is able to take up riboflavin and its toxic analogue, deaza-riboflavin, from nanomolar concentrations in the medium.
M, Delbrück, T, Ootaki
openaire +2 more sources
The Role of Nuclear Bodies in Gene Expression and Disease
This review summarizes the current understanding of the role of nuclear bodies in regulating gene expression. The compartmentalization of cellular processes, such as ribosome biogenesis, RNA processing, cellular response to stress, transcription ...
Marie Morimoto, Cornelius F. Boerkoel
doaj +1 more source
Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]
Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean +5 more
core +1 more source
Nuclear miRNAs: gene regulation activities
MicroRNAs are small non-coding RNAs, which contribute to the regulation of many physiolog-ical and pathological processes. Conventionally, miRNAs perform their activity in the cyto-plasm, where they regulate gene expression by interacting in a sequence-specific manner with mature messenger RNAs.
Monia Billi +4 more
openaire +2 more sources
Nuclear positioning, gene activity, and cancer [PDF]
In the interphasic nucleus, chromosomes are non-randomly arranged within the nuclear space. Indeed, chromosomes are thought to be organised into "chromosome territories". The size of a chromosome territory is roughly determined by its DNA content, but is also influenced by other factors, such as their transcriptional status. Chromatin modifications and
Guasconi, Valentina +2 more
openaire +3 more sources
Background The nuclear transport machinery is involved in a well-known male meiotic drive system in Drosophila. Fast gene evolution and gene duplications have been major underlying mechanisms in the evolution of meiotic drive systems, and this might ...
Ayda Mirsalehi +3 more
doaj +1 more source
Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation. [PDF]
We have detected DNA binding activity for a synthetic oligonucleotide containing an Sp1 consensus sequence in nuclear extracts from human chondrocytes. Changes in the levels of Sp1 oligonucleotide binding activity were examined in nuclear extracts from ...
Dharmavaram, Rita M. +3 more
core +2 more sources
Introduction Papillary thyroid carcinoma (PTC) is the most common malignant lesion of the thyroid characterized by unique histological features like nuclear grooving, nuclear clearing, and intra-nuclear inclusions.
Basavaraj Rangalakshmi Ashwini +3 more
doaj +1 more source

