Results 31 to 40 of about 1,892,385 (358)

Mobile genetic elements – mechanism and consequences of transposition

open access: yesJournal of Education, Health and Sport, 2017
Retrotransposons represent a significant part of the genome in eukaryote organisms. With DNA transposons, they belong to mobile genetic elements. There are two classes of transposons, DNA transposons and retrotransposons.
Mateusz Wędrowski   +5 more
doaj   +3 more sources

Mitochondrial – nuclear genetic interaction modulates whole body metabolism, adiposity and gene expression in vivoResearch in context

open access: yesEBioMedicine, 2018
We hypothesized that changes in the mitochondrial DNA (mtDNA) would significantly influence whole body metabolism, adiposity and gene expression in response to diet.
Kimberly J. Dunham-Snary   +9 more
doaj   +1 more source

AN UNSTABLE NUCLEAR GENE IN PHYCOMYCES [PDF]

open access: yesGenetics, 1979
ABSTRACT A gentic instability in Phycomyces is described that appears to be associated with a single nuclear gene, dar. The wild type is able to take up riboflavin and its toxic analogue, deaza-riboflavin, from nanomolar concentrations in the medium.
M, Delbrück, T, Ootaki
openaire   +2 more sources

The Role of Nuclear Bodies in Gene Expression and Disease

open access: yesBiology, 2013
This review summarizes the current understanding of the role of nuclear bodies in regulating gene expression. The compartmentalization of cellular processes, such as ribosome biogenesis, RNA processing, cellular response to stress, transcription ...
Marie Morimoto, Cornelius F. Boerkoel
doaj   +1 more source

Cell biological mechanisms of activity-dependent synapse to nucleus translocation of CRTC1 in neurons. [PDF]

open access: yes, 2015
Previous studies have revealed a critical role for CREB-regulated transcriptional coactivator (CRTC1) in regulating neuronal gene expression during learning and memory. CRTC1 localizes to synapses but undergoes activity-dependent nuclear translocation to
Ch'ng, Toh Hean   +5 more
core   +1 more source

Nuclear miRNAs: gene regulation activities

open access: yesInternational Journal of Molecular Sciences
MicroRNAs are small non-coding RNAs, which contribute to the regulation of many physiolog-ical and pathological processes. Conventionally, miRNAs perform their activity in the cyto-plasm, where they regulate gene expression by interacting in a sequence-specific manner with mature messenger RNAs.
Monia Billi   +4 more
openaire   +2 more sources

Nuclear positioning, gene activity, and cancer [PDF]

open access: yesCancer Biology & Therapy, 2005
In the interphasic nucleus, chromosomes are non-randomly arranged within the nuclear space. Indeed, chromosomes are thought to be organised into "chromosome territories". The size of a chromosome territory is roughly determined by its DNA content, but is also influenced by other factors, such as their transcriptional status. Chromatin modifications and
Guasconi, Valentina   +2 more
openaire   +3 more sources

Nuclear transport genes recurrently duplicate by means of RNA intermediates in Drosophila but not in other insects

open access: yesBMC Genomics, 2021
Background The nuclear transport machinery is involved in a well-known male meiotic drive system in Drosophila. Fast gene evolution and gene duplications have been major underlying mechanisms in the evolution of meiotic drive systems, and this might ...
Ayda Mirsalehi   +3 more
doaj   +1 more source

Detection and characterization of Sp1 binding activity in human chondrocytes and its alterations during chondrocyte dedifferentiation. [PDF]

open access: yes, 1997
We have detected DNA binding activity for a synthetic oligonucleotide containing an Sp1 consensus sequence in nuclear extracts from human chondrocytes. Changes in the levels of Sp1 oligonucleotide binding activity were examined in nuclear extracts from ...
Dharmavaram, Rita M.   +3 more
core   +2 more sources

A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation

open access: yesThyroid Research, 2023
Introduction Papillary thyroid carcinoma (PTC) is the most common malignant lesion of the thyroid characterized by unique histological features like nuclear grooving, nuclear clearing, and intra-nuclear inclusions.
Basavaraj Rangalakshmi Ashwini   +3 more
doaj   +1 more source

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