Results 291 to 300 of about 2,137,659 (362)

Biomimetic Membrane Interface Technologies for Detection and Isolation of CTCs and EVs: Advances and Opportunities in Liquid Biopsy

Advanced Science, EarlyView.
Biomimetic membrane interface engineering constructs functionalized detection platforms by integrating natural cell membranes, synthetic lipids, or hybrid membranes. This strategy effectively reduces background interference and enables efficient target capture and analysis, showing broad applications in circulating tumor cell separation, extracellular ...
Duo Liu, Jie Yu, Jingxue Li, Yixue Chen, Mengle Peng, Yifan Xu, Yongjun Wu, Lihua Ding, Sitian He   +8 more
wiley   +1 more source

KPNA3 regulates histone locus body formation by modulating condensation and nuclear import of NPAT. [PDF]

J Cell Biol
Xu SB, Gao XK, Liang HD, Cong XX, Chen XQ, Zou WK, Tao JL, Pan ZY, Zhao J, Huang M, Bao Z, Zhou YT, Zheng LL.   +12 more
europepmc   +1 more source

Nuclear Import of Microinjected Influenza Virus Ribonucleoproteins

, 1994
Iris Kemler, Gary R. Whittaker, Ari Helenius   +2 more
openalex   +1 more source

Ultrafine Ru‐M Alloy@S Vacancy‐Rich MoS2 Nanosheets With Bimetallic Active Sites for Efficient Hydrogen Evolution in Alkaline and Acidic Media

Advanced Science, EarlyView.
A USMR synthesizes ultrafine RuCo alloy on S‐vacancy‐rich 1T phase MoS2. This method enables rapid precursor mixing, instantaneous reduction, and uniform alloy dispersion while creating S vacancies. The synergy between Ru‐Co sites and defective MoS2 optimizes hydrogen kinetics, achieving a low overpotential of 31 mV@10 mA·cm‐2 in acid, providing a ...
Rui Su, Tiantian Ding, Hao Tang, Xueying Yang, Jie Zhang, Xiaolin Liu, Jinfu Jia, Yuan Liu, Jin Ge, Zhilin Wu, Zhengya Dong, Xiaojing Zhu   +11 more
wiley   +1 more source

ZBTB21 Is a Dual Suppressor of Pyroptosis and MHC‐I Antigen Presentation That Promotes Tumor Immune Evasion

Advanced Science, EarlyView.
ZBTB21 is a transcription factor that epigenetically suppresses pyroptosis and MHC‐I antigen presentation, enabling tumor immune evasion. Genetic ablation of ZBTB21 activates pyroptotic cell death and enhances antigen presentation, recruiting CD8+ T cells to overcome immune checkpoint blockade resistance.
Lei Zhao, Linlin Sheng, Jianhao Qiu, Junjie Ma, Kai Jin, Binggong Zhao, Tianrun Miao, Jing Chen, Yehong Li, Zhan Zhang, Dongfeng Sun, Yongmeng Li, Hui Tian   +12 more
wiley   +1 more source

Structure-function insights into the dual role of African swine fever virus pB318L: A typical geranylgeranyl-diphosphate synthase and a nuclear import protein. [PDF]

Virol Sin
Zhao HF, Wang Y, Liu XH, Liu XH, Geng Z, Gao ZQ, Huang L, Weng CJ, Dong YH, Zhang H.   +9 more
europepmc   +1 more source

Enhanced Responsivity, Accuracy, and Stability of Aerosol Jet Printing via Mechanical Switching Valve Assisted Internal Shuttering

Advanced Science, EarlyView.
This work demonstrates ultra‐high ON‐OFF responsivity of AJP by mechanical switching valve assisted shuttering. The jet relaxation and ON‐OFF delay are substantially eliminated from greater than 35 s, maintaining patterning quality independent of the variations of printing parameters, permitting excellent process stability and universality.
Jinhang Wang, Li Meng, Shuhuan Zhang, Pan Chen, Kaiwen Wei, Beibei Zhu, Xiaoyan Zeng   +6 more
wiley   +1 more source

A bipartite NLS motif mediates the nuclear import of Drosophila moesin. [PDF]

Front Cell Dev Biol
Kovács Z, Bajusz C, Szabó A, Borkúti P, Vedelek B, Benke R, Lipinszki Z, Kristó I, Vilmos P.   +8 more
europepmc   +1 more source

Endothelial PDGF Signaling Dysregulation Impairs Testicular Interstitial Homeostasis in Diabetes

Advanced Science, EarlyView.
Testicular endothelial cells (TECs) function as central signaling hubs that coordinate interstitial homeostasis. Diabetes disrupts TEC‐derived PDGF signaling, silences the JUND‐MCL1 survival program in Leydig cells, and impairs peritubular function, leading to fibrosis and testosterone insufficiency.
Wenxiu Zhang, Kai Hong, Yanling Tang, Lina Cui, Xiaojian Lu, Jianxing Cheng, Yangyi Fang, Qiaoling Jiang, Ziyan Zhuang, Songzhan Gao, Hui Jiang, Qiang Liu, Jingtao Guo, Zhe Zhang, Xiaoyan Wang   +14 more
wiley   +1 more source

Schwann Cell Synthesized Cholesterol Orchestrates Peripheral Nerve Regeneration via Structural and IGF1‐Dependent Signaling Mechanisms

Advanced Science, EarlyView.
This study reveals that Schwann cell FDFT1‐mediated cholesterol synthesis is essential for peripheral nerve regeneration via dual roles: as a structural component for myelin and as a metabolic signal that upregulates IGF1. IGF1 promotes axonal growth through paracrine action and enhances Schwann cell differentiation/ myelination via an intrinsic IGF1R ...
Shuyi Xu, Ye He, Ying Zou, Mengyao Zhao, Jiaqi Zhang, Yizhou Xu, Jiale Cai, Xiongbo Luo, Xinrui Ma, Saini Wu, Yuling Huang, Xianghai Wang, Jiasong Guo   +12 more
wiley   +1 more source