EFTUD2 Regulates Cortical Morphogenesis via Modulation of Caspase‐3 and Aifm1 Splicing Pathways
Advanced Science, EarlyView.EFTUD2, a spliceosomal GTPase linked to MFDM, regulates cortical development through apoptotic control. Conditional Eftud2 knockout in murine neural stem cells induces microcephaly and cortical disorganization, while pathogenic variants drive neuronal loss.
Liping Chen +12 more
wiley +1 more source
Current Progress and Challenges of Electromagnetic Wave Absorbing Materials at High Temperature
Advanced Science, EarlyView.This review explains three dielectric loss mechanisms of electromagnetic wave absorbing materials under high temperatures and the high temperature testing technology is explained. The research progress of carbon‐based, ceramic‐based and metamaterial‐based electromagnetic wave absorbers is analyzed.
Zhixiao Wang +5 more
wiley +1 more source
Advanced Science, EarlyView.Engineered macrophage‐derived exosomes overexpressing GNA12 and GNA13 reprogram glial cells to promote neuroprotection and neural regeneration following SCI. A chitosan‐based thermosensitive hydrogel enables sustained intranasal exosome delivery, bypassing systemic barriers and enhancing therapeutic efficacy.
Yangyang Wang +13 more
wiley +1 more source
Genome - nuclear lamina interactions are multivalent and cooperative
Dauban L +11 more
europepmc +1 more source
The Immune Microenvironment: New Therapeutic Implications in Organ Fibrosis
Advanced Science, EarlyView.This review summarizes recent advances in understanding the immune microenvironment's role in fibrosis, focusing on phenotypic/functional alterations of immune cells and their dynamic interactions with other cellular constituents within tissues. The authors further explore therapeutic opportunities and challenges in targeting immune microenvironment ...
Xiangqi Chen +6 more
wiley +1 more source
The Cooperation of Condensin, Histone Methylation, and Nuclear Lamina Tethering Maintains X Chromosome Repression after the Establishment of Dosage Compensation [PDF]
Jessica Trombley
openalex +1 more source
Color‐Tunable Glass for Adaptable Thermal Management Based on Silver Phase Change
Advanced Science, EarlyView.This article presents an Ag particle‐based thermal management device achieving both selective visible reflection and effective heat flux control. Morphological changes of silver during annealing enable tunable color and thermal regulation via a simple fabrication process.
Mi Jin Hong +7 more
wiley +1 more source
Capturing the Electrical Activity of all Cortical Neurons: Are Solutions Within Reach?
Advanced Science, EarlyView.Despite advancements in implantable electrode technology, challenges persist in scaling up these devices to record most of the neuronal activity across the cortex. This review explores the limitations of both rigid and flexible probes, including tissue damage and foreign body response, while also discussing emerging biohybrid strategies.
Attila Kaszás +5 more
wiley +1 more source
Anti‐Icing Organogel Enables Quasi‐Homogeneous Supercooling Preservation of Mouse Hearts
Advanced Science, EarlyView.An organogel interface with a large energy barrier for ice nucleation is proposed to enable a quasi‐homogeneous supercooling preservation for organs. This method does not rely on cryoprotectant agents or machine perfusion and can double the ex vivo storage time of mouse hearts.
Junhao Li +8 more
wiley +1 more source
Top‐Down Fabricated Wood‐Derived Pressure and Strain Sensors: A Review
Advanced Science, EarlyView.This review focuses on wood‐derived pressure/strain sensors fabricated via top‐down strategies. It analyzes wood's structural composition, examines processing techniques, discusses sensor types and sensing mechanisms, and reviews existing research. The article concludes with future directions for enhancing performance and scalability.
Yi Ren +8 more
wiley +1 more source