Results 41 to 50 of about 9,439,218 (381)

Nuclear transport genes recurrently duplicate by means of RNA intermediates in Drosophila but not in other insects

open access: yesBMC Genomics, 2021
Background The nuclear transport machinery is involved in a well-known male meiotic drive system in Drosophila. Fast gene evolution and gene duplications have been major underlying mechanisms in the evolution of meiotic drive systems, and this might ...
Ayda Mirsalehi   +3 more
doaj   +1 more source

Strategies on the nuclear-targeted delivery of genes [PDF]

open access: yesJournal of Drug Targeting, 2013
To improve the nuclear-targeted delivery of non-viral vectors, extensive effort has been carried out on the development of smart vectors which could overcome multiple barriers. The nuclear envelope presents a major barrier to transgene delivery. Viruses are capable of crossing the nuclear envelope to efficiently deliver their genome into the nucleus ...
Yuanke Li   +3 more
openaire   +3 more sources

Inter- and intra-specific gene-density-correlated radial chromosome territory arrangements are conserved in Old World monkeys [PDF]

open access: yes, 2005
Recently it has been shown that the gene-density correlated radial distribution of human 18 and 19 homologous chromosome territories (CTs) is conserved in higher primates in spite of chromosomal rearrangements that occurred during evolution.
ISHIDA Takafumi   +5 more
core   +1 more source

A study to evaluate association of nuclear grooving in benign thyroid lesions with RET/PTC1 and RET/PTC3 gene translocation

open access: yesThyroid Research, 2023
Introduction Papillary thyroid carcinoma (PTC) is the most common malignant lesion of the thyroid characterized by unique histological features like nuclear grooving, nuclear clearing, and intra-nuclear inclusions.
Basavaraj Rangalakshmi Ashwini   +3 more
doaj   +1 more source

Nuclear functions of mammalian MicroRNAs in gene regulation, immunity and cancer

open access: yesMolecular Cancer, 2018
MicroRNAs (miRNAs) are endogenous non-coding RNAs that contain approximately 22 nucleotides. They serve as key regulators in various biological processes and their dysregulation is implicated in many diseases including cancer and autoimmune disorders. It
Hongyu Liu   +5 more
semanticscholar   +1 more source

Gene regulation by long non-coding RNAs and its biological functions

open access: yesNature reviews. Molecular cell biology, 2020
Evidence accumulated over the past decade shows that long non-coding RNAs (lncRNAs) are widely expressed and have key roles in gene regulation. Recent studies have begun to unravel how the biogenesis of lncRNAs is distinct from that of mRNAs and is ...
Luisa Statello   +3 more
semanticscholar   +1 more source

The radial arrangement of the human chromosome 7 in the lymphocyte cell nucleus is associated with chromosomal band gene density [PDF]

open access: yes, 2008
This is the author's accepted manuscript. The final published article is available from the link below. Copyright @ Springer-Verlag 2008.In the nuclei of human lymphocytes, chromosome territories are distributed according to the average gene density of ...
A Bolzer   +53 more
core   +1 more source

The Role of Nuclear Bodies in Gene Expression and Disease

open access: yesBiology, 2013
This review summarizes the current understanding of the role of nuclear bodies in regulating gene expression. The compartmentalization of cellular processes, such as ribosome biogenesis, RNA processing, cellular response to stress, transcription ...
Marie Morimoto, Cornelius F. Boerkoel
doaj   +1 more source

Genetic and physiological variation in two strains of Japanese quail

open access: yesJournal of Genetic Engineering and Biotechnology, 2021
Background Detecting the genetic and physiological variations in two Japanese quail strains could be used to suggest a new avian model for future breeding studies.
Nashat Saeid Ibrahim   +4 more
doaj   +1 more source

Sigma factor-mediated plastid retrograde signals control nuclear gene expression.

open access: yesThe Plant Journal, 2013
Retrograde signalling from plastids to the nucleus is necessary to regulate the organelle's proteome during the establishment of photoautotrophy and fluctuating environmental conditions.
J. Woodson   +4 more
semanticscholar   +1 more source

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